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Phytochemical Research and Evaluation of Tarragon (Artemisia dracunculus L.) as a Food Additive

Yıl 2022, Cilt: 3 Sayı: 2, 50 - 60, 30.12.2022
https://doi.org/10.53501/rteufemud.1160846

Öz

In this study, tarragon (Artemisia dracunculus L.) the amount of antioxidants and phenolic substances of water-based extracts in various concentrations (25g/L, 50g/L, 100g/L) with the aroma components of the plant was determined. Various food pathogens (Escherichia coli ATCC 25922, Salmonella enterica ATCC 13076, Listeria monocytogenes ATCC 43251) and bacterial strains ((Gram-negative (Vibrio harveyi (KF443058), Vibrio vulnificus (KF443056), Aeromonas veronii (KF443053), Vibrio anguillarum (NR 029254.1) and Vibrio campbellii (MH231447.1), Vibrio rotiferianus (NR 042081.1), Vibrio ponticus (NR 029032.1), Psychrobacter marincola (NR 025458.1), Pseudoalteromonas prydzensis (NR 044803.1), Pseudoalteromonas mariniglutinosa (NR 028992.1) and Gram-positive (Bacillus thuringiensis (NR 043403.1)) obtained from naturally infected Dicentrarchus labrax fish were determined by the disk diffusion method on their antimicrobial properties. As a result of the study, antioxidant values were found to be 88.5% at maximum concentrations of 10%, while the total phenolic substance content was determined between 3.75-5.06 mg GAE/g values. The main component of the tarragon plant was terpinyl acetate (23.16%), followed by α-terpineol (20.08%), anethole-(Z) (8.93%), limonene (5.20%), spathulenol (4.47%), ısoeugenol (3.73%), valeric acid (3.40%), eucalyptol (3.26%). No antimicrobial activity was determined on the test microorganisms used in the study.

