TWO CASES OF PERINATAL HIV AND LITERATURE REVIEW

Yıl 2018, Cilt 19, Sayı 4, 153 - 156, 26.10.2018

Fatma Hilal YILMAZ Nazlı Dilay GÜLTEKİN Saime SÜNDÜZ UYGUN Hüseyin ALTUNHAN

https://doi.org/10.18229/kocatepetip.475021

Öz

Already existing in 37 million people worldwide,

human immunodeficiency virus (HIV) tends to

affect more people and, thus, it has become

a significant health problem. Turkey is one

of the countries where HIV infection is rarely

seen. Transmission is vertical at %90 of HIV (+)

infants and perinatal transmission of HIV has

been reduced to less than 1% with the use of

antiretroviral drugs. The risk of complications

related with this prophylactic treatment

might be accepted when relatively higher

morbidity and mortality of HIV infection is

considered. Meanwhile close follow-up of

patients is required due to possible toxicity.

The transmission of HIV into newborns can be

prevented with appropriate management of

the perinatal period. This report describes the

perinatal management of two newborns that

were delivered by HIV (+) mothers.

Anahtar Kelimeler

Fetomaternal infection transmission, human immunodeficiency virus, newborn

İKİ PERİNATAL HİV OLGUSU VE LİTERATÜRÜN GÖZDEN GEÇİRİLMESİ

Öz

Dünya genelinde hâlihazırda yaklaşık 37 milyon

kişide bulunan kazanılmış immün yetersizlik virüsü

(HIV) giderek daha fazla sayıda insanı etkilemekte

ve bu nedenle, önemli bir sağlık

sorunu olarak kabul edilmektedir. Türkiye ise

HIV’in az görüldüğü ülkeler arasında yer

almaktadır. Çocukluk çağı HIV olgularının

%90’ından perinatal yolla geçiş sorumludur ve

antiretroviral profilaksi ile geçiş riski %1’in

altına düşürülmüştür. HIV enfeksiyonunun

mortalite ve morbiditesi düşünüldüğü vakit

koruyucu tedavinin komplikasyonları göze

alınabilir fakat olası toksisite yönünden

hastaların yakın izlemi gerekmektedir. HIV

olgularının engellenmesi büyük oranda perinatal

sürecin doğru yönetimiyle mümkündür.

Burada HIV pozitif annelerden doğmuş olan iki

olgu incelenmiş ve literatür eşliğinde perinatal

yönetim süreci gözden geçirilmiştir.

Anahtar Kelimeler

Fetomaternal enfeksiyon transmisyonu, İnsan immunoyetmezlik virüsü, Yenidoğan

Kaynakça

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