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Examination of the effectiveness of 12-week Nordic Walking exercise in prediabetic individuals

Yıl 2022, Cilt 15, Sayı 2, 285 - 301, 01.04.2022
https://doi.org/10.31362/patd.1012513

Öz

Purpose: Nordic walking (NW) exercise is a type of exercise performed with batons, thus enabling the upper extremity to participate in the movement, reducing the load on the lower extremity and resulting in the involvement of large muscle groups. Exercise is recommended to prevent the development of diabetes mellitus. The aim of this study was to investigate the effects of NW exercise on insulin resistance, erythrocyte deformability, adipokine levels, oxidative stress in prediabetic women aged 40-65 years.
Materials and methods: Prediabetic individuals underwent progressive NW exercise at 65% of maximal heart rate for 3 days/week/12 weeks. Erythrocyte deformability was measured with an ektacytometer. Oxidative stress, serum adipokines were determined by commercial kits.
Results: NW exercise induced weight loss and decrement in body fat percentage (p<0.05). Waist, hips, thighs, chest circumferences were also reduced in response to exercise (p<0.05). NW exercise returned fasting blood glucose, insulin, HbA1c levels of prediabetic individuals to control levels (p=0.001, p=0.013 and p=0.021, respectively). Exercise yielded acute and prolonged increases in erythrocyte deformability of  prediabetic individuals (p<0.05). The first exercise session caused decrement of total oxidant status and oxidative stress (p=0.015 and p=0.013, respectively). No alteration in serum adipokines was detected.
Conclusions: Our results demonstrate that NW exercise may contribute to the  prevention of diabetes development in prediabetic individuals. It may also be beneficial in preventing the development of possible complications by regulating perfussion and acutely reducing oxidative stress.

Kaynakça

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Prediyabetik bireylerde 12 haftalık Nordic Walking egzersizinin etkinliğinin incelenmesi

Yıl 2022, Cilt 15, Sayı 2, 285 - 301, 01.04.2022
https://doi.org/10.31362/patd.1012513

Öz

Amaç: Nordic walking (NW) egzersizi batonlarla yapılan, dolayısıyla üst ekstremitenin de harekete katılımını sağlayarak alt ekstremiteye binen yükü azaltan, daha fazla kas grubunu çalıştıran popüler bir egzersiz türüdür. Diabetes mellitus gelişimini önlemek için egzersiz önerilir. Bu çalışmanın amacı 40-65 yaşlarındaki prediyabetik kadınlarda NW egzersizinin insülin direnci, eritrosit deformabilitesi, adipokin düzeyleri ve oksidatif stres üzerindeki etkilerini araştırmaktır.
Gereç ve yöntem: Prediyabetik bireylere (n=16) maksimum kalp hızının %65’inde, 3 gün/hafta, 12 haftalık ilerleyici NW egzersizi uygulanmıştır. Eritrosit deformabilitesi bir viskometre aracılığıyla ve oksidatif stres ile serum adipokin düzeyleri ticari kitlerle ölçülmüştür.

Bulgular: Uygulanan NW egzersizi hastaların kilo vermesine, vücut yağ yüzdelerinde azalmaya sebep olmuştur (p<0,05). Bel, kalça, uyluk, göğüs çevreleri de egzersiz sonucunda azalmıştır (p<0,05). Prediyabetik hastaların başlangıç açlık kan şekeri, serum insülin ve HbA1c düzeyleri sağlıklı gruptan yüksek iken (p=0,001, p=0,013 ve p=0,021, sırasıyla), uygulanan egzersiz programı bu parametrelerin kontrol  değerlerine dönmesine yol açmıştır. Egzersiz prediyabetik bireylerin eritrosit deformabilitesinde akut ve uzun süreli artışlara sebep olmuştur (p<0,05). Prediyabetik bireylerde ilk egzersiz seansı akut etkiyle total oksidan kapasite ve oksidatif

stres indeksinde azalma oluşturmuştur (p=0,015 ve p=0,013, sırasıyla). Serum adipokin düzeylerinde herhangi bir değişiklik saptanmamıştır.
Sonuç: Sonuçlarımız NW egzersiz eğitiminin prediyabetik bireylerde diyabet  gelişiminin önlenmesinde faydalı olabileceğini, doku kanlanmasını düzenlemek ve akut dönemde oksidatif stresi azaltmak suretiyle olası komplikasyonların gelişimine olumlu katkıları olabileceğini göstermektedir. 

