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Diagnostic tests in allergy skin tests, IgE and Specific IgE

Year 2010, Volume: 41 Issue: 2, 87 - 94, 01.03.2010

Levent Midyat

Abstract

The prevalence of allergic diseases has been increasing in recent years, and therefore it is very important to evaluate these patients with appopriate diagnostic tests. Taking a detailed, comprehensive history, and performing a good physical examination of the patient, are the first steps in diagnosing the patient. After the history and physical examination, ordering the appropriate diagnostic tests, and clinical evaluation of the results of these tests are very important. In diagnosing an allergic patient, mainly there are two types of tests; in vitro and in vivo. Serum total IgE, specific IgE, eosinophil count and basophil mediator secretion test are the basic in vitro tests, while skin prick tests and provocation tests are the main in vivo tests.

Keywords

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References

  • 1. Benrıich HH, Ishizaka K, Johansson SG, Rowe DS, Stanworth DR, Terry WD. Immunoglobulin E. A new class of human immunoglobulin. Immunochemistry 1968;5:327-8
  • 2. Klink M, Cline MG, Halonen M, Burrows B. Problems in defining normal limits for serum IgE. J Allergy Clin Immunol 1990; 85:440-4
  • 3. Raymond ZC, Pruzansky JJ. Immunology oflgE-mediated and other hypersensitivity statetes. In, Gramer LC, Greenberger PA eds, Pattert son s Allergic Diseases, 6th ed, Lippincott Williams &Wilkins, 1997:43-54
  • 4. Wide L, Bennich H, Johannson SGO. Diagnosis by an in vitro test for allergen antibodies. Lancet 1967;2:1105-7
  • 5. Hamilton RG, Adkinson Jr NF. In vitro assays for IgE mediated sensitivities. J Allergy Clin Immunol 2004;114:213-25
  • 6. Hamilton RC. Laboratory (In Vitro) analyses. In Donald YML, Sampson HA, Geha RS, Szefler S J eds. Pediatric Allergy: Principles and Practice. 1st ed. St Louis CV Mosby. 2003: 233-42
  • 7. Duran-Tauleria E, Vignati G, Guedan MJA, Peterson CJ. The utility of specific immunoglobulin E measurement in primary care Allergy 2004; 59 (Suppl 78): 35-41 8. Due J, Peitrequin R, Pecoud A. Value of a new screening test for respiratory allergy. Allergy 1988;43:332-7
  • 9. Ballardini N, Nilsson C, Nilsson M, Lilja G. ImmunoCAP Phadiatop Infant - a new blood test for detecting IgE sensitization in children at 2 years of age. Allergy 2006;61:337-43
  • 10. Poon AW, Goodman CS, Rubin RJ. In vitro and skin testing for allergy: comparable clinical utility and costs. Am J Manag Care 1998;4:969-85
  • 11. F. Orhan, T. Karakaş. Allerjik Hastalıklarda Tanı. Türkiye Klinikleri JPediatr Sci 2007, 3(9): 5-11
  • 12. Stern A, van Hage-Hamsten M, Sondell K, Johansson SG. Is allergy screening of blood donors necessary? A comparison between questionnaire answers and the presence of circulating IgE antibodies. Vox Sang 1995;69:114-9
  • 13. Boccagni P, Favari F, Zanoni G, Pezzini A, Tridente G. Comparison of four in vitro assays for specific IgE detection. Int J Clin Lab Res 1994;24:102-5
  • 14. Bernstein IL, Storms WW. Practice parameters for allergy diagnostic testing. Joint Task Force on Practice Parameters for the Diagnosis and Treatment of Asthma. The American Academy of Allergy, Asthma and Immunology and the American College of Allergy, Asthma and Immunology. Ann Allergy Asthma Immunol 1995;75:543-625
  • 15. Position paper, European Academy of Allergology and Clinical Immunology: Allergen standardization and skin tests. Allergy 1993;48:48-82
