PSYCHOBIOTICS: RELATIONSHIP TO DEPRESSION AND ANXIETY

Öz

Psychobiotic sare defined as probiotics that produce positive psychiatric effects when consumed in sufficient quantities. The role of psychobiotics in preventing and even treating some psychological disorders is an is sue that has been emphasized especially in last 10 years. It was stated that psychobiotic bacteria have antidepressant and anxiolytic effects characterized by changes in emotional, cognitive, systemic and neural indexes, and studies on these microorganisms are increasing. In this review, action mechanism of psychobiotics on depression and anxiety, which affect a significant part of the world population, and the clinical studies on this subject were focused on.

Anahtar Kelimeler

• Anxiety
• microbiome
• depression
• probiotic
• psychobiotic

PSİKOBİYOTİKLER: DEPRESYON VE ANKSİYETE İLE İLİŞKİSİ

Öz

Psikobiyotikler, yeterli miktarlarda tüketildiğinde pozitif psikiyatrik etkiler yaratan probiyotikler olarak tanımlanmaktadır. Psikobiyotiklerin bazı psikolojik rahatsızlıkları önleme ve hatta bu hastalıkların tedavi edilmesinde rol oynadıkları özellikle son 10 yılda üzerinde durulan bir konudur. Psikobiyotik bakterilerin duygusal, bilişsel, sistemik ve sinirsel indekslerdeki değişikliklerle karakterize edilen antidepresan ve anksiyolitik etkilere sahip oldukları belirtilmekte ve bu mikroorganizmalar ile ilgili gerçekleştirilen çalışmalar giderek artmaktadır. Bu derlemede psikobiyotiklerin günümüzde dünya nüfusunun önemli bir kısmını etkileyen depresyon ve anksiyete üzerine etki mekanizmaları ile bu konuda gerçekleştirilen klinik çalışmalar üzerinde durulmuştur.

Anahtar Kelimeler

• Anksiyete
• Mikrobiyom
• Depresyon
• Probiyotik
• Psikobiyotik

Kaynakça

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