Novel Methyl 4,6-O-Benzylidene--D-Glucopyranoside Derivatives: Synthesis, Structural Characterization and Evaluation of Antibacterial Activities

Mirajul Islam; Arifuzzaman Arifuzzaman; Monjur Rahman; Mohammad Atiar Rahman; Sarkar Mohammad Abe Kawsar Kawsar

doi:10.15671/hjbc.622038

Research Article

Year 2019, , 153 - 164, 18.09.2019

Mirajul Islam Arifuzzaman Arifuzzaman Monjur Rahman Mohammad Atiar Rahman Sarkar Mohammad Abe Kawsar Kawsar

https://doi.org/10.15671/hjbc.622038

Cited By: 25

Abstract

References

1.O.Gornik, J. Dumić, M. Flögel, G. Lauc, Glycoscience a new frontier in rational drug design, Acta Pharm., 56 (2006) 19- 30.
2. J. Finkelstein, Editor, Glycochemistry and glycobiology. Nature, 446 (2007) 999-1051.
3. G. Thanh Le, G. Abbenante, B. Becker, M. Grathwohl, J. Halliday, G. Tometzki, J. Zuegg, W. Meutermans, Molecular diversity through sugar scaffolds, Drug Discov. Today, 8 (2003) 701-709.
4. C.M. Nogueira, B.R. Parmanhan, P.P. Farias, A.G. Corrêa. The growing importance of carbohydrates in medicinal chemistry, Rev. Virtual Quim., 1 (2009) 149-159.
5. D.T. Nguyen, T.D. Hoang, T.D. Vu, M.T. Phan, V.Q. Nguyen, Synthesis and antibacterial and antifungal activities of N-(tetra-O-acetyl-β-d-glucopyranosyl) thiosemicarbazones of substituted 4-formylsydnones, Chem. Central J., 9 (2015) 60-74.
6. W. Chi-Huey, (Ed.) Carbohydrate-based drug discovery, Wiley-VCH Verlag GmbH & Co. KGaA: Weinheim, 2003.
7. Y. Shen, Y. Sun, Z. Sang, C. Sun, Y. Dai, Y. Deng, Synthesis, characterization, antibacterial and antifungal evaluation of novel monosaccharide esters, Molecules, 17 (2012) 8661- 8673.
8. A. Aboelmagd, A.I.A. Ibrahim, M.S.S. Ezzeldin, M. Abdel-Razik, Synthesis and antifungal activity of some 2benzothiazolylthioacetyl amino acid and peptide derivatives, ARKIVOC (IX) (2011) 337-353.
9. S.M.A. Kawsar, M. Khaleda, A. Refat, M.A. Manchur, Y. Koide, Y. Ozeki, Infrared, 1H-NMR spectral studies of some methyl 6-O-myristoyl-α-D-glucopyranoside derivatives: assessment of antimicrobial effects, Int. Lett. Chem. Phys. Astron., 58 (2015) 122-136.
10. M.A. Sofan, B.S. Samy, H.S. Kandeel, Antimicrobial activity of newly synthesized thiadiazoles, 5-benzyl-2Htetrazole and their nucleosides, Der Pharm. Chemica, 4 (2012) 1064-1073.
11. S.M.A. Kawsar, A.K.M.S. Kabir, M.M. Manik, M.K. Hossain, M.N. Anwar, Antibacterial and mycelial growth inhibition of some acylated derivatives of D-glucopyranoside, Int. J. Biosci., 2 (2012) 66-73.
12. Y. Tsuda, E. Haque, Regioselective introduction of p-coumaroyl group to α-L-arabinopyranosides. Total synthesis of inundoside-G and inundoside-D1, Chem. Pharm. Bull., 31 (1983) 1437-1439.
13. M. Itoh, D. Hagiwara, J. Notani, A simple and mild esterification method for carboxylic acids using sulfonatetype coupling reagents, Synthesis, 7 (1975) 456-458.
14. Y. Kondo, Selective benzoylation of methyl α- and β-Dxylopyranoside, Carbohydr. Res., 107 (1982) 303-311.
15. J.M. Sugihara, Relative reactivities of hydroxyl groups of carbohydrates, Adv. Carbohydr. Chem., 8 (1953) 1-44.
