PRODUCTION OF D-SORBITOL AND L-ASCORBIC ACID FROM D-GLUCOSE: THEIR PROPERTIES, FIELDS OF USAGE AND EFFECTS ON HEALTH

Abstract

D-sorbitol is a sugar alcohol naturally found in many fruits. L-ascorbic acid is a compound that can be synthesized by plants and some animals but must be externally taken by humans because it cannot be synthesized due to the lack of L-gulono-γ-lactone oxidase enzyme. D-sorbitol and L-ascorbic acid are two ingredients that are frequently used in the food, chemical, pharmaceutical and cosmetic industries and may have a number of positive effects on human health. These ingredients are generally produced commercially from D-glucose by a series of chemical and biochemical reactions. In the commercial production of these compounds, Reichstein-Grüssner or two-step fermentation methods are generally used. In this study; the properties, fields of usage, effects on human health and production methods of D-sorbitol and L-ascorbic acid are reviewed.

Keywords

• D-glucose,hydrogenation,fermentation,Gluconobacter oxydans,Ketogulonicigenum vulgare

D-GLİKOZDAN D-SORBİTOL VE L-ASKORBİK ASİT ÜRETİMİ: BU BİLEŞİKLERİN ÖZELLİKLERİ, KULLANIM ALANLARI VE SAĞLIK ÜZERİNE ETKİLERİ

Abstract

D-sorbitol birçok meyvede doğal olarak bulunan bir şeker alkolüdür. L-askorbik asit ise bitkiler ve bazı hayvanlar tarafından sentezlenebilen ancak insanlar tarafından L-gulono-γ-lakton oksidaz enzimi eksikliği nedeniyle sentezlenemediği için dışarıdan alınması zorunlu olan bir bileşiktir. D-sorbitol ve L-askorbik asit gıda, kimya, ilaç ve kozmetik sektörlerinde sıklıkla kullanılan ve insan sağlığı üzerine birçok olumlu etkileri bulunan iki üründür. Bu ürünler D-glikozdan kimyasal ve biyokimyasal reaksiyonlar ile ticari olarak üretilmektedirler. Bu bileşiklerin ticari üretiminde genellikle Reichstein-Grüssner veya iki aşamalı fermantasyon yöntemleri kullanılmaktadır. Bu çalışmada D-sorbitol ve L-askorbik asidin bazı özellikleri, kullanım alanları, sağlık üzerine etkileri ve üretim yöntemleri derlenmiştir.  

Keywords

• D-glikoz,hidrojenizasyon,fermantasyon,Gluconobacter oxydans,Ketogulonicigenum vulgare

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