Akut ürtikerli çocuklarda besin duyarlılığı ve yaşın duyarlılık üzerine etkisi

Yıl 2023, Cilt: 9 Sayı: 2, 68 - 73, 30.08.2023

Velat Çelik , Fedli Emre Kılıç , Hüseyin Tanrıverdi

https://doi.org/10.30569/adiyamansaglik.1294989

Öz

Amaç: Çalışmamızda Adıyaman ilinde akut ürtiker (AÜ) şikâyeti ile başvuran çocuklarda en sık duyarlılığa sebep olan besinleri belirlemeyi amaçladık.
Gereç ve Yöntem: Adıyaman Eğitim ve Araştırma Hastanesi'nde Eylül 2021-Mayıs 2022 tarihleri arasında AÜ tanısıyla deri prik testi yapılan 70 çocuğun sonuçları analiz edildi.
Bulgular: On (%14,3) çocukta en az bir besine duyarlılık saptandı. Beş (%7,1) çocukta yumurtaya, dört (%5,7) çocukta inek sütüne, üçer çocukta (%4,3) yer fıstığı, ceviz, antep fıstığı ve fındığa, ikişer çocukta (%2,9) buğday ve tavuk etine, bir çocukta (%1,4) ise kırmızı ete duyarlılık tespit edildi. Yirmidört ay ve altı çocukların %38,1'inde besin duyarlılığı bulunurken, 24 ay üzeri çocukların %4,1'inde besin duyarlılığı tespit edildi (p=0,001).
Sonuç: Adıyaman ilinde AÜ’li çocuklardaki duyarlılığa sebep olan en sık besinler yumurta, inek sütü, yer fıstığı ve ağaç kuruyemişleridir. ≤24 ay çocuklarda besin duyarlılık sıklığının daha büyük çocuklara göre daha yüksek olduğunu bulduk.

Anahtar Kelimeler

Akut ürtiker, Anafilaksi, Besin alerjisi, Çocuklar, Deri prik testi

Destekleyen Kurum

Yok

Proje Numarası

Yok

Teşekkür

Yok

Food sensitivity in children with acute urticaria and the effect of age on sensitivity

Öz

Aim: We aimed to determine the most common foods that cause sensitivity in children with acute urticaria (AU) in Adıyaman province.
Materials and Methods: The results of 70 children who underwent skin prick tests for AU between September 2021-May 2022 at Adıyaman Training and Research Hospital were analyzed.
Results: Sensitivity to at least one food was detected in 10 (14,3%) children. Five (7.1%) children were sensitized to egg, four (5.7%) to cow's milk, three (4.3%) each to peanut, walnut, pistachio, and hazelnut, two (2.9%) each to wheat and chicken meat and one (1.4%) child to beef. While 38.1% of children 24 months and younger had food sensitization 4.1% of children over 24 months had food sensitization (p=0.001).
Conclusion: The most common food sensitivities in Adıyaman province are egg, cow's milk, peanut, and tree nuts in children with AU. We found that the frequency of food sensitivities was higher in ≤24 months old children than older children.

