Quantitative Analysis of Bioactive Compounds by High‑Performance Liquid Chromatography in Origanum bilgeri
Öz
Origanum genus is an aromatic and medicinal plant with significant bioactive compounds. Origanum species have been used as a folk medicine for years. In this study, the aerial part of Origanum bilgeri P.H. Davis was extracted with hexane and methanol successively, the methanol extract was used for quantitative analysis of bioactive compounds by High‑Performance Liquid Chromatography. Rosmarinic acid was found as a major product (26.61 mg/g extract). The other major compounds were detected as catechin hydride (5.65 mg/g extract), trans-cinnamic acid (2.65 mg/g extract), and resveratrol (1.33 mg/g extract). Consequently, Origanum bilgeri may be a valuable material for drug development and food.
Anahtar Kelimeler
Kaynakça
- De, P., Baltas, M., & Bedos-Belval, F. (2011). Cinnamic acid derivatives as anticancer agents-a review. Current Medicinal Chemistry, 18(11), 1672-1703. doi:https://doi.org/10.2174/092986711795471347
- Demirtas, I., Erenler, R., Elmastas, M., & Goktasoglu, A. (2013). Studies on the antioxidant potential of flavones of Allium vineale isolated from its water-soluble fraction. Food Chemistry, 136(1), 34-40. doi:https://doi.org/10.1016/j.foodchem.2012.07.086
- Elmastas, M., Celik, S. M., Genc, N., Aksit, H., Erenler, R., & Gulcin, İ. (2018). Antioxidant activity of an anatolian herbal tea—Origanum minutiflorum: isolation and characterization of its secondary metabolites. International Journal of Food Properties, 21(1), 374-384. doi:https://doi.org/10.1080/10942912.2017.1416399
- Elmastas, M., Ozturk, L., Gokce, I., Erenler, R., & Aboul‐Enein, H. Y. (2004). Determination of antioxidant activity of marshmallow flower (Althaea officinalis L.). Analytical Letters, 37(9), 1859-1869. doi:https://doi.org/10.1081/AL-120039431
- Elmastaş, M., Telci, İ., Akşit, H., & Erenler, R. (2015). Comparison of total phenolic contents and antioxidant capacities in mint genotypes used as spices/Baharat olarak kullanılan nane genotiplerinin toplam fenolik içerikleri ve antioksidan kapasitelerinin karşılaştırılması. Turkish Journal of Biochemistry, 40(6), 456-462. doi:https://doi.org/10.1515/tjb-2015-0034
- Erenler, R., Adak, T., Karan, T., Elmastas, M., Yildiz, I., Aksit, H., . . . Sanda, M. A. (2017). Chemical Constituents isolated from Origanum solymicum with Antioxidant activities. The Eurasia Proceedings of Science, Technology, Engineering & Mathematics, 1, 139-145.
- Erenler, R., Demirtas, I., Karan, T., Gul, F., Kayir, O., & Karakoc, O. C. (2018). Chemical constituents, quantitative analysis and insecticidal activities of plant extract and essential oil from Origanum onites L. Trends in Phytochemical Research, 2(2), 91-96.
- Erenler, R., Meral, B., Sen, O., Elmastas, M., Aydin, A., Eminagaoglu, O., & Topcu, G. (2017). Bioassay-guided isolation, identification of compounds from Origanum rotundifolium and investigation of their antiproliferative and antioxidant activities. Pharmaceutical Biology, 55(1), 1646-1653. doi:https://doi.org/10.1080/13880209.2017.1310906
- Erenler, R., Sen, O., Aksit, H., Demirtas, I., Yaglioglu, A. S., Elmastas, M., & Telci, İ. (2016). Isolation and identification of chemical constituents from Origanum majorana and investigation of antiproliferative and antioxidant activities. Journal of the Science of Food and Agriculture, 96(3), 822-836. doi:https://doi.org/10.1002/jsfa.7155
- Erenler, R., Telci, I., Ulutas, M., Demirtas, I., Gul, F., Elmastas, M., & Kayir, O. (2015). Chemical Constituents, Quantitative Analysis and Antioxidant Activities of Echinacea purpurea (L.) Moench and Echinacea pallida (Nutt.) Nutt. Journal of Food Biochemistry, 39(5), 622-630. doi:https://doi.org/10.1111/jfbc.12168
