The Effect of Creatin on Athletes

Öz

Creatine, an amino acid, is one of the most commonly used ergogenic supplements and is not considered doping. Creatine type-2 is stored in fast-twitch fibers, and the increase in muscle performance by creatine loading, which increases the biological formation of phosphocreatine (PCr), which is the storage form in muscles, in muscle cells, is explained by various mechanisms. Although no side effects are observed when used in appropriate doses, there is a risk of dehydration due to its osmotic effect, and therefore plenty of fluid consumption is recommended. It is claimed to have many positive effects on athletes. It is recommended to increase performance, especially for short-term, high-intensity exercises and anaerobic exercises. The results of creatine on athletes may vary in different sports branches and according to different supplementation protocols. The state of initial creatine stores affects the muscle creatine increase that will occur after supplementation. There are conflicting results regarding creatine supplementation in studies conducted on veteran athletes who are generally over the age of forty and exercise regularly. Studies using creatine supplements show results showing increases in both lean body mass and fat mass. Although studies on creatine supplementation have yielded results regarding its short-term effects, long-term results remain unclear.

Anahtar Kelimeler

• Creatin
• ergogenic performance
• athlete
• exercise
• sports nutrition

Kreatinin Sporcular Üzerindeki Etkisi

Öz

Bir aminoasit olan kreatin, en sık kullanılan ergojenik desteklerden birisidir ve doping sayılmamaktadır. Kreatin tip-2 hızlı kasılan liflerde depo edilir ve kaslarda depolanma formu olan fosfokreatinin (PCr) kas hücrelerindeki biyolojik oluşumu arttıran kreatin yüklemesi ile kas performansındaki artış çeşitli mekanizmalarla açıklanmaktadır. Uygun dozda kullanımında yan etki gözlemlenmese de ozmotik etkisinden dolayı dehidratasyon riski bulunmaktadır ve bu sebeple bol sıvı tüketimi önerilmektedir. Sporcular üzerine birçok olumlu etkisi olduğu iddia edilmektedir. Özellikle kısa süreli, yüksek şiddetli egzersizler ve anaerobik egzersizler için performansı arttırmak için önerilmektedir. Farklı spor dallarında, farklı takviye protokollerine göre, kreatinin sporcu üzerindeki elde edilen sonuçları farklılık gösterebilmektedir. Başlangıçtaki kreatin depolarının durumu, takviye sonrası gerçekleşecek kas kreatin artışını etkilemektedir. Kreatin takviyesi ile ilgili genellikle kırk yaş üzeri olan ve düzenli egzersiz yapan veteran sporcular üzerine yapılan çalışmalarda çelişkili sonuçlar bulunmaktadır. Kreatin takviyesi yapılan çalışmalarda hem yağsız vücut kütlesini hem de yağ kütlesinde artışlar olduğunu gösteren sonuçlar bulunmaktadır. Kreatin takviyesi üzerine yapılan çalışmalarda kısa süreli etkilerine dair sonuçlar elde edilmiş olsa da uzun dönemde gerçekleşecek sonuçlar belirsizliğini korumaktadır.

Anahtar Kelimeler

• Kreatin
• ergojenik destek
• performans
• egzersiz
• sporcu beslenmesi

Kaynakça

1. Referans1. Şemşek, Ö., Yüktaşır, B., & Şemşek, S. Ergojenik Yardımcı Olarak Kullanılan Besin Suplementleri. Beden Eğitimi ve Spor Bilimleri Dergisi, 1(3).
2. Referans2. Karakuş, M. (2014). Sporcularda Ergojenik Destek. Spor Hekimliği Dergisi, 49(4), 155-167.
3. Referans3. Butts, J., Jacobs, B., & Silvis, M. (2018). Creatine Use in Sports. Sports Health, 10(1), 31– 34. Https://Doi.Org/10.1177/1941738117737248
4. Referans4. Bayram, H. M., & Öztürkcan, S. A. (2020). Sporcularda Ergojenik Destekler. Turkiye Klinikleri Journal Of Health Sciences, 5(3).
5. Referans5. Poortmans, J. R., & Francaux, M. (1999). Long-Term Oral Creatine Supplementation Does Not Impair Renal Function in Healthy Athletes. Medicine And Science in Sports And Exercise, 31(8), 1108-1110.
6. Referans6. Kreider, R.B.; Kalman, D.S.; Antonio, J.; Ziegenfuss, T.N.; Wildman, R.; Collins, R.; Candow, D.G.; Kleiner, S.M.; Almada, A.L.; Lopez, H.L. International Society Of Sports Nutrition Position Stand: Safety And Efficacy Of Creatine Supplementation in Exercise, Sport, And Medicine. J. Int. Soc. Sports Nutr. 2017, 14, 1–18
7. Referans7. Eckerson Jm., Bull Aa., Moore Ga. (2008). Effect Of Thirty Days Of Creatine Supplementation With Phosphate Salts On Anaerobic Working Capacity And Body Weight in Man. Journal Of Strength And Conditioning Research. 22(3), 826-832.)
8. Referans8. Wax, B., Kerksick, C. M., Jagim, A. R., Mayo, J. J., Lyons, B. C., & Kreider, R. B. (2021). Creatine For Exercise And Sports Performance, With Recovery Considerations For Healthy Populations. Nutrients, 13(6), 1915. Https://Doi.Org/10.3390/Nu13061915