16. A.K.M.S. Kabir, P. Dutta, M.N. Anwar, Synthesis of some new derivatives of D-mannose, Chittagong Univ. J. Sci., 29 (2005) 01-08.
17. M. Ichinari, K. Nakayama, Y. Hayase, Synthesis of 2,4-dioxoimidazolidines from 2-arylimino-1,3-triazines and their antifungal activity, Heterocycles (Tokyo), 27 (1988) 2635-2641.
18. N.G. Gawande, M.S. Shingare, Synthesis of some thiazolylthiosemicarbazides, triazoles, oxazoles, thiadiazoles & their microbial activity, Ind. J. Chem., 26 (1987) 387-389.
19. R. Gupta, S. Paul, A.K. Gupta, P.L. Kachroo, S. Bani, Synthesis and biological activities of some 2-substituted phenyl-3-(3- alkyl/aryl-5,6-dihydro-s-triazolo[3,4-b][1,3,4]thiazolo-6-yl)- indoles, Ind. J. Chem., 36 (1997) 707-710.
20. H. Singh, K.N. Shukla, R. Dwivedi, L.D.S. Yadav, Clycloaddition of 4-amino-3-mercepto-1,2,4-triazole to heterocumulenes and antifungal activity of the resulting 1,2,4-triazolo[3,4- c]-1,2-dithia-4,5-diazines, J. Agric. Food. Chem., 38 (1990) 1483-1486.
21. S.M.A. Kawsar, M.M. Islam, S.A. Chowdhury, T. Hasan, M.K. Hossain, M.A. Manchur, Y. Ozeki, Design and newly synthesis of some 1,2-O-isopropylidene-α-D-glucofuranose derivatives: characterization and antibacterial screening studies, Hacett. J. Biol. Chem., 41 (2013) 195-206.
22. S.M.A. Kawsar, M.O. Faruk, M.S. Rahman, Y. Fujii, Y. Ozeki, Regioselective synthesis, characterization and antimicrobial activities of some new monosaccharide derivatives, Sci. Pharm., 82 (2014) 1-20.
23. A.K.M.S. Kabir, M.M. Matin, S.M.A. Kawsar, Synthesis and antibacterial activities of some uridine derivatives, Chittagong Univ. J. Sci., 22 (1998) 13-18.
24. A.K.M.S. Kabir, S.M.A. Kawsar, M.M.R. Bhuiyan, S. Hossain, Synthesis and characterization of some uridine derivatives, J. Bang. Chem. Soc., 16 (2003) 6-14.
25. S.M.A. Kawsar, J. Ferdous, G. Mostafa, M.A. Manchur, A synthetic approach of D-glucose derivatives: spectral caracterization and antimicrobial studies, Chem. Chem. Technol. J., 8 (2014) 19-27.
26.S.M.A. Kawsar, A.K.M.S. Kabir, M.M.R. Bhuiyan, J. Ferdous, M.S. Rahman, Synthesis, characterization and microbial screening of some new methyl 4,6-O-(4- methoxybenzylidene)-α-D-glucopyranoside derivatives, J. Bang. Acad. Sci., 37 (2013) 145-158.
27. S.M.A. Kawsar, M.M. Rahman, M. Islam, M.A. Manchur, H. Imtiaj, S. Rajia, An in vitro assessment of antibacterial, antifungal and cytotoxic effects of D-glucopyranoside derivatives, Int. J. Biosci., 12 (2018) 408-416.
28. A.K.M.S. Kabir, S.M.A. Kawsar, M.M.R. Bhuiyan, M.S. Rahman, M.E. Chowdhury, Antimicrobial screening of some derivatives of methyl α-D-glucopyranoside, Pak. J. Sci. Ind. Res., 52 (2009) 138-142.
29. A.K.M.S. Kabir, S.M.A. Kawsar, M.M.R. Bhuiyan, B. Banu, Synthesis of some new derivatives of methyl 4,6-O-cyclohexylidene-α-D-glucopyranoside, J. Bang. Chem. Soc., 21 (2008) 72-80.
30. A.K.M.S. Kabir, S.M.A. Kawsar, M.M.R. Bhuiyan, M.R. Islam, M.S. Rahman, Biological evaluation of some mannopyranoside derivatives, Bull. Pure Appl. Sci., 23 (2004) 83-91.
31. N.K. Richtmeyer, Methods in carbohydrate chemistry, Meth. Carbohydr. Chem., Academic Press Inc. (New York), 1 (1962) 107-111.