Kaynakça

  • Aliferis K.A., Tarantilis P.A., Harizanis P.C., Alissandrakis E. (2010). Botanical discrimination and classification of honey samples applying gas chromatography/mass spectrometry fingerprinting of headspace volatile compounds. Food Chemistry, 121 (3), pp. 856-862, 10.1016/j.foodchem.2009.12.098
  • Aprotosoaie, A.C., Costache, I.I., Miron, A. (2016). Anethole and its role in chronic diseases. Adv. Exp. Med. Biol., 929, 247–267. Atoui, A. K., Mansouri, A., Boskou, G., Kefalas, P. (2005). Tea and herbal infusions: their antioxidant activity and phenolic profile.Food chemistry,89(1), 27-36.
  • Attokaran, M. (2011). Essential oils. Natural food flavors and colorants, 13-15.
  • Bahmani, L., Aboonajmi, M., Arabhosseini, A., Mirsaeedghazi, H. (2018). Effects of ultrasound pre-treatment on quantity and quality of essential oil of tarragon (Artemisia dracunculus L.) leaves.Journal of Applied Research on Medicinal and Aromatic Plants,8, 47-52.
  • Bahramikia S., Yazdanparast R., Nosrati N. A., (2008). Comparision of antioxidant capacities of ethanol extracts of Satureja hortensis and Artemisia dracunculus leaves. Pharmacolonline, 2: 694 - 704.
  • Bauer, A. W., Roberts, C. E., Kirby, W. M. (1960). Single disc versus multiple disc and plate dilution techniques for antibiotic sensitivity testing. Antibiot. Annu. 7, 574- 580.
  • Bayramoğlu, M. (2009). The antioxidant properties of volatile oils obtained from the Artemisia taurica Willd. and Salvia kronenburgii Rech.Fil. plants and their effects on xanthine oxidase. Master’s Thesis. Yüzüncü Yıl University, Graduate School of Natural and Applied Sciences, Department of Chemistry, Türkiye.
  • Becker, E. M., Nissen, L. R., Skibsted, L. H. (2004). Antioxidant evaluation protocols: Food quality or health effects.European Food Research and Technology,219(6), 561-571.
  • Benli, M., Kaya, I., Yigit, N. (2007). Screening antimicrobial activity of various extracts of Artemisia dracunculus L.Cell Biochemistry and Function: Cellular biochemistry and its modulation by active agents or disease,25(6), 681-686.
  • Berger M.M. (2005). Can oxidative damage be treated nutritionally Clinical Nutrition, 24:172-183.
  • Bicas, J. L., Fontanille, P., Pastore, G. M., Larroche, C. (2010). A bioprocess for the production of high concentrations of R-(+)-alpha-terpineol from R-(+)-limonene.Process Biochemistry, 45(4), 481–486.https://doi.org/10.1016/j.procbio.2009.11.007.
  • Brand-Williams, W.M.E., Berset, C. (1995). Use of afree radical method to evaluate antioxidant activity. LWT-Food Science and Technology, 28(1), 25-30. Chaleshtori, R. S., Rokni, N., Razavilar, V., Kopaei, M. R. (2013). The evaluation of the antibacterial and antioxidant activity of Tarragon (Artemisia dracunculus L.) essential oil and its chemical composition.Jundishapur Journal of Microbiology,6(9).
  • Chemat S., Tomao V., Chemat F. (2012). Limonene as Green solvent for extraction of natural productS,Green Solvents I: Properties and Applications in Chemistry, Springer Netherlands,Amsterdam, pp.175-186
  • Çelebi, M., Ağirtaş, M. S., Dundar, A. (2015). Different peripheral substituted phthalocyanines: Synthesis, characterization, aggregation behavior, antioxidant and antibacterial activity.Journal of Structural Chemistry,56(8), 1638-1645.
  • Dülger, B., Ceylan, M., Alitsaous, M., Uğurlu, E. (1999). Artemisia absinthium L. (Pelin)’un antimikrobiyal aktivitesi. Turkish Journal of Biology, 23(3), 377-384.
