The Investigation of Fluorescence Biothiol Sensor Properties of 2-(N-hexyl-carbazole-3'-yl)-4- formylpyridine

Year 2021, Volume: 11 Issue: 3, 2184 - 2194, 01.09.2021

Nuray Altınölçek , Ahmet Battal

https://doi.org/10.21597/jist.941474

Cited By: 1

Abstract

The biothiol sensor properties of 2-(N-hexyl-carbazole-3'-yl)-4-formylpyridine molecule were examined. This probe has carbazole moiety as a fluorophore and aldehyde group as a recognition site. Three different biothiol molecules as an analytes were chosen that they are cysteine (Cys), homocysteine (Hcy) and glutathione (GSH). We monitored the adduct formation between probe and analyte (biothiols) by 1H NMR, MS, UV-vis and PL Spectrometers.

Keywords

Aldehyde group, Carbazole, Cysteine, Glutathione, Homocysteine, Biothiol sensor

Project Number

1059B191800354

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