  • 16. DolovichJ, Hargreave FE, Chalmers R, Shier KJ, Gauldie J, Bienenstock J. Late cutaneous allergic responses in isolated IgEdependent reactions. J Allergy Clin Immunol 1973;52:38-46
  • 17. Frew AJ, Kay AB. Failure to detect deposition of complement and immunoglobulin in allergen-induced late-phase skin reaction in atopic subjects. Clin Exp Immunol 1991;85:70-4
  • 18. Nelson HS. In vivo testing for immunoglobulin E-Mediated sensitivity. In Donald YML, Sampson HA, Geha RS, Szefler SJ eds. Pediatric Alle rgy: Principles and Practice, lsted. St Louis CV Mosby. 2003: 243-51
  • 19. Friedman MM, Kaliner M. Ultrastructural changes in human skin mast cells during antigen-induced degranulation in vivo. J Allergy Clin Immunol 1988;82:998-1005
  • 20. Shalit M, Schwartz LB, von Allmen C, Atkins PC, Lavker RM, Zweiman B. Release of histamine and tryptase during continuous and interrupted cutaneous challenge with allergen in humans. J Allergy Clin Immunol 1990;86:117-25
  • 21. Tripathi and Bernard HB. Diagnosis of immediate hypersensitivity. In, Gramer LC, Greenberger PA eds, Pattertson s Allergic Diseases, 6th ed, Lippincott Williams & Wilkins, 1997:145-58
  • 22. Boyd EL. Cutaneous testing for allergy diagnosis: Comparison of methods in common use. Otolaryngol Clin North Am 2003;36:869- 77
  • 23. Dolen WK. Skin testing techniques. Immunol Allergy Clin North Am 2001;21:273-9
  • 24.K Onbaşı. Allerjik hastalıklarda deri testleri. Astım Allerji İmmünoloji 2007;5(l):33-8
  • 25. Engler DB, DeJarnatt AC, Sim TC, Lee JL, Grant J A. Comparison ofthe sensitivity andprecision of four skin test devices. J Allergy Clin Immunol 1992;90:985-91
  • 26. Dreborg S. Food allergy in pollen-sensitive patients. Ann Allergy 1988;61:41-6
  • 27. Devenney I, Falth-Magnusson K. Skin prick tests may give generalized allergic reactions in infants. Ann Allergy Asthma Immunol 2000;85:457-60
  • 28. Lin MS, Tanner E, Lynn J, Friday GA Jr. Nonfatal systemic allergic reactions induced by skin testing and immunotherapy. Ann Allergy 1993;71:557-62
  • 29. NewhallKK, Saltoun C. Skin testing in allergy. Allergy and Asthma Proceedings 2004;25:5-6
  • 30. Mungan D. Allerji deri testleri. Mısırlıgil Z (editör). Allerjik Hastalıklar. 1. Baskı. Ankara: AntıpA.Ş.,2004:88-98
  • 31.AdinoffÂD, RosloniecDM, McCallLL, Nelson HS. Immediate skin test reactivity to Food and DrugAdministrationapproved standardized extracts. J Allergy Clin Immunol 1990; 86:766-74
  • 32. Tripathi A, Booth BH. Diagnosis of immediate hypersensitivity. In: Grammer LC, Greenberger PA, eds. Patterson's Allergic Diseases, 6th ed. Philadelphia, PA: Lippincott Williams ed Wilkins; 2002. p. 145-57
  • 33. BoyvatA. Kontakt dermatit. Mısırlıgil Z (editör). Allerjik Hastalıklar. 1. Baskı. Ankara: Antıp A.Ş., 2004:359-82
  • 34. Demoly P, Piette V, Bosquet J. In vivo methods for study of allergy. In: Adkinson NF, Yunginger JW, Buse WW, Bochner BS, Holgate ST, Simons FER, eds. Middleton's Allergy Principles and Practice. 6th ed. Philadelphia: Mosby; 2003.p.631-43
  • 35. Hagy GW, Settipane GA. Prognosis of positive allergy skin tests in an asymptomatic population. A three year follow-up of college students. J Allergy Clin Immunol 1971;48:200-11
  • 36. Bahna SL. Food challenge procedures in research and in clinical practice. Pediatr Allergy Immunol 1995;6:49-53. 37. Bangash SA, Bahna SL. Pediatric food allergy update. Curr Allergy and Asthma Rep 2005;5:43 7-44
  • 37. Cartier A, Bernstein IL, Burge PS, et al. Guidelines for bronchoprovocation in the investigation of occupational asthma: Report of the subcommittee on bronchoprovocation for occupational asthma. J Allergy Clin Immunol 1989;84:823-9

