GIDA AMBALAJI İÇİN BİYOSİDAL ALLİSİN / MT / MMA / PEG / POSS NANOKOMOZİTLERİNİN SENTEZİ VE İN VİTRO SİTOTOKSİSİTE ANALİZİ
Öz
Anahtar Kelimeler
Yüzey aktivitesi biyouyumluluk kurkumin biyopolimerler allisin
Destekleyen Kurum
İstanbul Aydın Üniversitesi
Proje Numarası
27/06/2018-10 (BAP projesi)
Kaynakça
- Söğüt, E., Seydim, A.C. (2017). “Bıo-based Nanocomposıtes and Applıcatıons In Food Packagıng.” Gıda The Journal of Food, 47(6): 821-833. Dag, D., Guner, S., Halil Oztop M. (2019). Physicochemical mechanisms of different biopolymers' (lysozyme, gum arabic, whey protein, chitosan) adsorption on green tea extract loaded liposomes. International Journal of Biological Macromolecules, 138: 473–482 Rostami, M.R., Yousefi, M., Khezerlou, A., Aman Mohammadi, M., Jafari, S.M. (2019). Application of different biopolymers for nanoencapsulation of antioxidants via electrohydrodynamic processes. Food Hydrocolloids, 97: 105170 Baysal, G., and Çelik, B.Y. (2018). Synthesis and characterization of antibacterial bionano films for food packaging. Journal of Envıronmental Scıence and Health Part B, DOİ: 10.1080/03601234.2018.1530546. Dhivya, R., Ranjani, J., Bowen, P. K., Rajendhran, J., Mayandi, J., Annaraj, J. (2017). Biocompatible curcumin loaded PMMA-PEG/ZnO nanocomposite induce apoptosis and cytotoxicity in human gastric cancer cells.” Materials Science and Engineering C, 80:59–68. Özçelik, S., Sümer, Z., Değerli, S., Ozan, F., Sökmen, A. (2007). Garlic (Allium Sativum) Extract Scolocidal can be Used As Agent. Turkey Journal of Parasitology, 31 (4): 318-321. Cheng, H., Huang, G. (2018). Extraction, characterisation and antioxidant activity of Allium sativum polysaccharide. International Journal of Biological Macromolecules, 114: 415–419. Shinzawa,H., Mizukado, J. (2018). Rheo-optical near-infrared (NIR) spectroscopy study of partially miscible polymer blend of polymethyl methacrylate (PMMA) and polyethylene glycol (PEG). Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 192: 236–243. Sohrabnezhad, S., Rassa, M., Mohammadi Dahanesari, E. (2016). Spectroscopic study of silver halides in montmorillonite and their antibacterial activity. Journal of Photochemistry & Photobiology, B: Biology, 163:150–155. Doi:10.1016/j.jphotobiol.2016.08.018. Zhao, F., Wan, C., Bao, X., Kandasubramanian, B. (2009). Modification of montmorillonite with aminopropylisooctyl polyhedral oligomeric Silsequioxane. Journal of Colloid and Interface Science, 333:164–170. Silva, M.N., Fonsecaa, J.M., Feldhaus, H.K., Soares, L.S., Valencia, G.A., Maduro de Campos, C.E., Di Luccio, M., Monteiro. A.R. (2019). Physical and morphological properties of hydroxypropyl methylcellulose films with curcumin polymorphs. Food Hydrocolloids,7: 105217. Philip, P., Tomlal Jose E., Chacko, J K., Philip, K.C., Thomas, P.C. (2019). Preparation and characterisation of surface roughened PMMA electrospun nanofibers from PEO - PMMA polymer blend nanofibers. Polymer Testing, 74: 257–265. Ravindar Reddy, M., Subrahmanyam, A. R., Maheshwar Reddy, M., Siva Kumarc, J., Kamalaker, V., and Jaipal Reddy, M. (2019). X-RD, SEM, FT-IR, DSC Studies of Polymer Blend Films of PMMA and PEO. Materials Today: Proceedings, 3: 3713–3718.. Radha, G., Balakumar, S., Venkatesan, B., Vellaichamy, E. (2017). A novel