BibTex RIS Kaynak Göster

Should Hysterosalpingography Routinely Or Selectively Performed As A First Step İn The Evaluation Of İnfertile Couples?

Yıl 2017, Cilt: 14 Sayı: 3, 114 - 117, 01.07.2017

Öz

Aim: Routine hysterosalpingography HSG in the evaluation of infertile couples is still a subject of discussion. Whereas some of the professional organizations recommend performing HSG to all patients, other authors recommend performing it selectively. We aimed to assess whether risk factors in medical history might predict the presence of tubal disease on HSG.Material and methods: Five-hundred and fifty-three patients whom were assessed with HSG between January-2010 and December-2012 in Department of OBGYN, Hacettepe University were enrolled. Of them, images of 423 cases were sufficient for further evaluation. The pathologies those are observed with HSG were stratified according to the location as uterine, tubal, both tubal and uterine diseases. Meanwhile, all patients were questioned by telephone about Pelvic Inflammatory Disease PID symptoms and previous pelvic surgery.Results: Of 423 women, no pathology was noticed in 47.8% of them n= 202 . We were able reach 208 of 423 subjects by phone and 48 23.1% of them had a history of previous PID attack. Among patients having significant symptoms for PID, while 50.0% had normal HSG, 33.3% had tubal-only, 8.3% had uterine-only, and 8.3% had both tubal and uterine diseases on HSG. Patients without a history of PID, the respective figures for normal, uterine-only, tubal-only and both uterine and tubal diseases were 50.0%, 17.8%, 27.5% and 5.0% on HSG p > 0.05 for all comparisons . A presence of previous pelvic surgery was significantly more prevalent among the patients with abnormal HSG findings 42.3% vs. 28.8%, p=0.042 and it remained to be significant predictor for abnormal findings on HSG along with female age in the logistic regression analysis.Conclusion: Even among patients who do not have risk factors for tubal disease, considerable amount of tubal pathology is still determined via HSG. Since some attacks remain subclinical, the underestimation of the prevalence of PID might be responsible for that conclusion. Therefore, only screening for risk factors related with tubal disease might not be ideal before deciding to perform uterine-tubal imaging or not. Whereas increasing female age and presence of previous pelvic surgery might be independent predictors for abnormal HSG findings.