  • Fildan, A. P., Pet, I., Stoin, D., Bujanca, G., Lukinich-Gruia, A. T., Jianu, C., Tofolean, D. E. (2019). Artemisia dracunculus essential oil chemical composition and antioxidant properties.Revista de Chimie,70(1), 59-62.
  • Filipsson A.F., Bard J., Karlsson S.(1998). Limonene (fifth ed.),World Health Organization (1998), p.32
  • Gargacı, A. (2010). The effect of rosemary (Rosmarinus officinalis L.) extract on the shelf life of anchovy (Engraulis encrasicholus, L., 1758) stored in the refrigerator, Master's Thesis, Sinop University Institute of Science and Technology, Türkiye.
  • Gawlik-Dziki, U. (2012). Dietary spices as a natural effectors of lipoxygenase, xanthine oxidase, peroxidase and antioxidant agents. LWT- Food Sci. Technol. 47: 138 - 46. Gürdal, A. A. (2021). Evaluation of Diospyros kaki (persimmon), Prunus lauroceraus (cherry laurel) and Vaccinium arctostaphylos (blue berry) Fruits as a Natural Antioxidant Source.
  • Hamurcu, T. (2016). Investigation of the Bayburt region tarragon (Artemisia dracunculus) plant dried by different methods in terms of its functional properties and its effect on vegetable oil stability, Master's thesis, Institute of Science and Technology, Türkiye
  • Hirota R., Roger N.N., Nakamura H., Song H.S., Sawamura M, Suganuma N. (2010). Anti-inflammatory effects of limonene from (citrus junos Tanaka) essential oil on eosinophils. J. Food Sci.,75.
  • Karabulut, H., Gülay, M. Ş. (2016). Free radicals. Mehmet Akif Ersoy University. Health Journal of the Faculty of Sciences, 4(1), 50-59.
  • Karslı, B. (2020). Antibacterial and antioxidant activity of pulp, peel and leaves of Feijoa sellowiana: Effect of extraction techniques, solvents and concentration. Food and Health,(1), 21-30.
  • Kenar, M. (2009). Effect of natural antioxidants obtained from aromatic plants on fish fillet examination of sensory, chemical and microbiological effects, Master's Thesis, Cukurova University Graduate School of Natural and Applied Sciences, Türkiye.
  • Kobya, O., Kara B., Yaylaci, A.B., Çağlak, E. (2021). Antioxidant potential of chestnut bark, nettle, kiwi and citrus extracts and antimicrobial effects against some fish pathogens. Anatolian Journal of Environmental and Animal Sciences, 6(2), 204-210.
  • Kordali, S., Kotan, R., Mavi, A., Cakır, A., Ala, A., Yıldırım, A. (2005). Determination of the chemical composition and antioxidant activity of the essential oil of Artemisia dracunculus and of the antifungal and antibacterial activities of Turkish Artemisia absinthium, A. dracunculus, Artemisia santonicum, and Artemisia spicigera essential oils. Journal of agricultural and food chemistry,53(24), 9452-9458.
  • Küçükgülmez, A., Çelik, M., Kadak, A. E., Çıkrıkçı, M. (2011). Proximate and fatty acid composition of the keeled mullet (Liza carinata) from the North East Mediterranean Sea. Journal of Applied Biological Sciences, 5(1), 17-19
  • Kirk-Ballard, H., Kilroy, G., Day, B.C., Wang, Z.Q., Ribnicky, D.M., Cefalu, W.T., Floyd, Z.E. (2014). An ethanolic extract of Artemisia dracunculus L. regulates gene expression of ubiquitin–proteasome system enzymes in skeletal muscle: Potential role in the treatment of sarcopenic obesity. Nutrition 30, 21-25.
  • Molina, G., Pessôa, M.G., Bicas, J.L., Fontanille, P., Larroche, C., Pastore, G.M. (2019). Optimization of limonene biotransformation for the production of bulk amounts of α-terpineol.Bioresource Technology. https://doi.org/10.1016/j.biortech.2019.122180