32. A.W. Bauer, W.M.M. Kirby, J.C. Sherris, M. Turck, Antibiotic susceptibility testing by a standardized single disc method, Am. J. Clin. Pathol., 45 (1966) 439-476.
33. M.A.T. Miah, H.U. Ahmed, N.R. Sharma, A. Ali, S.A. Miah, Antifungal activity of some plant extracts, Bang. J. Bot., 19 (1990) 05-10.
34. A.K.M.S. Kabir, M.M. Matin, M.J. Alam, M.N. Anwar, Synthesis and antimicrobial activities of some glucopyranoside derivatives, Chittagong Univ. J. Sci., 23 (1999) 25-34.
35. S.M.A. Kawsar, I. Mariam, J. Sanjida, M.A. Manchur, I. Hasan, R. Sultana, Evaluation of the antimicrobial activity and cytotoxic effect of some uridine derivatives, Int. J. Biosci., 12 (2018) 211-219.
36. S.M.A. Kawsar, A.A. Hamida, A,U, Sheikh, M.K. Hossain, A.C. Shagir, A.F.M. Sanaullah, M.A. Manchur, I. Hasan, Y. Ogawa, Y. Fujii, Y. Koide, Y. Ozeki, Chemically modified uridine molecules incorporating acyl residues to enhance antibacterial and cytotoxic activities, Int. J. Org. Chem., 5 (2015) 232-245.
37. S.M.A. Kawsar, U. Sharif, M.A. Manchur, Y. Fujii, Y. Ozeki, Acylation of D-glucose derivatives over C5H5N: spectral characterization and in vitro antibacterial activities, Int. J. Biol. Chem., 9 (2015) 269-282.
38. S.M.A. Kawsar, S.S.B.S. Nishat, M.A. Manchur, Y. Ozeki, Benzenesulfonylation of methyl α-D-glucopyranoside: synthesis, characterization and antibacterial screening, Int. Lett. Chem. Phys. Astron., 64 (2016) 95-105.
39. S.M.A. Kawsar, U. Sharif, S.S.B.S. Nishat, M.A. Manchur, Y. Ozeki, Synthesis, characterization and antibacterial susceptibility of some benzenesulfonyl and N-acetylsulfanilyl derivatives of methyl α-D-glucopyranoside, Curr. Res. Chem., 7 (2015) 21-33.
40. S.M.A. Kawsar, M.O. Faruk, G. Mostafa, M.S. Rahman, Synthesis and spectroscopic characterization of some novel acylated carbohydrate derivatives and evaluation of their antimicrobial activities, Chem. Biol. Interface, 4 (2014) 37-47.
41. Y.M. Kim, S. Farrah, R.H. Baney, Structure-antimicrobial activity relationship for silanols, a new class of disinfectants, compared with alcohols and phenols, Int. J. Antimicrob. Agents, 29 (2007) 217-222.
42. W.A. Hunt, The effects of aliphatic alcohols on the biophysical and biochemical correlates of membrane function, Adv. Exper. Med. Biol., 56 (1975) 195-210.
43. V. Judge, B. Narasimhan, M. Ahuja, D. Sriram, P. Yogeeswari, E.D. Clercq, C. Pannecouque, J. Balzarini, Synthesis, antimycobacterial, antiviral, antimicrobial activity and QSAR studies of N2-acyl isonicotinic acid hydrazide derivatives, Med. Chem., 9 (2013) 53-76.
44. S.M.A. Kawsar, T. Hasan, S.A. CHowdhury, M.M. Islam, M.K. Hossain, M.A. Manchur, Synthesis, spectroscopic characterization and in vitro antibacterial screening of some D-glucose derivatives, Int. J. Pure Appl. Chem., 8 (2013) 125- 135.
45. S.M.A. Kawsar, A.K.M.S. Kabir, M.M.R. Bhuiyan, A. Siddiqa, M.N. Anwar, Synthesis, spectral and antimicrobial screening studies of some acylated D-glucose derivatives, Rajiv Gandhi Univ. Health Sci. (RGUHS) J. Pharm. Sci., 2 (2012) 107-115