Kaynakça

  • [1] Chakravarthy MV, Booth FW. Eating, exercise, and “thrifty” genotypes: connecting the dots toward an evolutionary understanding of modern chronic diseases. J Appl Physiol 2004;96(1):3–10. https://doi.org/10.1152/japplphysicol.00757.2003
  • [2] De Nardi AT, Tolves T, Lenzi TL, Signori LU, Silva AMVD. High-intensity interval training versus continuous training on physiological and metabolic variables in prediabetes and type 2 diabetes: a meta-analysis. Diabetes Res Clin Pract 2018;137:149-159. https://doi.org/10.1016/j.diabres.2017.12.017
  • [3] Bigagli E, Lodovici M. Circulating oxidative stress biomarkers in clinical studies on type 2 diabetes and ıts complications. Oxid Med Cell Longev 2019;2019:5953685. https://doi.org/10.1155/2019/5953685.
  • [4] Earnest CP. Exercise interval training: an improved stimulus for improving the physiology of pre-diabetes. Med Hypotheses 2008;71(5):752-761. https://doi.org/10.1016/j.mehy.2008.06.024
  • [5] Tabák AG, Herder C, Rathmann W, Brunner EJ, Kivimäki M. Prediabetes: a high-risk state for diabetes development. Lancet 2012;379(9833):2279-2290. https://doi.org/10.1016/S0140-6736(12)60283-9
  • [6] Aydin S. Three new players in energy regulation: preptin, adropin and irisin. Peptides 2014;56:94-110. https://doi.org/10.1016/j.peptides.2014.03.021
  • [7] Perakakis N, Triantafyllou GA, Fernández-Real JM. et al. Physiology and role of irisin in glucose homeostasis. Nat Rev Endocrinol 2017;13(6):324-337. https://doi.org/10.1038/nrendo.2016.221
  • [8] Buchanan CM, Phillips AR, Cooper GJ. Preptin derived from proinsulin-like growth factor II (proIGF-II) is secreted from pancreatic islet beta-cells and enhances insülin secretion. Biochem J 2001;360(2):431–439. https://doi.org/10.1042/0264-6021:3600431
  • [9] Cheng KC, Li YX, Asakawa A. et al. Characterization of preptin-induced insulin secretion in pancreaticcells. J Endocrinol 2012;215(1):43-49. https://doi.org/10.1530/JOE-12-0176
  • [10] Yang G, Li L, Chen W, Liu H, Boden G, Li K. Circulating preptin levels in normal, impaired glucose tolerance, and type 2 diabetic subjects. Ann Med 2009;41(1):52-56. https://doi.org/10.1080/07853890802244142
  • [11] Filková M, Haluzík M, Gay S, Senolt L. The role of resistin as a regülatör of inflammation: Implications for various human pathologies. Clin Immunol 2009;133(2):157-170. https://doi.org/10.1016/j.clim.2009.07.013
  • [12] Vozarova de Courten B, Degawa-Yamauchi M, Considine RV, Tataranni PA. High serum resistin is associated with an increase in adiposity but not a worsening of insulin resistance in pima indians. Diabetes 2004;53(5):1279-1284. https://doi.org/10.2337/diabetes.53.5.1279
  • [13] Mawatari S, Saito K, Murakami K, Fujino T. Absence of correlation between glycated hemoglobin and lipid composition of erythrocyte membrane in type 2 diabetic patients. Metabolism 2004;53(1):123-127. https://doi.org/10.1016/j.metabol.2003.07.016
  • [14] Keymel S, Heiss C, Kleinbongard P, Kelm M, Lauer T. Impaired red blood cell deformability in patients with coronary artery disease and diabetes mellitus. Horm Metab Res 2011;43(11):760-765. https://doi.org/10.1055/s-0031-1286325
  • [15] Schwartz RS, Madsen JW, Rybicki AC, Nagel RL. Oxidation of spectrin and deformability defects in diabetic erythrocytes. Diabetes 1991;40(6):701-708. https://doi.org/10.2337/diab.40.6.701
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Ayrıntılar