Alerjide tanısal testler deri testleri, IgE ve Spesifik IgE

Year 2010, Volume: 41 Issue: 2, 87 - 94, 01.03.2010

Levent Midyat

Abstract

Son yıllarda alerjik hastalıkların sıklığının giderek artması nedeniyle, tanısal yaklaşım da büyük önem kazanmaktadır. Alerjik hastalıkların tanısında, tüm hastalıklar da olduğu gibi ilk basamak, hastanın semptomlarının ayrıntılı sorgulandığı iyi bir öykü alınması ve özellikle alerjik hastalıkların klinik belirtilerinin arandığı sistemik bir muayenenin yapılmasıdır. Öykü ve fizik muayene sonrasında uygun laboratuar testlerinin istenmesi ve bunların klinik yorumu son derece önemlidir. Alerjik hastalıkların tanısında kullanılan testler, invitro ve invivo testler olarak iki gruba ayrılabilinir. İnvitro testler, başlıca serum total IgE, spesifik IgE, eozinofil sayımları ve bazofil mediyatör salgılama testi gibi hücresel testler, invivo testler ise, başlıca deri testleri ve provokasyon testlerinden oluşmaktadır

Keywords

-

References

  • 1. Benrıich HH, Ishizaka K, Johansson SG, Rowe DS, Stanworth DR, Terry WD. Immunoglobulin E. A new class of human immunoglobulin. Immunochemistry 1968;5:327-8
  • 2. Klink M, Cline MG, Halonen M, Burrows B. Problems in defining normal limits for serum IgE. J Allergy Clin Immunol 1990; 85:440-4
  • 3. Raymond ZC, Pruzansky JJ. Immunology oflgE-mediated and other hypersensitivity statetes. In, Gramer LC, Greenberger PA eds, Pattert son s Allergic Diseases, 6th ed, Lippincott Williams &Wilkins, 1997:43-54
  • 4. Wide L, Bennich H, Johannson SGO. Diagnosis by an in vitro test for allergen antibodies. Lancet 1967;2:1105-7
  • 5. Hamilton RG, Adkinson Jr NF. In vitro assays for IgE mediated sensitivities. J Allergy Clin Immunol 2004;114:213-25
  • 6. Hamilton RC. Laboratory (In Vitro) analyses. In Donald YML, Sampson HA, Geha RS, Szefler S J eds. Pediatric Allergy: Principles and Practice. 1st ed. St Louis CV Mosby. 2003: 233-42
  • 7. Duran-Tauleria E, Vignati G, Guedan MJA, Peterson CJ. The utility of specific immunoglobulin E measurement in primary care Allergy 2004; 59 (Suppl 78): 35-41 8. Due J, Peitrequin R, Pecoud A. Value of a new screening test for respiratory allergy. Allergy 1988;43:332-7
  • 9. Ballardini N, Nilsson C, Nilsson M, Lilja G. ImmunoCAP Phadiatop Infant - a new blood test for detecting IgE sensitization in children at 2 years of age. Allergy 2006;61:337-43
  • 10. Poon AW, Goodman CS, Rubin RJ. In vitro and skin testing for allergy: comparable clinical utility and costs. Am J Manag Care 1998;4:969-85
  • 11. F. Orhan, T. Karakaş. Allerjik Hastalıklarda Tanı. Türkiye Klinikleri JPediatr Sci 2007, 3(9): 5-11
  • 12. Stern A, van Hage-Hamsten M, Sondell K, Johansson SG. Is allergy screening of blood donors necessary? A comparison between questionnaire answers and the presence of circulating IgE antibodies. Vox Sang 1995;69:114-9
  • 13. Boccagni P, Favari F, Zanoni G, Pezzini A, Tridente G. Comparison of four in vitro assays for specific IgE detection. Int J Clin Lab Res 1994;24:102-5
  • 14. Bernstein IL, Storms WW. Practice parameters for allergy diagnostic testing. Joint Task Force on Practice Parameters for the Diagnosis and Treatment of Asthma. The American Academy of Allergy, Asthma and Immunology and the American College of Allergy, Asthma and Immunology. Ann Allergy Asthma Immunol 1995;75:543-625
  • 15. Position paper, European Academy of Allergology and Clinical Immunology: Allergen standardization and skin tests. Allergy 1993;48:48-82
  • 16. DolovichJ, Hargreave FE, Chalmers R, Shier KJ, Gauldie J, Bienenstock J. Late cutaneous allergic responses in isolated IgEdependent reactions. J Allergy Clin Immunol 1973;52:38-46