Novel Methyl 4,6-O-Benzylidene--D-Glucopyranoside Derivatives: Synthesis, Structural Characterization and Evaluation of Antibacterial Activities

Year 2019, , 153 - 164, 18.09.2019

Mirajul Islam Arifuzzaman Arifuzzaman Monjur Rahman Mohammad Atiar Rahman Sarkar Mohammad Abe Kawsar Kawsar

https://doi.org/10.15671/hjbc.622038

Cited By: 25

Abstract

Carbohydrates are the most abundant and the most diverse biopolymers in nature. Due to the importance of carbohydrates it is necessary to develop a new method for the synthesis of carbohydrate based drugs of the current global situation for health and disease. In this present work we demonstrate the synthesis of methyl 4,6-O-benzylidene--Dglucopyranoside derivatives by direct acylation method. The structures of the newly prepared compounds have been characterized and elucidated using various physico-chemical and spectroscopic methods including elemental analysis, melting point determination, infrared and proton NMR spectroscopy. A number of acyl derivatives were prepared in order to obtain a series of newer components for antibacterial screening experiments. These acylated derivatives were evaluated for in vitro antibacterial screening studies against four human pathogenic bacteria by disc diffusion method.

Keywords

Synthesis, benzylidene, acylation, structure, pathogens

References

1.O.Gornik, J. Dumić, M. Flögel, G. Lauc, Glycoscience a new frontier in rational drug design, Acta Pharm., 56 (2006) 19- 30.
2. J. Finkelstein, Editor, Glycochemistry and glycobiology. Nature, 446 (2007) 999-1051.
3. G. Thanh Le, G. Abbenante, B. Becker, M. Grathwohl, J. Halliday, G. Tometzki, J. Zuegg, W. Meutermans, Molecular diversity through sugar scaffolds, Drug Discov. Today, 8 (2003) 701-709.
4. C.M. Nogueira, B.R. Parmanhan, P.P. Farias, A.G. Corrêa. The growing importance of carbohydrates in medicinal chemistry, Rev. Virtual Quim., 1 (2009) 149-159.
5. D.T. Nguyen, T.D. Hoang, T.D. Vu, M.T. Phan, V.Q. Nguyen, Synthesis and antibacterial and antifungal activities of N-(tetra-O-acetyl-β-d-glucopyranosyl) thiosemicarbazones of substituted 4-formylsydnones, Chem. Central J., 9 (2015) 60-74.
6. W. Chi-Huey, (Ed.) Carbohydrate-based drug discovery, Wiley-VCH Verlag GmbH & Co. KGaA: Weinheim, 2003.
7. Y. Shen, Y. Sun, Z. Sang, C. Sun, Y. Dai, Y. Deng, Synthesis, characterization, antibacterial and antifungal evaluation of novel monosaccharide esters, Molecules, 17 (2012) 8661- 8673.
8. A. Aboelmagd, A.I.A. Ibrahim, M.S.S. Ezzeldin, M. Abdel-Razik, Synthesis and antifungal activity of some 2benzothiazolylthioacetyl amino acid and peptide derivatives, ARKIVOC (IX) (2011) 337-353.
9. S.M.A. Kawsar, M. Khaleda, A. Refat, M.A. Manchur, Y. Koide, Y. Ozeki, Infrared, 1H-NMR spectral studies of some methyl 6-O-myristoyl-α-D-glucopyranoside derivatives: assessment of antimicrobial effects, Int. Lett. Chem. Phys. Astron., 58 (2015) 122-136.
10. M.A. Sofan, B.S. Samy, H.S. Kandeel, Antimicrobial activity of newly synthesized thiadiazoles, 5-benzyl-2Htetrazole and their nucleosides, Der Pharm. Chemica, 4 (2012) 1064-1073.
11. S.M.A. Kawsar, A.K.M.S. Kabir, M.M. Manik, M.K. Hossain, M.N. Anwar, Antibacterial and mycelial growth inhibition of some acylated derivatives of D-glucopyranoside, Int. J. Biosci., 2 (2012) 66-73.
