Microwave-Assisted Synthesis and Characterization of Poly 1-Azabicyclo[4.2.0]octane and Its Water-Soluble Derivatives

Year 2008, Volume: 36 Issue: 4, 319 - 328, 01.12.2008

Erdem Karabulut Zafer Ömer Özdemir , Çiğdem Yolaçan Yunus Sarıçay Zeynep Mustafaeva

Abstract

In this study we offer a new method to synthesize positively charged poly 1-Azabicyclo[4.2.0]octane -common nameis polyconidine- and its water-soluble polyampholyte derivative synthesized with bromoacetic acid using microwaveirradiation as a model carrier system for biological macromolecules like peptides, proteins and etc 1-Azabicyclo[4.2.0]octane containing unsubstituted four-membered azetidine ring was synthesized using microwaveassisted synthesis method and used as monomer in cationic ring-opening polymerization. Different alkyl halide derivatives were used as initiators to start polymerization. Microwave-assisted synthesis of polyconidine derivatives was carried out by bromoacetic acid using microwave irradiation. Characterization of polyconidine and its derivatives was achieved by size-exclusion chromatography SEC with on line quadruple detection system, ATR FT-IR and UV Spectroscopy

Keywords

Polyconidine, microwave-assisted polymer synthesis, cationic ring-opening polymerization

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