Yıl 2020, Cilt 13 , Sayı 3, Sayfalar 677 - 686 2020-09-18

Surgical treatment of intracranial epidermoid tumors: a retrospective analysis of 29 surgically treated patients
İntrakraniyal epidermoid tümörlerin cerrahi tedavisi: cerrahi olarak tedavi edilen 29 hastanın retrospektif analizi

Kadir OKTAY [1] , Ebru GUZEL [2] , Adnan DEMİRCİ [3] , Özlem Nuray SEVER [4] , Vildan KAYA [5] , Elif AKPINAR [6] , Mustafa YILDIRIM [7] , Aslan GÜZEL [8] , Hakan SEÇKİN [9]


Objective: Intracranial epidermoid tumors are benign, slow-growing, rare tumors. Although they are placed in different regions of the brain and cranium, they are predominantly located in the cerebellopontine angle and temporal region. In the present study, clinical findings and tumor location of epidermoid tumors, surgical methods and their results were examined. Materials and Methods: Medical records of 29 patients with intracranial epidermoid tumors diagnosed between 2012-2019 were retrospectively reviewed. Results: There were 16 female and 13 male patients in the study cohort. Tumors were located in cerebellopontine angle in 16 patients and other regions in 13 patients. Two of the 16 patients with tumors originating from cerebellopontine angle had both infra and supratentorial extension. One of these patients underwent subtotal resection in two sessions via retrosigmoid and subtemporal approaches. The tumor was excised except for the capsule adherent to eloquent vascular structures. The other patient underwent gross total resection with a single session via subtemporal approach. The other 14 cases were only infratentorial. In 25 patients gross total resection was performed and subtotal resection was performed in 4 patients. There were postoperative complications in 4 patients. One patient, whose tumor was adherent to the brainstem was lost in the postoperative period. There was no recurrence in any of the patients. Conclusion: The main purpose of treatment of intracranial epidermoid tumors should be gross total tumor resection by surgical intervention. However, subtotal resection may be performed by leaving a capsule adherent to eloquent neurovascular structures that may cause morbidity and mortality. The risk of recurrence of tumors in which total resection performed is very low.
Amaç: İntrakraniyal epidermoid tümörler iyi huylu, yavaş büyüyen ve nadir görülen tümörlerdir. Beynin ve kranyumun farklı bölgelerine görülebilmelerine rağmen, ağırlıklı olarak serebellopontin açı ve temporal bölgede yerleşirler. Bu çalışmada epidermoid tümörlerin klinik bulguları ve tümör yerleşimleri, cerrahi yöntemleri ve sonuçları incelendi. Materyal ve Metod: 2012-2019 yılları arasında tanı konulan intrakraniyal epidermoid tümörü bulunan 29 hastanın tıbbi kayıtları retrospektif olarak incelendi. Bulgular: Çalışma grubunda 16 kadın ve 13 erkek hasta vardı. Tümörler 16 hastada serebellopontin açıda ve 13 hastada diğer bölgelerde yerleşmişti. Serebellopontin açıdan köken alan tümörleri olan 16 hastanın ikisinde hem infra hem de supratentoryal uzanım mevcuttu. Bu hastalardan birine retrosigmoid ve subtemporal yaklaşımlarla iki seansta subtotal rezeksiyon uygulandı. Tümör, belirgin vasküler yapılara yapışan kapsülü dışında eksize edildi. Diğer hastaya ise subtemporal yaklaşımla tek seansla gros total rezeksiyon uygulandı. Diğer 14 olguda sadece infratentoryal yerleşim mevcuttu. 25 hastaya gros total rezeksiyon ve 4 hastaya subtotal rezeksiyon uygulandı. Dört hastada postoperatif komplikasyon gelişti. Tümörü beyin sapına yapışan bir hasta postoperatif dönemde kaybedildi. Hiçbir hastada nüks görülmedi. Sonuç: İntrakraniyal epidermoid tümörlerin tedavisinin temel amacı cerrahi müdahale ile gros total tümör rezeksiyonu olmalıdır. Bununla birlikte, subtotal rezeksiyon morbidite ve mortaliteye neden olabilecek durumlarda hayati nörovasküler yapılara yapışık kapsüller bırakılarak yapılabilir. Total rezeksiyon yapılan tümörlerin nüks riski çok düşüktür.
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Birincil Dil en
Konular Cerrahi
Yayınlanma Tarihi Eylül 2020
Bölüm Araştırma Makalesi
Yazarlar

Orcid: 0000-0003-2420-2734
Yazar: Kadir OKTAY (Sorumlu Yazar)
Kurum: Cukurova University Medicine School, Department of Neurosurgery
Ülke: Turkey


Orcid: 0000-0002-4523-8142
Yazar: Ebru GUZEL
Kurum: Gaziantep Medical Park Hospital, Department of Radiology
Ülke: Turkey


Orcid: 0000-0003-1256-3428
Yazar: Adnan DEMİRCİ
Kurum: Bursa Sevket Yilmaz Training and Research Hospital, Department of Neurosurgery
Ülke: Turkey


Orcid: 0000-0002-1436-5231
Yazar: Özlem Nuray SEVER
Kurum: Gaziantep University Medicine School, Department of Oncology
Ülke: Turkey


Orcid: 0000-0003-2763-5236
Yazar: Vildan KAYA
Kurum: Medstar Antalya Hospital, Department of Radiation Oncology
Ülke: Turkey


Orcid: 0000-0003-3724-6214
Yazar: Elif AKPINAR
Kurum: Medicana Konya Hospital, Department of Neurosurgery
Ülke: Turkey