12. Y. Tsuda, E. Haque, Regioselective introduction of p-coumaroyl group to α-L-arabinopyranosides. Total synthesis of inundoside-G and inundoside-D1, Chem. Pharm. Bull., 31 (1983) 1437-1439.
13. M. Itoh, D. Hagiwara, J. Notani, A simple and mild esterification method for carboxylic acids using sulfonatetype coupling reagents, Synthesis, 7 (1975) 456-458.
14. Y. Kondo, Selective benzoylation of methyl α- and β-Dxylopyranoside, Carbohydr. Res., 107 (1982) 303-311.
15. J.M. Sugihara, Relative reactivities of hydroxyl groups of carbohydrates, Adv. Carbohydr. Chem., 8 (1953) 1-44.
16. A.K.M.S. Kabir, P. Dutta, M.N. Anwar, Synthesis of some new derivatives of D-mannose, Chittagong Univ. J. Sci., 29 (2005) 01-08.
17. M. Ichinari, K. Nakayama, Y. Hayase, Synthesis of 2,4-dioxoimidazolidines from 2-arylimino-1,3-triazines and their antifungal activity, Heterocycles (Tokyo), 27 (1988) 2635-2641.
18. N.G. Gawande, M.S. Shingare, Synthesis of some thiazolylthiosemicarbazides, triazoles, oxazoles, thiadiazoles & their microbial activity, Ind. J. Chem., 26 (1987) 387-389.
19. R. Gupta, S. Paul, A.K. Gupta, P.L. Kachroo, S. Bani, Synthesis and biological activities of some 2-substituted phenyl-3-(3- alkyl/aryl-5,6-dihydro-s-triazolo[3,4-b][1,3,4]thiazolo-6-yl)- indoles, Ind. J. Chem., 36 (1997) 707-710.
20. H. Singh, K.N. Shukla, R. Dwivedi, L.D.S. Yadav, Clycloaddition of 4-amino-3-mercepto-1,2,4-triazole to heterocumulenes and antifungal activity of the resulting 1,2,4-triazolo[3,4- c]-1,2-dithia-4,5-diazines, J. Agric. Food. Chem., 38 (1990) 1483-1486.
21. S.M.A. Kawsar, M.M. Islam, S.A. Chowdhury, T. Hasan, M.K. Hossain, M.A. Manchur, Y. Ozeki, Design and newly synthesis of some 1,2-O-isopropylidene-α-D-glucofuranose derivatives: characterization and antibacterial screening studies, Hacett. J. Biol. Chem., 41 (2013) 195-206.
22. S.M.A. Kawsar, M.O. Faruk, M.S. Rahman, Y. Fujii, Y. Ozeki, Regioselective synthesis, characterization and antimicrobial activities of some new monosaccharide derivatives, Sci. Pharm., 82 (2014) 1-20.
23. A.K.M.S. Kabir, M.M. Matin, S.M.A. Kawsar, Synthesis and antibacterial activities of some uridine derivatives, Chittagong Univ. J. Sci., 22 (1998) 13-18.
24. A.K.M.S. Kabir, S.M.A. Kawsar, M.M.R. Bhuiyan, S. Hossain, Synthesis and characterization of some uridine derivatives, J. Bang. Chem. Soc., 16 (2003) 6-14.
25. S.M.A. Kawsar, J. Ferdous, G. Mostafa, M.A. Manchur, A synthetic approach of D-glucose derivatives: spectral caracterization and antimicrobial studies, Chem. Chem. Technol. J., 8 (2014) 19-27.
26.S.M.A. Kawsar, A.K.M.S. Kabir, M.M.R. Bhuiyan, J. Ferdous, M.S. Rahman, Synthesis, characterization and microbial screening of some new methyl 4,6-O-(4- methoxybenzylidene)-α-D-glucopyranoside derivatives, J. Bang. Acad. Sci., 37 (2013) 145-158.
27. S.M.A. Kawsar, M.M. Rahman, M. Islam, M.A. Manchur, H. Imtiaj, S. Rajia, An in vitro assessment of antibacterial, antifungal and cytotoxic effects of D-glucopyranoside derivatives, Int. J. Biosci., 12 (2018) 408-416.
28. A.K.M.S. Kabir, S.M.A. Kawsar, M.M.R. Bhuiyan, M.S. Rahman, M.E. Chowdhury, Antimicrobial screening of some derivatives of methyl α-D-glucopyranoside, Pak. J. Sci. Ind. Res., 52 (2009) 138-142.
29. A.K.M.S. Kabir, S.M.A. Kawsar, M.M.R. Bhuiyan, B. Banu, Synthesis of some new derivatives of methyl 4,6-O-cyclohexylidene-α-D-glucopyranoside, J. Bang. Chem. Soc., 21 (2008) 72-80.