nano-hydroxyapatite- PMMA hybrid scaffolds adopted by conjugated thermal induced phase separation (TIPS) and wet-chemical approach: Analysis of its mechanical and biological properties. Materials Science and Engineering C, 75: 221–228.. Kang, T., Hua, X., Liang, P., Rao, M., Wang, Q., Quan, C., Zhang, C., Jiang, Q. (2016). Synergistic reinforcement of polydopamine-coated hydroxyapatite and BMP2 biomimetic peptide on the bioactivity of PMMA-based cement. Composites Science and Technology, 123:232-240. Bong Kim, S., Jick Kim, Y., Lim Yoon, T., Park, S.U., Cho, I.H., Kim, E.J., Kima, I.A., Shin, J.W. (2004). The characteristics of a hydroxyapatite–chitosan–PMMA bone cement. Biomaterials, 25: 5715–5723. Marinescu, C., Sofronia, A., Anghel, E.M., Baies, R., Constantin, D., Seciu, A.M., Gingu, O., Tanasescu, S. (2019). Microstructure, stability and biocompatibility of hydroxyapatite -titania nanocomposites formed by two step sintering process. Arabian Journal of Chemistry, 12: 857–867.
IN VITRO CYTOTOXICITY ANALYSIS AND SYNTHESIS OF BIOCIDAL ALLICIN/MT/MMA/PEG/POSS NANOCOMPOSITES FOR THE FOOD PACKAGING
Öz
In this study, the new nanocomposites were synthesized using antibacterial and antioxidant curcumin (Cr) and allicin (Ac), the high mechanical strength montmorillonite clay (Mt) and biocompatible methylmethacrylate (MMA), polyethylene glycol (PEG) and polyocta-hedral oligomeric silsesquioxanes (POSS) polymers. Firstly, monomer 1 was synthesized by using Ag+-montmorillonite, the curcumin extract and POSS, then the synthesized monomer 1 was interacted with MMA and PEG polymers, and nanocomposites were synthesized. The synthesized nanocomposites were analyzed by using the methods of Fourier Transform Infrared Spectroscopy (FTIR), X-ray diffraction (XRD) and scanning electron microscopy (SEM). After this, the inhibition zones and the surface activity resistances of the nanocomposites were analyzed against the bacteria Escherichia coli (E. coli), Listeria monocytogenes (L. monocytogenes), Salmonella and Staphylococcus aureus (S.aureus) and carried out biocompatibility analysis. According to the analysis results, the nanocomposites have been found to have the strong antibacterial resistance and biocompatibility.
Anahtar Kelimeler
Surface activity biocompatibility the curcumin biopolimers the allicin
Proje Numarası
27/06/2018-10 (BAP projesi)
Kaynakça
- Söğüt, E., Seydim, A.C. (2017). “Bıo-based Nanocomposıtes and Applıcatıons In Food Packagıng.” Gıda The Journal of Food, 47(6): 821-833. Dag, D., Guner, S., Halil Oztop M. (2019). Physicochemical mechanisms of different biopolymers' (lysozyme, gum arabic, whey protein, chitosan) adsorption on green tea extract loaded liposomes. International Journal of Biological Macromolecules, 138: 473–482 Rostami, M.R., Yousefi, M., Khezerlou, A., Aman Mohammadi, M., Jafari, S.M. (2019). Application of different biopolymers for nanoencapsulation of antioxidants via electrohydrodynamic processes. Food Hydrocolloids, 97: 105170 Baysal, G., and Çelik, B.Y. (2018). Synthesis and characterization of antibacterial bionano films for food packaging. Journal of Envıronmental Scıence and Health Part B, DOİ: 10.1080/03601234.2018.1530546. Dhivya, R., Ranjani, J., Bowen, P. K., Rajendhran, J., Mayandi, J., Annaraj, J. (2017). Biocompatible