  • Nurzyńska-Wierdak, R., Grażyna, Z.(2014).Plant yield and bioactive compounds of tarragon (Artemisia dracunculus L.) affected by plant density.Acta Scientiarum Polonorum Hortorum Cultus,13(2),207–221
  • Obolskiy, D., Pischel, I., Feistel, B., Glotov, N., Heinrich, M. (2011). Artemisia dracunculus L.(tarragon): a critical review of its traditional use, chemical composition, pharmacology, and safety. Journal of Agricultural and Food Chemistry, 59(21), 11367-11384.
  • Öğretmen, Ö. Y. (2022). Determination of antioxidant activity of plant parts of Scilla bifolia L. (Forest hyacinth). Anatolian Journal of Environment and Animals, 7(1), 9-14. https://doi.org/10.35229/jaes.980980
  • Roberto D., Micucci P., Sebastian T., Graciela F., Anesini C. (2010). Antioxidant activity of limonene on normal murine lymphocytes: relation to H2O2 modulation and cell proliferation. Basic Clin. Pharmacol. Toxicol.,106(2010), pp.38 Sayyah, M., Nadjafnia, L., Kamalinejad, M. (2004). Anticonvulsant activity and chemical composition of Artemisia dracunculus L. essential oil.Journal of ethnopharmacology,94(2-3), 283-287
  • Sokal, R.R., Rohlf, F.J. (1987). Biostatistics.Francise Co, New York.
  • Singleton, V.L., Rossi, J.A. (1965). Colorimetry of Total Phenolics with Phosphomolybdic Phosphotungstic Acid Reagents, 16, 144-158.
  • Singh, H. P., Kaur, S., Mittal, S., Batish, D. R., Kohli, R. K. (2009). Essential oil of Artemisia scoparia inhibits plant growth by generating reactive oxygen species and causing oxidative damage.Journal of chemical ecology,35(2), 154-162.
  • Sun J.(2007). D-Limonene: safety and clinical applications. Alternative Med. Rev.,12(3), 259-264.
  • Suja, K. P., Jayalekshmy, A., Arumughan, C. (2005). Antioxidant activity of sesame cake extract.Food chemistry,91(2), 213-219.
  • URL–1,(2022).https://www.hurriyet.com.tr/mahmure/gallery-tarragon-whatis-how-used-ask-tarragon-herb-benefits-41960588, 2 July 2022.
  • Uzun, E. (2013). Bacterial Pathogens Causing Mortalities in The Sea Bass (Dicentrarchus labrax) and Determination of Seasonal Occurrence in The Eastern Black Sea. Master thesis, Karadeniz Technical University, The Graduate School of Natural and Applied Sciences, Trabzon, Turkey.
  • Uzun, E. Ogut, H., (2015). The isolation frequency of bacterial pathogens from sea bass (Dicentrarchus labrax) in the Southeastern Black Sea. Aquaculture, 437,30-37.
  • Valko, M., Rhodes, C. J. B., Moncol, J., Izakovic, M. M., Mazur, M. (2006). Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chemico-biological interactions,160(1), 1-40.
  • Vandanmagsar, B., Haynie, K., Wicks, S., Bermudez, E., Mendoza, T., Ribnicky, D., Cefalu, W. Mynatt, R. (2014). Artemisia dracunculus L. L. extract ameliorates insulin sensitivity by attenuating inflammatory signalling in human skeletal muscle culture. Diabetes, Obesity and Metabolism, 16, 728-738.
  • Yaichibe, T., Masanori, K., Kenichi, A. (1997). Morphological characters and essential oil in Artemisia dracunculus (French Tarragon) and Artemisia dracuncloides (Russian Tarragon).Tokyo Nogyo Daigaku Nogaku Shuho,41(4), 229-238.
  • Yaylacı E.U., (2019). Developing a differentiation technique for the pathogenic bacteria causing disease in sea bass (Dicentrarchus labrax) by using artifıcial neural networks. Doctoral Thesis, Karadeniz Technical University, The Graduate School of Natural and Applied Sciences, Trabzon, Turkey, 49–50.

