A Rare İncidental Case: Pigmented Neuroendocrine Tumor of Appendix

Öz

Neuroendocrin tumors are one of the most common tumors of the appendix. It is difficult to differantiate acute appendicitis from appendiceal neuroendocrine tumors. 80%  of these tumors are located in tip of the appendix and 95% are measured smaller than 2 cm in diameter. Pigmentation is rare in neuroendocrine carcinomas. Here we report a case of pigmented neuroendocrine tumor which was detected incidentally. 

Anahtar Kelimeler

• appendix,neuroendocrine,pigment

Insidental Saptanan Nadir bir Olgu: Apendikste Pigmente Nöroendokrin Tümör

Öz

Nöroendokrin tümörler apendiksin sık görülen tümörleridir. Klinik olarak apendiksin nöroendokrin tümörlerinin akut apendisitten ayırımı mümkün değildir. Tümörlerin %80’i tip yerleşimli ve %95’i 2cm’den küçük çaptadır. Nöroendokrin tümörlerde pigmentasyon oldukça nadirdir. Burada akut appendisit nedenli apendektomi yapılan hastada insidental olarak tanı alan pigmente nöroendokrin tümör olgusu literatür bilgileri eşliğinde sunulmuştur.

Anahtar Kelimeler

• apendiks,nöroendokrin,pigment,nöromelanin

Kaynakça

1. Alexandraki KI, Kaltsas GA, Grozinsky-Glasberg S, Chatzellis E, Grossman AB. Appendiceal neuroendocrine neoplasms: diagnosis and management. Endocrine-related cancer. 2016;23(1):R27-R41.
2. Iihara K, Yamaguchi K, Fujioka Y, Uno S. Pigmented neuroendocrine tumor of the lung, showing neuromelanin. Pathol Int. 2002;52(11):734-9.
3. Smith AE, Levi AW, Nadasdy T, Campbell KA, Fishman EK, Hruban RH. The pigmented "black" neuroendocrine tumor of the pancreas: a question of origin. Cancer. 2001;92(7):1984-91.
4. Chan ACL, Ho LC, Yip WWL, Cheung FC. Pigmented ependymoma with lipofuscin and neuromelanin production. Archives of pathology & laboratory medicine. 2003;127(7):872-5.
5. Bellezza G, Giansanti M, Cavaliere A, Sidoni A. Pigmented "black" pheochromocytoma of the adrenal gland: a case report and review of the literature. Archives of pathology & laboratory medicine. 2004;128(10):e125-e8.
6. Goel A, Addis B. Pigmented atypical carcinoid of the lung. Histopathology. 2007;51(2):263-5.
7. Kakkar A, Kaur K, Kumar T, Cherian LB, Kaushal R, Sharma MC, et al. Pigmented Pheochromocytoma: an Unusual Variant of a Common Tumor. Endocr Pathol. 2016;27(1):42-5.
8. Schneider U, Ihle V, Kohler B, Meier D, Frenzel H. Pigmented neuroendocrine carcinoma of the hepatic duct: a case report. Diagnostic Pathology. 2007;2(Suppl 1):S11.

9. Wahal SP, Mohindroo N, Mohindroo S. Black pancreatic neuro-endocrine tumor: A rare finding. Medical Journal of Dr DY Patil University. 2015;8(5):653.
10. Zhao L, Luo J, Zhang H, Da J. Pigmented paraganglioma of the kidney: a case report. Diagn Pathol. 2012;7:77.