Birincil Dil İngilizce
Konular Fizyoloji
Yayınlanma Tarihi Nisan 2022
Bölüm Araştırma Makalesi
Yazarlar

Mustafa ÖZDAMAR
Karamanoğlu mehmetbey üniversitesi
0000-0003-0077-7234
Türkiye


Özgen KILIÇ ERKEK
Pamukkale Üniversitesi
0000-0001-8037-099X
Türkiye


Süleyman TÜMKAYA
0000-0002-9366-0205
Türkiye


Hatice Çağla ÖZDAMAR
Karamanoğlu mehmetbey üniversitesi
0000-0003-3868-4797
Türkiye


Ali ÖZDAMAR
0000-0002-6104-8185
Türkiye


Hilmiye PAKYÜREK
PAMUKKALE ÜNİVERSİTESİ, TIP FAKÜLTESİ
0000-0002-7084-3770
Türkiye


Melek TUNÇ-ATA
PAMUKKALE ÜNİVERSİTESİ, TIP FAKÜLTESİ
0000-0002-0384-2356
Türkiye


Hande ŞENOL
PAMUKKALE ÜNİVERSİTESİ
0000-0001-6395-7924
Türkiye


Emine KILIÇ TOPRAK
PAMUKKALE ÜNİVERSİTESİ, TIP FAKÜLTESİ
0000-0002-8795-0185
Türkiye


Z. Melek BOR KÜÇÜKATAY (Sorumlu Yazar)
PAU. Tıp Fakültesi Fizyoloji
0000-0002-9366-0205
Türkiye

Destekleyen Kurum PAU Bilimsel Araştırma Projeleri Koordinasyon Birimi
Proje Numarası 2019SABE006
Yayımlanma Tarihi 1 Nisan 2022
Kabul Tarihi 1 Şubat 2022
Yayınlandığı Sayı Yıl 2022, Cilt 15, Sayı 2