Kaynakça

  • Evers, J.L., Female subfertility. Lancet, 2002. 360(9327): p. 151-9.
  • Practice Committee of the American Society for Reproductive Medicine. Diagnostic evaluation of the infertile female: a committee opinion. Fertil Steril, 2015. 103(6): p. e44-50.
  • Fritz, M.A. and L. Speroff, Clinical Gynecologic Endocrinology and Infer- tility, 8th Edition. 8 ed, ed. L. Speroff. 2010, Philadelphia, USA: Lippincott Williams & Wilkins.
  • The Practice Committee of the American Society for Reproductive Me- dicine, Optimal evaluation of the infertile female. Fertility and Sterility, 2006. 86(5, Supplement): p. S264-S267.
  • Mohiyiddeen L, Hardiman A, Fitzgerald C, Hughes E, Mol BW, Johnson N, et al., Tubal flushing for subfertility. Cochrane Database Syst Rev, 2015. 5: p. CD003718.
  • Swart P, Mol BW, van der Veen F, van Beurden M, Redekop WK, Bossuyt PM. The accuracy of hysterosalpingography in the diagnosis of tubal pathology: a meta-analysis. Fertil Steril, 1995. 64(3): p. 486-91.
  • Anserini P, Delfino F, Ferraiolo A, Remorgida V, Menoni S, De Caro G. Strategies to minimize discomfort during diagnostic hysterosalpingog- raphy with disposable balloon catheters: a randomized placebo-control- led study with oral nonsteroidal premedication. Fertil Steril, 2008. 90(3): p. 844-8.
  • Saunders, R.D., J.M. Shwayder, and S.T. Nakajima, Current methods of tubal patency assessment. Fertil Steril, 2011. 95(7): p. 2171-9.
  • Holz, K., R. Becker, and R. Schurmann, Ultrasound in the investigation of tubal patency. A meta-analysis of three comparative studies of Echo- vist-200 including 1007 women. Zentralbl Gynakol, 1997. 119(8): p. 366-73.
  • Maheux-Lacroix S1, Boutin A, Moore L, Bergeron ME, Bujold E, Laberge P, et al., Hysterosalpingosonography for diagnosing tubal occlusion in subfertile women: a systematic review with meta-analysis. Hum Reprod, 2014. 29(5): p. 953-63.
  • Mol BW, Dijkman B, Wertheim P, Lijmer J, van der Veen F, Bossuyt PM. The accuracy of serum chlamydial antibodies in the diagnosis of tubal pathology: a meta-analysis. Fertil Steril, 1997. 67(6): p. 1031-7.
  • Gijsen AP1, Land JA, Goossens VJ, Leffers P, Bruggeman CA, Evers JL., Chlamydia pneumoniae and screening for tubal factor subfertility. Hum Reprod, 2001. 16(3): p. 487-91.
  • den Hartog, J.E., S.A. Morre, and J.A. Land, Chlamydia trachomatis-as- sociated tubal factor subfertility: Immunogenetic aspects and serological screening. Hum Reprod Update, 2006. 12(6): p. 719-30.
  • Mol BW1, Collins JA, Van Der Veen F, Bossuyt PM, Cost-effectiveness of hysterosalpingography, laparoscopy, and Chlamydia antibody testing in subfertile couples. Fertil Steril, 2001. 75(3): p. 571-80.
  • Women’s, N.C.C.f. and C.s. Health, Fertility: assessment and treatment for people with fertility problems. 2013.
  • Coppus SF1, Verhoeve HR, Opmeer BC, van der Steeg JW, Steures P, Eijkemans MJ, et al., Identifying subfertile ovulatory women for timely tubal patency testing: a clinical decision rule based on medical history. Human reproduction, 2007. 22(10): p. 2685-2692.
  • Coppus SF1, Verhoeve HR, Opmeer BC, van der Steeg JW, Steures P, Eijkemans MJ, et al., Identifying subfertile ovulatory women for timely tubal patency testing: a clinical decision rule based on medical history. Human reproduction, 2007. 22(10): p. 2685-2692
  • Zhao, W.H . and M. Hao, Pelvic inflammatory disease: a retrospective clinical analysis of 1,922 cases in North China. Gynecol Obstet Invest, 2014. 77(3): p. 169-75.
  • Moore DE, Spadoni LR, Foy HM, Wang SP, Daling JR, Kuo CC, et al., Increased frequency of serum antibodies to Chlamydia trachomatis in infertility due to distal tubal disease. Lancet, 1982. 2(8298): p. 574-7.
  • Luttjeboer FY, Verhoeve HR, van Dessel HJ, van der Veen F, Mol BW, Cop- pus SF., The value of medical history taking as risk indicator for tubope- ritoneal pathology: a systematic review. Bjog, 2009. 116(5): p. 612-25.
  • Rozewicki, S., A. Niedzielski, and W. Bielewicz, Diagnostic value of dire- cted anamnesis and gynecologic examination with regard to HSG investi- gation in diagnosis of mechanical infertility in women. Ginekol Pol, 1992. 63(10): p. 507-11.

İnfertil Çiftin İlk Basamak Değerlendirmesinde Histerosalpingografi Rutin Herkese Mi Veya Seçilmiş Hastalara Mı Yapılmalı?