9. Referans9. Hall, M., & Trojian, T. H. (2013). Creatine Supplementation. Current Sports Medicine Reports, 12(4), 240-244.
10. Referans10. Shao, A., & Hathcock, J. N. (2006). Risk Assessment For Creatine Monohydrate. Regulatory Toxicology And Pharmacology, 45(3), 242-251.
11. Referans11. Eskici, G. (2015). Takım Sporlarında Beslenme. International Journal Of Human Sciences, 12(2), 244-265. 10.14687/İjhs.V12i2.3190
12. Referans12. Mielgo-Ayuso, J., Calleja-Gonzalez, J., Marqués-Jiménez, D., Caballero-García, A., Córdova, A., & Fernández-Lázaro, D. (2019). Effects Of Creatine Supplementation On Athletic Performance in Soccer Players: A Systematic Review And Meta-Analysis. Nutrients, 11(4), 757. Https://Doi.Org/10.3390/Nu11040757
13. Referans13. Kreider, R. B., Kalman, D. S., Antonio, J., Ziegenfuss, T. N., Wildman, R., Collins, R., Candow, D. G., Kleiner, S. M., Almada, A. L., & Lopez, H. L. (2017). International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine. Journal of the International Society of Sports Nutrition, 14, 18. https://doi.org/10.1186/s12970-017-0173-z
14. Referans14. Wang, C. C., Yang, M. T., Lu, K. H., & Chan, K. H. (2016). The Effects Of Creatine Supplementation On Explosive Performance And Optimal Individual Postactivation Potentiation Time. Nutrients, 8(3), 143. Https://Doi.Org/10.3390/Nu8030143
15. Referans15. del Favero, S., Roschel, H., Artioli, G., Ugrinowitsch, C., Tricoli, V., Costa, A., Barroso, R., Negrelli, A. L., Otaduy, M. C., da Costa Leite, C., Lancha-Junior, A. H., & Gualano, B. (2012). Creatine but not betaine supplementation increases muscle phosphorylcreatine content and strength performance. Amino acids, 42(6), 2299–2305. https://doi.org/10.1007/s00726-011-0972-5
16. Referans16. Lee Cl., Lin Jc., Cheng Cf. (2011). Effect Of Caffeine Ingestion After Creatine Supplementation On Intermittent High-Intensity Sprint Performance. European Journal Of Applied Physiology. 111(8), 1669-1677.
17. Referans17. Brudnak Ma. (2004). Creatine: Are The Benefits Worth The Risk? Toxicol Letters. 150(1), 123-130.
18. Referans18. Kreider, R. B., Wilborn, C. D., Taylor, L., Campbell, B., Almada, A. L., Collins, R., Cooke, M., Earnest, C. P., Greenwood, M., Kalman, D. S., Kerksick, C. M., Kleiner, S. M., Leutholtz, B., Lopez, H., Lowery, L. M., Mendel, R. Smith, A., Spano, M., Wildman, R., Willoughby, D., Ziegenfuss, T. N. & Antonio, J. (2010). Issn Exercise & Sport Nutrition Review: Research & Recommendations. Journal Of The İnternational Society Of Sports Nutrition, 7(1), 7.
19. Referans19. Buford, T. W., Kreider, R. B., Stout, J. R., Greenwood, M., Campbell, B., Spano, M., Ziegenfuss, T., Lopez, H., Landis, J., & Antonio, J. (2007). International Society of Sports Nutrition position stand: creatine supplementation and exercise. Journal of the International Society of Sports Nutrition, 4, 6. https://doi.org/10.1186/1550-2783-4-6
20. Referans20. Kerksick, C.M., Wilborn, C.D., Roberts, M.D., Smith-Ryan, A., Kleiner, S.M., Jäger, R., Collins, R., Cooke, M., Davis, J.N., Galvan, E., Greenwood, M., Lowery, L.M., Wildman, R., Antonio, J. & Kreider, R.B. (2018). Issn Exercise & Sports Nutrition Review Update: Research & Recommend. Journal Of The International Society Of Sports Nutrition, 15, 38. 10.1186/S12970-018-0242-Y.
21. Referans21. Çelik, G., Bayram, H. M., & Ozturkcan, A. (2021). Ergojenik Destekler: Özel Bir Grup" Veteran Sporcular". Ulusal Spor Bilimleri Dergisi, 5(1), 104-121.
22. Referans22. Eijnde, B.O., Leemputte, M.V., Goris, M., Labarque, V., Taes, Y., Verbessem, P., Vanhees, L., Ramaekers, M., Eynde, B.V., Schuylenbergh, R.V., Dom, R., Richter, E.A. & Hespel, P. (2003). Effects Of Creatine Supplementation And Exercise Training On Fitness in Men 55-75 Yr Old. Journal Of Applied Physiology, 95(2), 818–28: 10.1152/Japplphysiol.00891.2002.
