Yenidoğanda gelişen santral siyanozun nadir bir nedeni: Methemoglobinemi

Yıl 2018, Cilt: 11 Sayı: 2, 173 - 177, 14.05.2018

Tuba Leman Karakurt

https://doi.org/10.5505/ptd.2018.54771

Öz

Siyanoz; deri, tırnak yatağı veya mukozaların mavimsi gri görünümüdür ve
fizyolojik olmayan hemoglobin varlığı ya da deoksijenize hemoglobin düzeyinin
yüksekliği zemininde gözlenir.Yenidoğanda doğumu takiben ilk saatlerde ortaya
çıkan siyanozun nedeni genellikle kardiyak ya da pulmoner hastalıklardır. Ancak
ayırıcı tanıda daha nadir görülen nedenler de akılda tutulmalıdır.Bu tanılardan
biri methemoglobinemidir. Methemoglobinemi;ferröz demirin ferrik demire
oksitlenmesi sonucu oluşan ve dokulara yetersiz oksijen transferine neden olan,
siyanoz ile karakterize, ciddi bir hematolojik hastalıktır. Makalemizde hastanemizde
doğumdan sonra saatler içinde gelişen santral siyanoz nedeniyle yatırılan ve
edinsel methemoglobinemi tanısı alan iki olgu sunuldu. Maternal pudendal
anestezi nedeni ile gelişen edinsel methemoglobinemi vakaları intravenöz
metilen mavisi ile başarılı bir şekilde tedavi edilmiştir.

Türkçe Kısa Başlık: Yenidoğanda santral siyanozun nadir nedeni: Methemoglobinemi

Anahtar Kelimeler

Methemoglobinemi, yenidoğan, santral siyanoz

A rare cause of central cyanosis of newborn: Methemoglobinemia.

Öz

Cyanosis is blue-gray appearance of skin, nail bed or mucous membranes that occurs due to non-physiological disorders of hemoglobin or disorders involving deoxygenated hemoglobin. Cyanosis of newborn detected in the first hours of life following delivery is usually associated with pulmonary or cardiac diseases. However, other rare causes also has to be kept in mind in differential diagnosis. One of them is methemoglobinemia. Methemoglobinemia is a serious hemathologic disease results from oxidation of ferrous iron to ferric iron and causes inadequate oxygen transport to tissues and characterized with cyanosis. We report two cases who were hospitalized within the few hours after delivery due to cyanosis and diagnosed as acquired methemoglobinemia. Cases diagnosed as acquired methemoglobinemia caused by maternal pudendal anesthesia were treated successfully with intravenous methylen blue.

İngilizce Kısa Başlık: Central cyanosis of newborn: Methemoglobinemia

Anahtar Kelimeler

Methemoglobinemia, newborn, central cyanosis

Kaynakça

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