A New Hepatotoxic Agent : Goji Berry
Öz
ABSTRACT
INTRODUCTION: Goji berry has long been used as a healthy aliment for healthy vision, strengthening the immune system, protecting the liver, improving circulation, remedy for diabetes, enhancing sexual performance and general health. But there are not enough study on its constituents, pharmacology and safety.
CASE REPORT: This case report describes a 24-year-old female patient was admitted to emergency service due to complaints of nausea, vomiting and abdominal pain. Ictherus at sclera and sensivitiy on the right upper quadrant of abdomen were found on the physical examination. Blood tests revealed high liver function tests. The causes of jaundice and impaired liver function were all excluded and toxic hepatitis due to goji berry consumption was considered in patient.
CONCLUSION: Goji berry is a traditional nutrient that is increasingly used for its various effects. To date, there are some articles declared allergic reactions as toxic effect. To our knowledge this case is the first publication that goji berries can be toxic to the liver. Although larger studies are required, it should be kept in mind that liver toxicity may occur during intensive use.
Anahtar Kelimeler
Kaynakça
- Catherine Ulbricht et al. An Evidence-Based Systematic Review of Goji (Lycium spp.) by the Natural Standard Research Collaboration, Journal of Dietary Supplements (2015),12:2, 184-240.
- Amagase H, Nance DM. Lycium barbarum increases caloric expenditure and decreases waist circumference in healthy overweight men and women: pilot study. J Am Coll Nutr. 2011;30(5):304–309.
- Yu MS, Ho YS, So KF, Yuen WH, Chang RC. Cytoprotective effects ofLycium barbarum against reducing stress on endoplasmic reticulum. Int J Mol Med. 2006;17(6):1157–1161.
- Larramendi, C.H., García-Abujeta, J.L., Vicario, S. et al, Goji berries (Lycium barbarum): risk of allergic reactions in individuals with food allergy. J Investig Allergol Clin Immunol. 2012;22:345–350.
- Daniela Zauli, Maria Grazia Mirarchi. Anaphylaxis induced by Goji berries. Ann Allergy Asthma Immunol. 2015;114: 535-536.
- S Monzón Ballarín, MA López-Matas, D Sáenz Abad, N Pérez-Cinto, J Carnés. Anaphylaxis Associated With the Ingestion of Goji Berries (Lycium barbarum). J Investig Allergol Clin Immunol 2011; Vol. 21(7): 567-570
- Potterat O. Goji (Lycium barbarum and L. chinense): phytochemistry, pharmacology and safety in the perspective of traditional uses and recent popularity. Planta Med. 2010;76(1):7–19.
- Rivera CA, Ferro CL, Bursua AJ, Gerber BS. Probable interaction between Lycium barbarum (goji) and warfarin. Pharmacotherapy. 2012;32(3):e50–e53.
Ayrıntılar
Birincil Dil
İngilizce
Konular
Klinik Tıp Bilimleri
Bölüm
Olgu Sunumu
Yazarlar
Kıvanç Karaman
*
0000-0002-4105-2785
Türkiye
Yunus Emre Özlüer
0000-0001-8297-7525
Türkiye
Ahmet Tunç Deniz
0000-0003-2240-1270
Türkiye
Yayımlanma Tarihi
1 Ekim 2019
Gönderilme Tarihi
24 Ocak 2019
Kabul Tarihi
22 Ağustos 2019
Yayımlandığı Sayı
Yıl 2019 Cilt: 10 Sayı: 4