Kaynak Göster

Bibtex @araştırma makalesi { patd1012513, journal = {Pamukkale Tıp Dergisi}, eissn = {1308-0865}, address = {Pamukkale Üniversitesi Tıp Fakültesi Eğitim Blokları Kınıklı kampüsü 20070 Kınıklı, Denizli}, publisher = {Pamukkale Üniversitesi}, year = {2022}, volume = {15}, number = {2}, pages = {285 - 301}, doi = {10.31362/patd.1012513}, title = {Examination of the effectiveness of 12-week Nordic Walking exercise in prediabetic individuals}, key = {cite}, author = {Özdamar, Mustafa and Kılıç Erkek, Özgen and Tümkaya, Süleyman and Özdamar, Hatice Çağla and Özdamar, Ali and Pakyürek, Hilmiye and Tunç-ata, Melek and Şenol, Hande and Kılıç Toprak, Emine and Bor Küçükatay, Z. Melek} }
APA Özdamar, M. , Kılıç Erkek, Ö. , Tümkaya, S. , Özdamar, H. Ç. , Özdamar, A. , Pakyürek, H. , Tunç-ata, M. , Şenol, H. , Kılıç Toprak, E. & Bor Küçükatay, Z. M. (2022). Examination of the effectiveness of 12-week Nordic Walking exercise in prediabetic individuals . Pamukkale Tıp Dergisi , 15 (2) , 285-301 . DOI: 10.31362/patd.1012513
MLA Özdamar, M. , Kılıç Erkek, Ö. , Tümkaya, S. , Özdamar, H. Ç. , Özdamar, A. , Pakyürek, H. , Tunç-ata, M. , Şenol, H. , Kılıç Toprak, E. , Bor Küçükatay, Z. M. "Examination of the effectiveness of 12-week Nordic Walking exercise in prediabetic individuals" . Pamukkale Tıp Dergisi 15 (2022 ): 285-301 <https://dergipark.org.tr/tr/pub/patd/issue/65532/1012513>
Chicago Özdamar, M. , Kılıç Erkek, Ö. , Tümkaya, S. , Özdamar, H. Ç. , Özdamar, A. , Pakyürek, H. , Tunç-ata, M. , Şenol, H. , Kılıç Toprak, E. , Bor Küçükatay, Z. M. "Examination of the effectiveness of 12-week Nordic Walking exercise in prediabetic individuals". Pamukkale Tıp Dergisi 15 (2022 ): 285-301
RIS TY - JOUR T1 - Examination of the effectiveness of 12-week Nordic Walking exercise in prediabetic individuals AU - Mustafa Özdamar , Özgen Kılıç Erkek , Süleyman Tümkaya , Hatice Çağla Özdamar , Ali Özdamar , Hilmiye Pakyürek , Melek Tunç-ata , Hande Şenol , Emine Kılıç Toprak , Z. Melek Bor Küçükatay Y1 - 2022 PY - 2022 N1 - doi: 10.31362/patd.1012513 DO - 10.31362/patd.1012513 T2 - Pamukkale Tıp Dergisi JF - Journal JO - JOR SP - 285 EP - 301 VL - 15 IS - 2 SN - -1308-0865 M3 - doi: 10.31362/patd.1012513 UR - https://doi.org/10.31362/patd.1012513 Y2 - 2022 ER -
EndNote %0 Pamukkale Tıp Dergisi Examination of the effectiveness of 12-week Nordic Walking exercise in prediabetic individuals %A Mustafa Özdamar , Özgen Kılıç Erkek , Süleyman Tümkaya , Hatice Çağla Özdamar , Ali Özdamar , Hilmiye Pakyürek , Melek Tunç-ata , Hande Şenol , Emine Kılıç Toprak , Z. Melek Bor Küçükatay %T Examination of the effectiveness of 12-week Nordic Walking exercise in prediabetic individuals %D 2022 %J Pamukkale Tıp Dergisi %P -1308-0865 %V 15 %N 2 %R doi: 10.31362/patd.1012513 %U 10.31362/patd.1012513
ISNAD Özdamar, Mustafa , Kılıç Erkek, Özgen , Tümkaya, Süleyman , Özdamar, Hatice Çağla , Özdamar, Ali , Pakyürek, Hilmiye , Tunç-ata, Melek , Şenol, Hande , Kılıç Toprak, Emine , Bor Küçükatay, Z. Melek . "Examination of the effectiveness of 12-week Nordic Walking exercise in prediabetic individuals". Pamukkale Tıp Dergisi 15 / 2 (Nisan 2022): 285-301 . https://doi.org/10.31362/patd.1012513
AMA Özdamar M. , Kılıç Erkek Ö. , Tümkaya S. , Özdamar H. Ç. , Özdamar A. , Pakyürek H. , Tunç-ata M. , Şenol H. , Kılıç Toprak E. , Bor Küçükatay Z. M. Examination of the effectiveness of 12-week Nordic Walking exercise in prediabetic individuals. Pam Tıp Derg. 2022; 15(2): 285-301.
Vancouver Özdamar M. , Kılıç Erkek Ö. , Tümkaya S. , Özdamar H. Ç. , Özdamar A. , Pakyürek H. , Tunç-ata M. , Şenol H. , Kılıç Toprak E. , Bor Küçükatay Z. M. Examination of the effectiveness of 12-week Nordic Walking exercise in prediabetic individuals. Pamukkale Tıp Dergisi. 2022; 15(2): 285-301.
IEEE M. Özdamar , Ö. Kılıç Erkek , S. Tümkaya , H. Ç. Özdamar , A. Özdamar , H. Pakyürek , M. Tunç-ata , H. Şenol , E. Kılıç Toprak ve Z. M. Bor Küçükatay , "Examination of the effectiveness of 12-week Nordic Walking exercise in prediabetic individuals", Pamukkale Tıp Dergisi, c. 15, sayı. 2, ss. 285-301, Nis. 2022, doi:10.31362/patd.1012513
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