Tarhun (Artemisia dracunculus L.)'un Fitokimyasal Araştırması ve Gıda Katkı Maddesi Olarak Değerlendirilmesi

Yıl 2022, Cilt: 3 Sayı: 2, 50 - 60, 30.12.2022
https://doi.org/10.53501/rteufemud.1160846

Öz

Bu çalışmada, tarhun (Artemisia dracunculus L.) bitkisinin aroma bileşenleri ile çeşitli konsantrasyonlarda (25g/L, 50g/L, 100g/L) su bazlı ekstraktlarının antioksidan ve fenolik madde miktarı tespit edilmiştir. Çeşitli gıda patojenleri (Escherichia coli ATCC 25922, Salmonella enterica ATCC 13076, Listeria monocytogenes ATCC 43251, Staphylococcus aureus ATCC 2592) ve doğal olarak enfekte olmuş Dicentrarchus labrax balıklarından elde edilen Gram-negatif (Vibrio harveyi (KF443058), Vibrio vulnificus (KF443056), Aeromonas veronii (KF443053), Vibrio anguillarum (NR 029254.1) ve Vibrio campbellii (MH231447.1), Vibrio rotiferianus (NR 042081.1), Vibrio ponticus (NR 029032.1), Psychrobacter marincola (NR 025458.1), Pseudoalteromonas prydzensis (NR 044803.1), Pseudoalteromonas mariniglutinosa (NR 028992.1) ve Gram-pozitif (Bacillus thuringiensis (NR 043403.1) suşları üzerinde antimikrobiyal özellikleri disk difüzyon yöntemi ile belirlenmiştir. Çalışma sonucunda antioksidan değerleri maksimum %88,5 bulunurken, toplam fenolik madde içeriği 3,75- 5,06 mg GAE/g değerleri arasında tespit edilmiştir. Tarhun bitkisinin esas bileşeninin Terpinyl acetate (% 23,16) olduğu, bunu α-Terpineol (%20,08), Anethole-(Z) (%8,93), Limonene (%5,20), Spathulenol (%4,47), Isoeugenol (%3,73), Valeric acid (%3,40), Eucalyptol’un (%3,26) takip ettiği gözlenmiştir. Çalışmada kullanılan test mikroorganizmaları üzerinde herhangi bir antimikrobiyal aktivite belirlenmemiştir.

