Adsorption of Bovine Serum Albumin BSA on Clinoptilolite

Year 2008, Volume: 36 Issue: 1, 21 - 29, 01.01.2008

Murat Akgül Neşe Burcu Savak Meryem Özmak Ahu Gümrah Dumanlı Yuda Yürüm Abdülkerim Karabakan

Abstract

The purpose of the present work was to investigate the adsorption of BSA on clinoptilolite in aqueous media. In thisstudy, batch adsorption experiments were carried out and the effects of pH, protein concentration, ionic strength andmodification of zeolite on the adsorption process were examined. The optimum pH for adsorption was found to be4.0. It was found that various treatments applied to modify clinoptilolite has a substantial effect on the adsorption. Inadsorption studies, residual BSA concentration reached equilibrium in a short duration of 60 min. Maximumadsorption capacity value for clinoptilolite in the original form is 388.3 mg BSA/g zeolite 23.2 mg BSA/m2 and in themodified form ranges from 500-660 mg BSA/g zeolite 25-33 mg BSA/m2 showed that this adsorbent, clinoptilolite,was suitable for the adsorption of BSA from aqueous media

Keywords

Clinoptilolite, bovine serum albumin, Adsorption

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