Karaciğerde Detoksifikasyon

Öz

Karaciğer, hayatın devamı için birçok fizyolojik ve biyokimyasal olayın meydana geldiği yerdir. Karaciğer içerisinde bir seri kompleks tepkime gerçekleşir ve zararlı rnaddeleri zehirsizleştirir. Bu olaya detoksifikasyon denir. Detoksifikasyon faz I ve faz II olarak iki basamakta gerçekleşir. Bu derlemede; karaciğerin detoksifikasyonunda etkili olan enzimler ve bu enzimlerin genlerle ilişkisi, inhibisyonu, indüksiyonu ve detoksifikasyonunun besinlerle etkileşimi araştırılarak sunulmuştur.

Anahtar Kelimeler

• Antioksidant
• CytP450
• detoksifikasyon
• karaciğer

Detoxification in Liver

Öz

The liver is where physological and biochemical events occur for living. A series of complex chemical reaction occurs and detoxifies harmful substances in the liver. This event is called "detoxification". It realizes in two stages as phase I and phase II. It's represented by researching enzymes which effect liver detoxification and relevent with genes, inhibition, induction and effection with nutrients.

Anahtar Kelimeler

• Antioxidant
• detoxification
• liver
• CyP450

Kaynakça

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