Yıl 2017, Cilt: 14 Sayı: 3, 114 - 117, 01.07.2017

Öz

Amaç: İnfertil çiftin değerlendirilmesinde rutin histerosalpingografi HSG yeri hala tartışma konusudur. Bazı dernekler bültenlerinde HSG’nin tüm hastalara rutin olarak yapılmasını önerirken buna karşın bazı yazarlarda seçilmiş hastalarda uygulanmasını önermektedir. Biz çalışmamızda kadının medikal öyküsündeki risk faktörlerinin HSG’de tubal patoloji varlığını öngörebilip öngöremeyeceğini araştırmayı amaçladık.Gereç ve Yöntemler: Çalışmaya Ocak 2010 – Aralık 2012 tarihleri arasında Hacettepe Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum Anabilim Dalında HSG çekilen 553 kadın dahil edildi. Bu HSG’lerin 423 tanesi ileri değerlendirme için uygun yeterlilikte bulundu. HSG’deki patolojiler yerine göre tubal, uterine ve hem tubal hem uterin patoloji şeklinde gruplandırıldı. Aynı zamanda çalışmaya dahil edilen bu hastalar telefon ile aranarak pelvik inflamatuar hastalık PID ve geçirilmiş pelvik cerrahi yönünden sorgulandı.Bulgular: Değerlendirilen 423 kadın arasından %47.8’inde n=202 herhangi bir patolojiye rastlanılmadı. Telefon ile yapılan ankete 423 hastanın 208 tanesi katıldı ve bunların 48 %23.1 tanesinin hikayesinde geçirilmiş PID atağı saptandı. PID semptomları olan kadınların %50.0’sinin HSG’si normalken %33.3’ünün sadece tubal patoloji, %8.3’nün sadece uterin patolojisi ve %8.3’nün hem uterin hem tubal patolojisi vardı. PID semptomu olmayan hastalarda bu durum sırasıyla %50.0, 27.5%, %17.8 ve %5.0’idi ve tüm karşılaştırmalar istatistiksel olarak anlamsızdı. Diğer yandan anormal HSG’si olan kadınlar arasında geçirilmiş pelvik cerrahinin istatistiksel anlamlı olarak daha sık olduğu gözlendi ve lojistik regresyon analizinde de artan kadın yaşı ile birlikte geçirilmiş pelvik cerrahinin HSG’de anormal bulgular için bağımsız birer belirteç olduğu saptandı.Sonuç: Medikal hikayesinde tubal hastalık yönünden risk faktörü olmayan kadınlar arasında bile HSG’de hala hatırı sayılır derecede patolojiye rastlanılmaktadır. Bazı ataklar subklinik kalabileceğinden PID sıklığının azımsanması bu sonuçların nedeni olabilir. Bu nedenle uterin ve tubal görüntüleme yapılıp yapılmayacağına sadece tubal hastalık ile ilgili risk faktörleri varlığına göre karar vermek ideal olmayabilir. Buna karşın ilerleyen kadın yaşı ve geçirilmiş pelvik cerrahinin varlığı da anormal HSG bulguları yönünden bağımız belirteç olabilir.