Anahtar Kelimeler

Acute urticaria, Anaphylaxis, Children, Food allergy, Skin prick test

Proje Numarası

Yok

Kaynakça

• Zuberbier T, Abdul Latiff AH, Abuzakouk M, et al. The international EAACI/GA(2)LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria. Allergy. 2022;77(3):734-766.
• Stallings A, Dreskin S, Frank M, Sicherer S. Urticaria (Hives) and Angioedema. In: Kliegman M, St Geme J, Blum N, Shah S, Tasker R, Wilson K, eds. Nelson Textbook of Pediatrics. 21 ed. Philadelphia, PA: Elsevier; 2020:1222-1228.
• Antia C, Baquerizo K, Korman A, Bernstein JA, Alikhan A. Urticaria: A comprehensive review: Epidemiology, diagnosis, and work-up. J Am Acad Dermatol. 2018;79(4):599-614.
• Arı H, Guvenir H, Toyran M, et al. Etiological Assessment of Acute Urticaria in Children. Turkish Journal of Pediatric Disease. 2023;17:13-18.
• Sicherer SH, Sampson HA. Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management. J Allergy Clin Immunol. 2018;141(1):41-58.
• Tam JS. Cutaneous Manifestation of Food Allergy. Immunol Allergy Clin North Am. 2017;37(1):217-231.
• Peters RL, Krawiec M, Koplin JJ, Santos AF. Update on food allergy. Pediatr Allergy Immunol. 2021;32(4):647-657.
• Muraro A, Worm M, Alviani C, et al. EAACI guidelines: Anaphylaxis (2021 update). Allergy. 2022;77(2):357-377.
• Akarsu A, Ocak M, Koken G, Sahiner UM, Soyer O, Sekerel BE. IgE mediated food allergy in Turkey: different spectrum, similar outcome. Turk J Pediatr. 2021;63(4):554-563.
• Kahveci M, Koken G, Sahiner UM, Soyer O, Sekerel BE. Immunoglobulin E-Mediated Food Allergies Differ in East Mediterranean Children Aged 0-2 Years. Int Arch Allergy Immunol. 2020;181(5):365-374.
• Heinzerling L, Mari A, Bergmann KC, et al. The skin prick test - European standards. Clin Transl Allergy. 2013;3(1):3.
• Lote S, Gupta SB, Poulose D, et al. Role of the Skin Prick Test in Urticaria Patients. Cureus. 2022;14(2):e21818.
• Barni S, Liccioli G, Sarti L, Giovannini M, Novembre E, Mori F. Immunoglobulin E (IgE)-Mediated Food Allergy in Children: Epidemiology, Pathogenesis, Diagnosis, Prevention, and Management. Medicina (Kaunas). 2020;56(3).
• Guillet MH, Guillet G. [Food urticaria in children. Review of 51 cases]. Allerg Immunol (Paris). 1993;25(8):333-338.
• Mills EN, Mackie AR, Burney P, et al. The prevalence, cost and basis of food allergy across Europe. Allergy. 2007;62(7):717-722.
• Gupta RS, Springston EE, Warrier MR, et al. The prevalence, severity, and distribution of childhood food allergy in the United States. Pediatrics. 2011;128(1):e9-17.
• Venter C, Pereira B, Voigt K, et al. Prevalence and cumulative incidence of food hypersensitivity in the first 3 years of life. Allergy. 2008;63(3):354-359.
• Leung TF, Yung E, Wong YS, Lam CW, Wong GW. Parent-reported adverse food reactions in Hong Kong Chinese pre-schoolers: epidemiology, clinical spectrum and risk factors. Pediatr Allergy Immunol. 2009;20(4):339-346.
• Bingol A, Uygun DFK, Akdemir M, et al. Clinical phenotypes of childhood food allergies based on immune mechanisms: A multicenter study. Allergy Asthma Proc. 2021;42(3):e86-e95.
• Ricci G, Giannetti A, Belotti T, et al. Allergy is not the main trigger of urticaria in children referred to the emergency room. J Eur Acad Dermatol Venereol. 2010;24(11):1347-1348.
• Bezirganoglu H, Arik Yilmaz E, Sahiner UM, et al. The common triggers of urticaria in children admitted to the pediatric emergency room. Pediatr Dermatol. 2022;39(5):695-701.
• Bernstein JA, Lang DM, Khan DA, et al. The diagnosis and management of acute and chronic urticaria: 2014 update. J Allergy Clin Immunol. 2014;133(5):1270-1277.
• Dinulos J. Urticaria, Angioedema, and Pruritus In: Habif's Clinical Dermatology. 7 ed.: Elsevier 2019:176-214.
• Jeong K, Lee JD, Kang DR, Lee S. A population-based epidemiological study of anaphylaxis using national big data in Korea: trends in age-specific prevalence and epinephrine use in 2010-2014. Allergy Asthma Clin Immunol. 2018;14:31.
• Nettis E, Foti C, Ambrifi M, et al. Urticaria: recommendations from the Italian Society of Allergology, Asthma and Clinical Immunology and the Italian Society of Allergological, Occupational and Environmental Dermatology. Clin Mol Allergy. 2020;18:8.
• Aydogan M, Topal E, Uysal P, et al. Proven Food-Induced Acute Urticaria and Predictive Factors for Definitive Diagnosis in Childhood. Int Arch Allergy Immunol. 2021;182(7):607-614.