23. Referans23. Brose, A., Parise, G. & Tarnopolsky, M.A. (2003). Creatine Supplementation Enhances İsometric Strength And Body Composition Improvements Following Strength Exercise Training in Older Adults. Journal Of Gerontology: Biological Sciences And The Journal Of Gerontology: Medical Sciences, 58(1), 11-9. 10.1093/Gerona/58.1.B11.
24. Referans24. Aguiar, A.F., Januário, R.S.B., Junior, R.P., Gerage, A.M., Pina, F.L.C., Do Nascimento, M.A., Padovani, C.R. & Cyrino, E.S. (2013). Long-Term Creatine Supplementation Improves Muscular Performance During Resistance Training in Older Women. European Journal Of Applied Physiology,113(4), 987–96. 10.1007/S00421-012-2514-6.
25. Referans25. Candow, D.G., Little, J.P., Chilibeck, P.D., Abeysekara, S., Zello, G.A., Kazachkov, M., Cornish, S.M. & Yu, P.H. (2008). Low-Dose Creatine Combined With Protein During Resistance Training in Older Men. Medicine & Science in Sports & Exercise, 40(9), 1645–52. 10.1249/Mss.0b013e318176b310.
26. Referans26. Cooke, M. B., Rybalka, E., Williams, A. D., Cribb, P. J., & Hayes, A. (2009). Creatine Supplementation Enhances Muscle Force Recovery After Eccentrically-İnduced Muscle Damage İn Healthy İndividuals. Journal Of The International Society Of Sports Nutrition, 6(1), 13.
27. Referans27. Zuniga, J. M., Housh, T. J., Camic, C. L., Hendrix, C. R., Mielke, M., Johnson, G. O., Housh, D. J., & Schmidt, R. J. (2012). The effects of creatine monohydrate loading on anaerobic performance and one-repetition maximum strength. Journal of strength and conditioning research, 26(6), 1651–1656. https://doi.org/10.1519/JSC.0b013e318234eba1
28. Referans28. Lanhers, C., Pereira, B., Naughton, G., Trousselard, M., Lesage, F. X., & Dutheil, F. (2015). Creatine Supplementation And Lower Limb Strength Performance: A Systematic Review And Meta-Analyses. Sports Medicine, 45, 1285-1294.
29. Referans29. De Salles Painelli, V., Alves, V. T., Ugrinowitsch, C., Benatti, F. B., Artioli, G. G., Lancha, A. H., ... & Roschel, H. (2014). Creatine Supplementation Prevents Acute Strength Loss Induced By Concurrent Exercise. European Journal Of Applied Physiology, 114(8), 1749- 1755.
30. Referans30. Wang, C. C., Fang, C. C., Lee, Y. H., Yang, M. T., & Chan, K. H. (2018). Effects Of 4- Week Creatine Supplementation Combined With Complex Training On Muscle Damage And Sport Performance. Nutrients, 10(11), 1640.
31. Referans31. Manjarrez-Montes De Oca Manjarrez-Montes De Oca, R., Farfán-González, F., Camarillo- Romero, S., Tlatempa-Sotelo, P., Francisco-Argüelles, C., Kormanowski, A., González- Gallego, J., & Alvear-Ordenes, I. (2013). Effects Of Creatine Supplementation in Taekwondo Practitioners. Nutricion Hospitalaria, 28(2), 391–399. Https://Doi.Org/10.3305/Nh.2013.28.2.6314
32. Referans32. Ahmet, M. O. R., İpekoğlu, G., Baynaz, K., Arslanoğlu, C., Kürşat, A. C. A. R., & Arslanoğlu, E. Futbolcularda Bcaa Ve Kreatin Alımının Vücut Kompozisyonu Üzerine Etkisi. Beden Eğitimi Ve Spor Bilimleri Dergisi, 13(3), 274-285.
33. Referans33. Jones, A. M., Atter, T., & Georg, K. P. (1999). Oral Creatine Supplementation Improves Multiple Sprint Performance in Elite Ice-Hockey Players. Journal Of Sports Medicine And Physical Fitness, 39(3), 189.
34. Referans34. Pluim, B. M., Ferrauti, A., Broekhof, F., Deutekom, M., Gotzmann, A., Kuipers, H., & Weber, K. (2006). The Effects Of Creatine Supplementation On Selected Factors Of Tennis Specific Training. British Journal Of Sports Medicine, 40(6), 507–512. Https://Doi.Org/10.1136/Bjsm.2005.022558.
35. Referans35. Devries, M. C., & Phillips, S. M. (2014). Creatine Supplementation During Resistance Training in Older Adults—A Meta-Analysis. Medicine & Science in Sports & Exercise, 46(6), 1194-1203