30. A.K.M.S. Kabir, S.M.A. Kawsar, M.M.R. Bhuiyan, M.R. Islam, M.S. Rahman, Biological evaluation of some mannopyranoside derivatives, Bull. Pure Appl. Sci., 23 (2004) 83-91.
31. N.K. Richtmeyer, Methods in carbohydrate chemistry, Meth. Carbohydr. Chem., Academic Press Inc. (New York), 1 (1962) 107-111.
32. A.W. Bauer, W.M.M. Kirby, J.C. Sherris, M. Turck, Antibiotic susceptibility testing by a standardized single disc method, Am. J. Clin. Pathol., 45 (1966) 439-476.
33. M.A.T. Miah, H.U. Ahmed, N.R. Sharma, A. Ali, S.A. Miah, Antifungal activity of some plant extracts, Bang. J. Bot., 19 (1990) 05-10.
34. A.K.M.S. Kabir, M.M. Matin, M.J. Alam, M.N. Anwar, Synthesis and antimicrobial activities of some glucopyranoside derivatives, Chittagong Univ. J. Sci., 23 (1999) 25-34.
35. S.M.A. Kawsar, I. Mariam, J. Sanjida, M.A. Manchur, I. Hasan, R. Sultana, Evaluation of the antimicrobial activity and cytotoxic effect of some uridine derivatives, Int. J. Biosci., 12 (2018) 211-219.
36. S.M.A. Kawsar, A.A. Hamida, A,U, Sheikh, M.K. Hossain, A.C. Shagir, A.F.M. Sanaullah, M.A. Manchur, I. Hasan, Y. Ogawa, Y. Fujii, Y. Koide, Y. Ozeki, Chemically modified uridine molecules incorporating acyl residues to enhance antibacterial and cytotoxic activities, Int. J. Org. Chem., 5 (2015) 232-245.
37. S.M.A. Kawsar, U. Sharif, M.A. Manchur, Y. Fujii, Y. Ozeki, Acylation of D-glucose derivatives over C5H5N: spectral characterization and in vitro antibacterial activities, Int. J. Biol. Chem., 9 (2015) 269-282.
38. S.M.A. Kawsar, S.S.B.S. Nishat, M.A. Manchur, Y. Ozeki, Benzenesulfonylation of methyl α-D-glucopyranoside: synthesis, characterization and antibacterial screening, Int. Lett. Chem. Phys. Astron., 64 (2016) 95-105.
39. S.M.A. Kawsar, U. Sharif, S.S.B.S. Nishat, M.A. Manchur, Y. Ozeki, Synthesis, characterization and antibacterial susceptibility of some benzenesulfonyl and N-acetylsulfanilyl derivatives of methyl α-D-glucopyranoside, Curr. Res. Chem., 7 (2015) 21-33.
40. S.M.A. Kawsar, M.O. Faruk, G. Mostafa, M.S. Rahman, Synthesis and spectroscopic characterization of some novel acylated carbohydrate derivatives and evaluation of their antimicrobial activities, Chem. Biol. Interface, 4 (2014) 37-47.
41. Y.M. Kim, S. Farrah, R.H. Baney, Structure-antimicrobial activity relationship for silanols, a new class of disinfectants, compared with alcohols and phenols, Int. J. Antimicrob. Agents, 29 (2007) 217-222.
42. W.A. Hunt, The effects of aliphatic alcohols on the biophysical and biochemical correlates of membrane function, Adv. Exper. Med. Biol., 56 (1975) 195-210.
43. V. Judge, B. Narasimhan, M. Ahuja, D. Sriram, P. Yogeeswari, E.D. Clercq, C. Pannecouque, J. Balzarini, Synthesis, antimycobacterial, antiviral, antimicrobial activity and QSAR studies of N2-acyl isonicotinic acid hydrazide derivatives, Med. Chem., 9 (2013) 53-76.
44. S.M.A. Kawsar, T. Hasan, S.A. CHowdhury, M.M. Islam, M.K. Hossain, M.A. Manchur, Synthesis, spectroscopic characterization and in vitro antibacterial screening of some D-glucose derivatives, Int. J. Pure Appl. Chem., 8 (2013) 125- 135.
45. S.M.A. Kawsar, A.K.M.S. Kabir, M.M.R. Bhuiyan, A. Siddiqa, M.N. Anwar, Synthesis, spectral and antimicrobial screening studies of some acylated D-glucose derivatives, Rajiv Gandhi Univ. Health Sci. (RGUHS) J. Pharm. Sci., 2 (2012) 107-115