Kaynakça

  • Evers, J.L., Female subfertility. Lancet, 2002. 360(9327): p. 151-9.
  • Practice Committee of the American Society for Reproductive Medicine. Diagnostic evaluation of the infertile female: a committee opinion. Fertil Steril, 2015. 103(6): p. e44-50.
  • Fritz, M.A. and L. Speroff, Clinical Gynecologic Endocrinology and Infer- tility, 8th Edition. 8 ed, ed. L. Speroff. 2010, Philadelphia, USA: Lippincott Williams & Wilkins.
  • The Practice Committee of the American Society for Reproductive Me- dicine, Optimal evaluation of the infertile female. Fertility and Sterility, 2006. 86(5, Supplement): p. S264-S267.
  • Mohiyiddeen L, Hardiman A, Fitzgerald C, Hughes E, Mol BW, Johnson N, et al., Tubal flushing for subfertility. Cochrane Database Syst Rev, 2015. 5: p. CD003718.
  • Swart P, Mol BW, van der Veen F, van Beurden M, Redekop WK, Bossuyt PM. The accuracy of hysterosalpingography in the diagnosis of tubal pathology: a meta-analysis. Fertil Steril, 1995. 64(3): p. 486-91.
  • Anserini P, Delfino F, Ferraiolo A, Remorgida V, Menoni S, De Caro G. Strategies to minimize discomfort during diagnostic hysterosalpingog- raphy with disposable balloon catheters: a randomized placebo-control- led study with oral nonsteroidal premedication. Fertil Steril, 2008. 90(3): p. 844-8.
  • Saunders, R.D., J.M. Shwayder, and S.T. Nakajima, Current methods of tubal patency assessment. Fertil Steril, 2011. 95(7): p. 2171-9.
  • Holz, K., R. Becker, and R. Schurmann, Ultrasound in the investigation of tubal patency. A meta-analysis of three comparative studies of Echo- vist-200 including 1007 women. Zentralbl Gynakol, 1997. 119(8): p. 366-73.
  • Maheux-Lacroix S1, Boutin A, Moore L, Bergeron ME, Bujold E, Laberge P, et al., Hysterosalpingosonography for diagnosing tubal occlusion in subfertile women: a systematic review with meta-analysis. Hum Reprod, 2014. 29(5): p. 953-63.
  • Mol BW, Dijkman B, Wertheim P, Lijmer J, van der Veen F, Bossuyt PM. The accuracy of serum chlamydial antibodies in the diagnosis of tubal pathology: a meta-analysis. Fertil Steril, 1997. 67(6): p. 1031-7.
  • Gijsen AP1, Land JA, Goossens VJ, Leffers P, Bruggeman CA, Evers JL., Chlamydia pneumoniae and screening for tubal factor subfertility. Hum Reprod, 2001. 16(3): p. 487-91.
  • den Hartog, J.E., S.A. Morre, and J.A. Land, Chlamydia trachomatis-as- sociated tubal factor subfertility: Immunogenetic aspects and serological screening. Hum Reprod Update, 2006. 12(6): p. 719-30.
  • Mol BW1, Collins JA, Van Der Veen F, Bossuyt PM, Cost-effectiveness of hysterosalpingography, laparoscopy, and Chlamydia antibody testing in subfertile couples. Fertil Steril, 2001. 75(3): p. 571-80.
  • Women’s, N.C.C.f. and C.s. Health, Fertility: assessment and treatment for people with fertility problems. 2013.
  • Coppus SF1, Verhoeve HR, Opmeer BC, van der Steeg JW, Steures P, Eijkemans MJ, et al., Identifying subfertile ovulatory women for timely tubal patency testing: a clinical decision rule based on medical history. Human reproduction, 2007. 22(10): p. 2685-2692.
  • Coppus SF1, Verhoeve HR, Opmeer BC, van der Steeg JW, Steures P, Eijkemans MJ, et al., Identifying subfertile ovulatory women for timely tubal patency testing: a clinical decision rule based on medical history. Human reproduction, 2007. 22(10): p. 2685-2692
  • Zhao, W.H . and M. Hao, Pelvic inflammatory disease: a retrospective clinical analysis of 1,922 cases in North China. Gynecol Obstet Invest, 2014. 77(3): p. 169-75.
  • Moore DE, Spadoni LR, Foy HM, Wang SP, Daling JR, Kuo CC, et al., Increased frequency of serum antibodies to Chlamydia trachomatis in infertility due to distal tubal disease. Lancet, 1982. 2(8298): p. 574-7.
  • Luttjeboer FY, Verhoeve HR, van Dessel HJ, van der Veen F, Mol BW, Cop- pus SF., The value of medical history taking as risk indicator for tubope- ritoneal pathology: a systematic review. Bjog, 2009. 116(5): p. 612-25.
  • Rozewicki, S., A. Niedzielski, and W. Bielewicz, Diagnostic value of dire- cted anamnesis and gynecologic examination with regard to HSG investi- gation in diagnosis of mechanical infertility in women. Ginekol Pol, 1992. 63(10): p. 507-11.
Toplam 21 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Research Article
Yazarlar

Sezcan Mümüşoğlu

Aslıhan Yazıcıoğlu Bu kişi benim

Özge Senem Yücel Bu kişi benim

Dila Zengin Kasapoglu Bu kişi benim

Gürkan Bozdağ Bu kişi benim

Yayımlanma Tarihi 1 Temmuz 2017
Yayımlandığı Sayı Yıl 2017 Cilt: 14 Sayı: 3

Kaynak Göster

Vancouver Mümüşoğlu S, Yazıcıoğlu A, Yücel ÖS, Zengin Kasapoglu D, Bozdağ G. Should Hysterosalpingography Routinely Or Selectively Performed As A First Step İn The Evaluation Of İnfertile Couples?. JGON. 2017;14(3):114-7.