Antimicrobial Activity and Chemical Composition of Essential Oil Extracted from Hyoscyamus niger L. Inflorescence

Yıl 2024, Cilt: 17 Sayı: 3, 751 - 760, 31.12.2024

Sefa Gözcü , Zeynep Akşit , Hüseyin Akşit

https://doi.org/10.18185/erzifbed.1522296

Öz

This study aimed to analyze the chemical composition and evaluate the antibacterial activity of essential oils extracted from the H. niger inflorescence collected from Erzincan, Türkiye. The essential oils were extracted using hydrodistillation and analyzed by GC-MS, identifying 23 components, with major constituents being 10-heneicosene (35.72%), phytol (20.50%), and acetic acid, butyl ester (10.10%). The antibacterial activity was tested against six bacterial strains, including Staphylococcus aureus, Clostridium perfringens, Enterococcus faecalis, Bacillus cereus, Listeria monocytogenes, and Escherichia coli, using the disc diffusion method. The H. niger inflorescence essential oil exhibited moderate antibacterial activity, specifically against Clostridium perfringens, with a zone of inhibition of 11.7 ± 1.2 mm compared to the positive control imipenem (17.0±1.0 mm). The results suggest that H. niger inflorescence essential oil has potential as an antibacterial agent, highlighting the importance of exploring plant-derived compounds as alternatives to traditional antibiotics in combating multidrug-resistant bacteria.

Anahtar Kelimeler

Hyoscyamus niger L., Essential oil, Antibacterial, GC-MS

Etik Beyan

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Destekleyen Kurum

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Teşekkür

We thank Professor. Dr. Ali Kandemir for the taxonomic description of the plant samples.

Antimicrobial Activity and Chemical Composition of Essential Oil Extracted from Hyoscyamus niger L. Inflorescence

Öz

Kaynakça

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