PANAX GİNSENG KULLANAN BİR HASTADA GELİŞEN ANAFLAKTİK ŞOK OLGUSU

Yıl 2018, VAKA SUNUMU ÖZEL SAYI, 40 - 44, 30.07.2018

Ahmet Aydın

https://doi.org/10.30569/adiyamansaglik.428396

Öz

Bitkisel
ilaçların kullanılmasındaki artış beraberinde hayatı tehdit eden birçok komplikasyonların
ortaya çıkmasına neden olmuştur. Panax yıllardır bir çok hastalığa karşı iyi
geldiği, fiziksel performansı arttırdığı düşüncesiyle bir adaptojen olarak
kullanılmaktadır. Yabancı kaynaklarda ginsenglere karşı gelişen allerji
vakaları bildirilmiştir. Bu yazıda Panax kullanan bir hastada gelişen allerji
olgusu sunuldu. 60 yaşında solunum sıkıntısı, hipotansiyon, şuur kaybı ve yüzde
şişlik şikâyetleri ile acil servise getirilen hasta anaflaktik şok
tablosundaydı. Hastanın Panax adlı bitkisel ilacı kullandığı öğrenildi. Hastaya
müdahale edildikten sonra yoğun bakım ünitesine alınarak takip tedavisine
başlandı. Hasta kliniği düzeldikten sonra servise çıkışı yapıldı. Tedavi
sonrası hasta bilgilendirilerek taburcu edildi.

Anahtar Kelimeler

Panax, Anaflaktik Şok, allerji

DEVELOPMENT OF ANAPHYLACTIC SHOCK IN A PATIENT USING PANAX GINSENG: A CASE REPORT

Öz

 

Recent increase
in the use of herbal preparatıons has led to emergence of various
life-threatening complications. Asian ginseng (Panax ginseng) has been used over many years as an adaptogen with
the anticipation of treating various illnesses and improving physical
performance. Previous cases of allergy against ginseng have been reported in
literature. This report presents a case of allergy developing in a patient
using Asian ginseng. A 60-year-old patient with respiratory complaints,
hypotension, loss of consciousness, and swelling of the face was brought to the
emergency room and had anaphylactic shock. It was found out that the patient
had been using an herbal preparation of Asian ginseng. The patient was
stabilized and taken to intensive care unit for treatment. When the clinical
findings improved, the patient was transferred to in-patient clinic for further
monitoring. Later, the patient was informed and discharged.

Anahtar Kelimeler

Panax, anaphylactic shock, Allergy

Kaynakça

• 1. Kiefer D, Pantuso T. Panax ginseng. Am Fam Physician 2003;68:1539-42.
• 2. Simons FER, Ardusso LRF, Bilo MB, El- Gamal YM, Ledford DK, Ring J, et al. World Allergy Organization guidelines for the assessment and management of anaphylaxis. J Allergy Clin Immunol 2011;127:587-93. https://doi.org/10.1016/j.jaci.2011.01.038
• 3. O’Hara MA, Kiefer D, Farrell K, Kemper KA. Review of 12 commonly used medicinal herbs. Arch Fam Med. 1998; 7(6): 523-536.
• 4. Shamloul R. Natural aphrodisiacs. J Sex Med 2010;7:39–49
• 5. Gillis CN. Panax ginseng pharmacology: a nitric oxide link? Biochem Pharmacol 1997;54:1-8
• 6. Snyder SH. Nitric oxide: First in a new class of neurotransmitters. Science 1992;257: 494-6
• 7. Talasaz AH, Abbasi MR, Abkhiz S, Dashti-Khavidaki S. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. Nephrol Dial Transplant 2010;25:3792-3.
• 8. Güneş H, Küçükdurmaz Z, Karapınar H, Gül İ. Acute anterior myocardial infarction presented with cardiogenic shock in a patient on herbal medication. Turk Kardiyol Dern Ars 2012;40:262-4.
• 9. Vatankulu MA, Tasal A, Erdoğan E, Göktekin Ö. Three case reports of the use of herbal combinations resulted in stent thrombosis: herbal combinations; friend or foe? Turk Kardiyol Dern Ars 2012;40:265-8.
• 10. Yüksel İA, Arslan Ş, Çağrıcı G, Yılmaz A, Acute massive pulmonary embolism in a patient using clavis panax, Türk Kardiyol Dern Arş -2013;41(4):351-353.
• 11. Bahrke M, Morgan W. Evaluation of the ergogenic properties of ginseng. Sports Med. 1994;18(4) : 229-248.
• 12. Choo MK, Park EK, Han MJ, Kim DH. Antiallergic activity of ginseng and its ginsenosides. Planta Med. 2003;69:518-522
• 13. Lee JY, Jin HJ, Park JW, Jung SK, Jang JY, Park HS. A Case of Korean Ginseng-Induced Anaphylaxis Confirmed by Open Oral Challenge and Basophil Activation Test. Allergy Asthma Immunol Res. 2012 March;4(2):110-111.
• 14. Kim KM, Kwon HS, Jeon SG, Park CH, Sohn SW, Kim DI, Kim SS, Chang YS, Kim YK, Cho SH, et al. Korean ginseng-induced occupational asthma and determination of IgE binding components. J Korean Med Sci 2008;23:232-5.
• 15. Wiwanitkit V, Taungjaruwinai W. A case report of suspect ginseng allergy. MedGen Med 2004;6:9