curcumin loaded PMMA-PEG/ZnO nanocomposite induce apoptosis and cytotoxicity in human gastric cancer cells.” Materials Science and Engineering C, 80:59–68. Özçelik, S., Sümer, Z., Değerli, S., Ozan, F., Sökmen, A. (2007). Garlic (Allium Sativum) Extract Scolocidal can be Used As Agent. Turkey Journal of Parasitology, 31 (4): 318-321. Cheng, H., Huang, G. (2018). Extraction, characterisation and antioxidant activity of Allium sativum polysaccharide. International Journal of Biological Macromolecules, 114: 415–419. Shinzawa,H., Mizukado, J. (2018). Rheo-optical near-infrared (NIR) spectroscopy study of partially miscible polymer blend of polymethyl methacrylate (PMMA) and polyethylene glycol (PEG). Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 192: 236–243. Sohrabnezhad, S., Rassa, M., Mohammadi Dahanesari, E. (2016). Spectroscopic study of silver halides in montmorillonite and their antibacterial activity. Journal of Photochemistry & Photobiology, B: Biology, 163:150–155. Doi:10.1016/j.jphotobiol.2016.08.018. Zhao, F., Wan, C., Bao, X., Kandasubramanian, B. (2009). Modification of montmorillonite with aminopropylisooctyl polyhedral oligomeric Silsequioxane. Journal of Colloid and Interface Science, 333:164–170. Silva, M.N., Fonsecaa, J.M., Feldhaus, H.K., Soares, L.S., Valencia, G.A., Maduro de Campos, C.E., Di Luccio, M., Monteiro. A.R. (2019). Physical and morphological properties of hydroxypropyl methylcellulose films with curcumin polymorphs. Food Hydrocolloids,7: 105217. Philip, P., Tomlal Jose E., Chacko, J K., Philip, K.C., Thomas, P.C. (2019). Preparation and characterisation of surface roughened PMMA electrospun nanofibers from PEO - PMMA polymer blend nanofibers. Polymer Testing, 74: 257–265. Ravindar Reddy, M., Subrahmanyam, A. R., Maheshwar Reddy, M., Siva Kumarc, J., Kamalaker, V., and Jaipal Reddy, M. (2019). X-RD, SEM, FT-IR, DSC Studies of Polymer Blend Films of PMMA and PEO. Materials Today: Proceedings, 3: 3713–3718.. Radha, G., Balakumar, S., Venkatesan, B., Vellaichamy, E. (2017). A novel nano-hydroxyapatite- PMMA hybrid scaffolds adopted by conjugated thermal induced phase separation (TIPS) and wet-chemical approach: Analysis of its mechanical and biological properties. Materials Science and Engineering C, 75: 221–228.. Kang, T., Hua, X., Liang, P., Rao, M., Wang, Q., Quan, C., Zhang, C., Jiang, Q. (2016). Synergistic reinforcement of polydopamine-coated hydroxyapatite and BMP2 biomimetic peptide on the bioactivity of PMMA-based cement. Composites Science and Technology, 123:232-240. Bong Kim, S., Jick Kim, Y., Lim Yoon, T., Park, S.U., Cho, I.H., Kim, E.J., Kima, I.A., Shin, J.W. (2004). The characteristics of a hydroxyapatite–chitosan–PMMA bone cement. Biomaterials, 25: 5715–5723. Marinescu, C., Sofronia, A., Anghel, E.M., Baies, R., Constantin, D., Seciu, A.M., Gingu, O., Tanasescu, S. (2019). Microstructure, stability and biocompatibility of hydroxyapatite -titania nanocomposites formed by two step sintering process. Arabian Journal of Chemistry, 12: 857–867.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Gıda Mühendisliği |
| Bölüm | Makaleler |
| Yazarlar | |
| Proje Numarası | 27/06/2018-10 (BAP projesi) |
| Yayımlanma Tarihi | 15 Haziran 2020 |
| Yayımlandığı Sayı | Yıl 2020 Cilt: 45 Sayı: 3 |