  • 17. Frew AJ, Kay AB. Failure to detect deposition of complement and immunoglobulin in allergen-induced late-phase skin reaction in atopic subjects. Clin Exp Immunol 1991;85:70-4
  • 18. Nelson HS. In vivo testing for immunoglobulin E-Mediated sensitivity. In Donald YML, Sampson HA, Geha RS, Szefler SJ eds. Pediatric Alle rgy: Principles and Practice, lsted. St Louis CV Mosby. 2003: 243-51
  • 19. Friedman MM, Kaliner M. Ultrastructural changes in human skin mast cells during antigen-induced degranulation in vivo. J Allergy Clin Immunol 1988;82:998-1005
  • 20. Shalit M, Schwartz LB, von Allmen C, Atkins PC, Lavker RM, Zweiman B. Release of histamine and tryptase during continuous and interrupted cutaneous challenge with allergen in humans. J Allergy Clin Immunol 1990;86:117-25
  • 21. Tripathi and Bernard HB. Diagnosis of immediate hypersensitivity. In, Gramer LC, Greenberger PA eds, Pattertson s Allergic Diseases, 6th ed, Lippincott Williams & Wilkins, 1997:145-58
  • 22. Boyd EL. Cutaneous testing for allergy diagnosis: Comparison of methods in common use. Otolaryngol Clin North Am 2003;36:869- 77
  • 23. Dolen WK. Skin testing techniques. Immunol Allergy Clin North Am 2001;21:273-9
  • 24.K Onbaşı. Allerjik hastalıklarda deri testleri. Astım Allerji İmmünoloji 2007;5(l):33-8
  • 25. Engler DB, DeJarnatt AC, Sim TC, Lee JL, Grant J A. Comparison ofthe sensitivity andprecision of four skin test devices. J Allergy Clin Immunol 1992;90:985-91
  • 26. Dreborg S. Food allergy in pollen-sensitive patients. Ann Allergy 1988;61:41-6
  • 27. Devenney I, Falth-Magnusson K. Skin prick tests may give generalized allergic reactions in infants. Ann Allergy Asthma Immunol 2000;85:457-60
  • 28. Lin MS, Tanner E, Lynn J, Friday GA Jr. Nonfatal systemic allergic reactions induced by skin testing and immunotherapy. Ann Allergy 1993;71:557-62
  • 29. NewhallKK, Saltoun C. Skin testing in allergy. Allergy and Asthma Proceedings 2004;25:5-6
  • 30. Mungan D. Allerji deri testleri. Mısırlıgil Z (editör). Allerjik Hastalıklar. 1. Baskı. Ankara: AntıpA.Ş.,2004:88-98
  • 31.AdinoffÂD, RosloniecDM, McCallLL, Nelson HS. Immediate skin test reactivity to Food and DrugAdministrationapproved standardized extracts. J Allergy Clin Immunol 1990; 86:766-74
  • 32. Tripathi A, Booth BH. Diagnosis of immediate hypersensitivity. In: Grammer LC, Greenberger PA, eds. Patterson's Allergic Diseases, 6th ed. Philadelphia, PA: Lippincott Williams ed Wilkins; 2002. p. 145-57
  • 33. BoyvatA. Kontakt dermatit. Mısırlıgil Z (editör). Allerjik Hastalıklar. 1. Baskı. Ankara: Antıp A.Ş., 2004:359-82
  • 34. Demoly P, Piette V, Bosquet J. In vivo methods for study of allergy. In: Adkinson NF, Yunginger JW, Buse WW, Bochner BS, Holgate ST, Simons FER, eds. Middleton's Allergy Principles and Practice. 6th ed. Philadelphia: Mosby; 2003.p.631-43
  • 35. Hagy GW, Settipane GA. Prognosis of positive allergy skin tests in an asymptomatic population. A three year follow-up of college students. J Allergy Clin Immunol 1971;48:200-11
  • 36. Bahna SL. Food challenge procedures in research and in clinical practice. Pediatr Allergy Immunol 1995;6:49-53. 37. Bangash SA, Bahna SL. Pediatric food allergy update. Curr Allergy and Asthma Rep 2005;5:43 7-44
  • 37. Cartier A, Bernstein IL, Burge PS, et al. Guidelines for bronchoprovocation in the investigation of occupational asthma: Report of the subcommittee on bronchoprovocation for occupational asthma. J Allergy Clin Immunol 1989;84:823-9
There are 36 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Levent Midyat This is me