Orcid: 0000-0002-1356-2451
Yazar: Mustafa YILDIRIM
Kurum: Bahcesehir University Medicine School, Department of Oncology
Ülke: Turkey


Orcid: 0000-0002-4235-6521
Yazar: Aslan GÜZEL
Kurum: Bahcesehir University Medicine School, Department of Neurosurgery
Ülke: Turkey


Orcid: 0000-0003-4724-6125
Yazar: Hakan SEÇKİN
Kurum: Medicana Bursa Hospital, Department of Neurosurgery
Ülke: Turkey


Tarihler

Yayımlanma Tarihi : 18 Eylül 2020

Bibtex @araştırma makalesi { patd670647, journal = {Pamukkale Tıp Dergisi}, issn = {}, eissn = {1308-0865}, address = {Pamukkale Üniversitesi Tıp Fakültesi Eğitim Blokları Kınıklı kampüsü 20070 Kınıklı, Denizli}, publisher = {Pamukkale Üniversitesi}, year = {2020}, volume = {13}, pages = {677 - 686}, doi = {10.31362/patd.670647}, title = {Surgical treatment of intracranial epidermoid tumors: a retrospective analysis of 29 surgically treated patients}, key = {cite}, author = {Oktay, Kadir and Guzel, Ebru and Demi̇rci̇, Adnan and Sever, Özlem Nuray and Kaya, Vildan and Akpınar, Elif and Yıldırım, Mustafa and Güzel, Aslan and Seçki̇n, Hakan} }
APA Oktay, K , Guzel, E , Demi̇rci̇, A , Sever, Ö , Kaya, V , Akpınar, E , Yıldırım, M , Güzel, A , Seçki̇n, H . (2020). Surgical treatment of intracranial epidermoid tumors: a retrospective analysis of 29 surgically treated patients . Pamukkale Tıp Dergisi , 13 (3) , 677-686 . DOI: 10.31362/patd.670647
MLA Oktay, K , Guzel, E , Demi̇rci̇, A , Sever, Ö , Kaya, V , Akpınar, E , Yıldırım, M , Güzel, A , Seçki̇n, H . "Surgical treatment of intracranial epidermoid tumors: a retrospective analysis of 29 surgically treated patients" . Pamukkale Tıp Dergisi 13 (2020 ): 677-686 <https://dergipark.org.tr/tr/pub/patd/issue/55097/670647>
Chicago Oktay, K , Guzel, E , Demi̇rci̇, A , Sever, Ö , Kaya, V , Akpınar, E , Yıldırım, M , Güzel, A , Seçki̇n, H . "Surgical treatment of intracranial epidermoid tumors: a retrospective analysis of 29 surgically treated patients". Pamukkale Tıp Dergisi 13 (2020 ): 677-686
RIS TY - JOUR T1 - Surgical treatment of intracranial epidermoid tumors: a retrospective analysis of 29 surgically treated patients AU - Kadir Oktay , Ebru Guzel , Adnan Demi̇rci̇ , Özlem Nuray Sever , Vildan Kaya , Elif Akpınar , Mustafa Yıldırım , Aslan Güzel , Hakan Seçki̇n Y1 - 2020 PY - 2020 N1 - doi: 10.31362/patd.670647 DO - 10.31362/patd.670647 T2 - Pamukkale Tıp Dergisi JF - Journal JO - JOR SP - 677 EP - 686 VL - 13 IS - 3 SN - -1308-0865 M3 - doi: 10.31362/patd.670647 UR - https://doi.org/10.31362/patd.670647 Y2 - 2020 ER -
EndNote %0 Pamukkale Tıp Dergisi Surgical treatment of intracranial epidermoid tumors: a retrospective analysis of 29 surgically treated patients %A Kadir Oktay , Ebru Guzel , Adnan Demi̇rci̇ , Özlem Nuray Sever , Vildan Kaya , Elif Akpınar , Mustafa Yıldırım , Aslan Güzel , Hakan Seçki̇n %T Surgical treatment of intracranial epidermoid tumors: a retrospective analysis of 29 surgically treated patients %D 2020 %J Pamukkale Tıp Dergisi %P -1308-0865 %V 13 %N 3 %R doi: 10.31362/patd.670647 %U 10.31362/patd.670647
ISNAD Oktay, Kadir , Guzel, Ebru , Demi̇rci̇, Adnan , Sever, Özlem Nuray , Kaya, Vildan , Akpınar, Elif , Yıldırım, Mustafa , Güzel, Aslan , Seçki̇n, Hakan . "Surgical treatment of intracranial epidermoid tumors: a retrospective analysis of 29 surgically treated patients". Pamukkale Tıp Dergisi 13 / 3 (Eylül 2020): 677-686 . https://doi.org/10.31362/patd.670647
AMA Oktay K , Guzel E , Demi̇rci̇ A , Sever Ö , Kaya V , Akpınar E , Yıldırım M , Güzel A , Seçki̇n H . Surgical treatment of intracranial epidermoid tumors: a retrospective analysis of 29 surgically treated patients. Pamukkale Tıp Dergisi. 2020; 13(3): 677-686.
Vancouver Oktay K , Guzel E , Demi̇rci̇ A , Sever Ö , Kaya V , Akpınar E , Yıldırım M , Güzel A , Seçki̇n H . Surgical treatment of intracranial epidermoid tumors: a retrospective analysis of 29 surgically treated patients. Pamukkale Tıp Dergisi. 2020; 13(3): 677-686.