Heterotopic pregnancy, which is rare after ovulation induction with clomiphene citrate and timed intercourse.

Yıl 2018, Cilt: 11 Sayı: 2, 169 - 172, 14.05.2018

Ümit Çabuş

https://doi.org/10.5505/ptd.2018.37929

Öz

The condition of the coexistence of intrauterine and extrauterine pregnancies is called as heterotopic pregnancy. The incidence is 1/30000 with natural conception and increases up to 1/100 with assisted reproductive techniques (ART). Clomiphene Citrate, a drug for ovulation induction, is used as a treatment approach for the patients with oligo-ovulation and subfertility with normal estrogen levels. This treatment may lead to the development of more than one follicle, ovarian hyperstimulation and multiple gestations. Increased estrogen level after ovulation induction disrupts tubal transport and increases ectopic pregnancy risk. In our case, we aimed to emphasize the difficulties of diagnosing heterotopic pregnancy, which is rare after ovulation induction with clomiphene citrate and timed intercourse, current diagnosis and treatment methods, as well as the importance of clinical and ultrasonographic evaluation of pelvic and adnexial structures of all terminated or ongoing first trimester pregnancies.

İngilizce Kısa Başlık: Clomiphene citrate induction and heterotopic pregnancy

Anahtar Kelimeler

Ovulation induction, Clomiphene Citrate, Heterotopic pregnancy

Klomifen sitrat ile ovulasyon indüksiyonu ve doğal ilişki sonrası ender görülen heterotopik gebelik

Öz

İntrauterin ve ekstrauterin gebeliğin aynı anda birlikte bulunmasına
heterotopik gebelik adı verilir. İnsidansı doğal ilişkiyle 1/30000 iken
yardımcı üreme teknikleri sonrasında 1/100 e kadar ulaşmaktadır. Ovulasyon
indüksiyonu yöntemlerinden Klomifen Sitrat normal östrojenize oligo-ovulasyonlu
ve subfertillerde seçilen bir tedavi yöntemidir. Bu tedavi birden fazla folikül
gelişmesine, ovaryan hiperstimülasyona ve çoğul gebeliğe neden olmaktadır.
Ovulasyon indüksiyonu sonrası artan östrojen seviyesi tubal transportu bozmakta
ve ektopik gebelik riskini arttırmaktadır. Biz olgumuzda klomifen sitrat
indüksiyonu ve doğal ilişki sonrası ender görülen heterotopik gebeliğin
teşhisinin zorluklarını, güncel tanı ve tedavi yöntemlerini, sonlanan veya
devam eden tüm ilk trimester gebeliklerde pelvik ve adneksiyel yapılarının
klinik ve ultrasonografik olarak değerlendirilmesinin önemini vurgulamayı
amaçladık.

Türkçe Kısa Başlık: Klomifen Sitrat indüksiyonu ve heterotopik gebelik

Anahtar Kelimeler

Ovulasyon indüksiyonu, Klomifen Sitrat, Heterotopik gebelik

Kaynakça

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