Publication Date March 1, 2010
Published in Issue Year 2010 Volume: 41 Issue: 2

Cite

APA Midyat, L. (2010). Alerjide tanısal testler deri testleri, IgE ve Spesifik IgE. Zeynep Kamil Tıp Bülteni, 41(2), 87-94. https://doi.org/10.16948/zktb.86635
AMA Midyat L. Alerjide tanısal testler deri testleri, IgE ve Spesifik IgE. Zeynep Kamil Tıp Bülteni. March 2010;41(2):87-94. doi:10.16948/zktb.86635
Chicago Midyat, Levent. “Alerjide tanısal Testler Deri Testleri, IgE Ve Spesifik IgE”. Zeynep Kamil Tıp Bülteni 41, no. 2 (March 2010): 87-94. https://doi.org/10.16948/zktb.86635.
EndNote Midyat L (March 1, 2010) Alerjide tanısal testler deri testleri, IgE ve Spesifik IgE. Zeynep Kamil Tıp Bülteni 41 2 87–94.
IEEE L. Midyat, “Alerjide tanısal testler deri testleri, IgE ve Spesifik IgE”, Zeynep Kamil Tıp Bülteni, vol. 41, no. 2, pp. 87–94, 2010, doi: 10.16948/zktb.86635.
ISNAD Midyat, Levent. “Alerjide tanısal Testler Deri Testleri, IgE Ve Spesifik IgE”. Zeynep Kamil Tıp Bülteni 41/2 (March 2010), 87-94. https://doi.org/10.16948/zktb.86635.
JAMA Midyat L. Alerjide tanısal testler deri testleri, IgE ve Spesifik IgE. Zeynep Kamil Tıp Bülteni. 2010;41:87–94.
MLA Midyat, Levent. “Alerjide tanısal Testler Deri Testleri, IgE Ve Spesifik IgE”. Zeynep Kamil Tıp Bülteni, vol. 41, no. 2, 2010, pp. 87-94, doi:10.16948/zktb.86635.
Vancouver Midyat L. Alerjide tanısal testler deri testleri, IgE ve Spesifik IgE. Zeynep Kamil Tıp Bülteni. 2010;41(2):87-94.