There are 45 citations in total.

Details

Primary Language	English
Subjects	Engineering
Journal Section	Articles
Authors	Mirajul Islam This is me Arifuzzaman Arifuzzaman This is me Monjur Rahman This is me Mohammad Atiar Rahman This is me Sarkar Mohammad Abe Kawsar Kawsar This is me
Publication Date	September 18, 2019
Acceptance Date	February 1, 2017
Published in Issue	Year 2019

Cite

APA	Islam, M., Arifuzzaman, A., Rahman, M., Rahman, M. A., et al. (2019). Novel Methyl 4,6-O-Benzylidene--D-Glucopyranoside Derivatives: Synthesis, Structural Characterization and Evaluation of Antibacterial Activities. Hacettepe Journal of Biology and Chemistry, 47(2), 153-164. https://doi.org/10.15671/hjbc.622038
AMA	Islam M, Arifuzzaman A, Rahman M, Rahman MA, Kawsar SMAK. Novel Methyl 4,6-O-Benzylidene--D-Glucopyranoside Derivatives: Synthesis, Structural Characterization and Evaluation of Antibacterial Activities. HJBC. September 2019;47(2):153-164. doi:10.15671/hjbc.622038
Chicago	Islam, Mirajul, Arifuzzaman Arifuzzaman, Monjur Rahman, Mohammad Atiar Rahman, and Sarkar Mohammad Abe Kawsar Kawsar. “Novel Methyl 4,6-O-Benzylidene--D-Glucopyranoside Derivatives: Synthesis, Structural Characterization and Evaluation of Antibacterial Activities”. Hacettepe Journal of Biology and Chemistry 47, no. 2 (September 2019): 153-64. https://doi.org/10.15671/hjbc.622038.
EndNote	Islam M, Arifuzzaman A, Rahman M, Rahman MA, Kawsar SMAK (September 1, 2019) Novel Methyl 4,6-O-Benzylidene--D-Glucopyranoside Derivatives: Synthesis, Structural Characterization and Evaluation of Antibacterial Activities. Hacettepe Journal of Biology and Chemistry 47 2 153–164.
IEEE	M. Islam, A. Arifuzzaman, M. Rahman, M. A. Rahman, and S. M. A. K. Kawsar, “Novel Methyl 4,6-O-Benzylidene--D-Glucopyranoside Derivatives: Synthesis, Structural Characterization and Evaluation of Antibacterial Activities”, HJBC, vol. 47, no. 2, pp. 153–164, 2019, doi: 10.15671/hjbc.622038.
ISNAD	Islam, Mirajul et al. “Novel Methyl 4,6-O-Benzylidene--D-Glucopyranoside Derivatives: Synthesis, Structural Characterization and Evaluation of Antibacterial Activities”. Hacettepe Journal of Biology and Chemistry 47/2 (September 2019), 153-164. https://doi.org/10.15671/hjbc.622038.
JAMA	Islam M, Arifuzzaman A, Rahman M, Rahman MA, Kawsar SMAK. Novel Methyl 4,6-O-Benzylidene--D-Glucopyranoside Derivatives: Synthesis, Structural Characterization and Evaluation of Antibacterial Activities. HJBC. 2019;47:153–164.
MLA	Islam, Mirajul et al. “Novel Methyl 4,6-O-Benzylidene--D-Glucopyranoside Derivatives: Synthesis, Structural Characterization and Evaluation of Antibacterial Activities”. Hacettepe Journal of Biology and Chemistry, vol. 47, no. 2, 2019, pp. 153-64, doi:10.15671/hjbc.622038.
Vancouver	Islam M, Arifuzzaman A, Rahman M, Rahman MA, Kawsar SMAK. Novel Methyl 4,6-O-Benzylidene--D-Glucopyranoside Derivatives: Synthesis, Structural Characterization and Evaluation of Antibacterial Activities. HJBC. 2019;47(2):153-64.