Kaynakça

  • Aliferis K.A., Tarantilis P.A., Harizanis P.C., Alissandrakis E. (2010). Botanical discrimination and classification of honey samples applying gas chromatography/mass spectrometry fingerprinting of headspace volatile compounds. Food Chemistry, 121 (3), pp. 856-862, 10.1016/j.foodchem.2009.12.098
  • Aprotosoaie, A.C., Costache, I.I., Miron, A. (2016). Anethole and its role in chronic diseases. Adv. Exp. Med. Biol., 929, 247–267. Atoui, A. K., Mansouri, A., Boskou, G., Kefalas, P. (2005). Tea and herbal infusions: their antioxidant activity and phenolic profile.Food chemistry,89(1), 27-36.
  • Attokaran, M. (2011). Essential oils. Natural food flavors and colorants, 13-15.
  • Bahmani, L., Aboonajmi, M., Arabhosseini, A., Mirsaeedghazi, H. (2018). Effects of ultrasound pre-treatment on quantity and quality of essential oil of tarragon (Artemisia dracunculus L.) leaves.Journal of Applied Research on Medicinal and Aromatic Plants,8, 47-52.
  • Bahramikia S., Yazdanparast R., Nosrati N. A., (2008). Comparision of antioxidant capacities of ethanol extracts of Satureja hortensis and Artemisia dracunculus leaves. Pharmacolonline, 2: 694 - 704.
  • Bauer, A. W., Roberts, C. E., Kirby, W. M. (1960). Single disc versus multiple disc and plate dilution techniques for antibiotic sensitivity testing. Antibiot. Annu. 7, 574- 580.
  • Bayramoğlu, M. (2009). The antioxidant properties of volatile oils obtained from the Artemisia taurica Willd. and Salvia kronenburgii Rech.Fil. plants and their effects on xanthine oxidase. Master’s Thesis. Yüzüncü Yıl University, Graduate School of Natural and Applied Sciences, Department of Chemistry, Türkiye.
  • Becker, E. M., Nissen, L. R., Skibsted, L. H. (2004). Antioxidant evaluation protocols: Food quality or health effects.European Food Research and Technology,219(6), 561-571.
  • Benli, M., Kaya, I., Yigit, N. (2007). Screening antimicrobial activity of various extracts of Artemisia dracunculus L.Cell Biochemistry and Function: Cellular biochemistry and its modulation by active agents or disease,25(6), 681-686.
  • Berger M.M. (2005). Can oxidative damage be treated nutritionally Clinical Nutrition, 24:172-183.
  • Bicas, J. L., Fontanille, P., Pastore, G. M., Larroche, C. (2010). A bioprocess for the production of high concentrations of R-(+)-alpha-terpineol from R-(+)-limonene.Process Biochemistry, 45(4), 481–486.https://doi.org/10.1016/j.procbio.2009.11.007.
  • Brand-Williams, W.M.E., Berset, C. (1995). Use of afree radical method to evaluate antioxidant activity. LWT-Food Science and Technology, 28(1), 25-30. Chaleshtori, R. S., Rokni, N., Razavilar, V., Kopaei, M. R. (2013). The evaluation of the antibacterial and antioxidant activity of Tarragon (Artemisia dracunculus L.) essential oil and its chemical composition.Jundishapur Journal of Microbiology,6(9).
  • Chemat S., Tomao V., Chemat F. (2012). Limonene as Green solvent for extraction of natural productS,Green Solvents I: Properties and Applications in Chemistry, Springer Netherlands,Amsterdam, pp.175-186
  • Çelebi, M., Ağirtaş, M. S., Dundar, A. (2015). Different peripheral substituted phthalocyanines: Synthesis, characterization, aggregation behavior, antioxidant and antibacterial activity.Journal of Structural Chemistry,56(8), 1638-1645.
  • Dülger, B., Ceylan, M., Alitsaous, M., Uğurlu, E. (1999). Artemisia absinthium L. (Pelin)’un antimikrobiyal aktivitesi. Turkish Journal of Biology, 23(3), 377-384.
  • Fildan, A. P., Pet, I., Stoin, D., Bujanca, G., Lukinich-Gruia, A. T., Jianu, C., Tofolean, D. E. (2019). Artemisia dracunculus essential oil chemical composition and antioxidant properties.Revista de Chimie,70(1), 59-62.
  • Filipsson A.F., Bard J., Karlsson S.(1998). Limonene (fifth ed.),World Health Organization (1998), p.32
  • Gargacı, A. (2010). The effect of rosemary (Rosmarinus officinalis L.) extract on the shelf life of anchovy (Engraulis encrasicholus, L., 1758) stored in the refrigerator, Master's Thesis, Sinop University Institute of Science and Technology, Türkiye.
  • Gawlik-Dziki, U. (2012). Dietary spices as a natural effectors of lipoxygenase, xanthine oxidase, peroxidase and antioxidant agents. LWT- Food Sci. Technol. 47: 138 - 46. Gürdal, A. A. (2021). Evaluation of Diospyros kaki (persimmon), Prunus lauroceraus (cherry laurel) and Vaccinium arctostaphylos (blue berry) Fruits as a Natural Antioxidant Source.
  • Hamurcu, T. (2016). Investigation of the Bayburt region tarragon (Artemisia dracunculus) plant dried by different methods in terms of its functional properties and its effect on vegetable oil stability, Master's thesis, Institute of Science and Technology, Türkiye
  • Hirota R., Roger N.N., Nakamura H., Song H.S., Sawamura M, Suganuma N. (2010). Anti-inflammatory effects of limonene from (citrus junos Tanaka) essential oil on eosinophils. J. Food Sci.,75.
  • Karabulut, H., Gülay, M. Ş. (2016). Free radicals. Mehmet Akif Ersoy University. Health Journal of the Faculty of Sciences, 4(1), 50-59.
  • Karslı, B. (2020). Antibacterial and antioxidant activity of pulp, peel and leaves of Feijoa sellowiana: Effect of extraction techniques, solvents and concentration. Food and Health,(1), 21-30.
  • Kenar, M. (2009). Effect of natural antioxidants obtained from aromatic plants on fish fillet examination of sensory, chemical and microbiological effects, Master's Thesis, Cukurova University Graduate School of Natural and Applied Sciences, Türkiye.
  • Kobya, O., Kara B., Yaylaci, A.B., Çağlak, E. (2021). Antioxidant potential of chestnut bark, nettle, kiwi and citrus extracts and antimicrobial effects against some fish pathogens. Anatolian Journal of Environmental and Animal Sciences, 6(2), 204-210.
  • Kordali, S., Kotan, R., Mavi, A., Cakır, A., Ala, A., Yıldırım, A. (2005). Determination of the chemical composition and antioxidant activity of the essential oil of Artemisia dracunculus and of the antifungal and antibacterial activities of Turkish Artemisia absinthium, A. dracunculus, Artemisia santonicum, and Artemisia spicigera essential oils. Journal of agricultural and food chemistry,53(24), 9452-9458.
  • Küçükgülmez, A., Çelik, M., Kadak, A. E., Çıkrıkçı, M. (2011). Proximate and fatty acid composition of the keeled mullet (Liza carinata) from the North East Mediterranean Sea. Journal of Applied Biological Sciences, 5(1), 17-19
  • Kirk-Ballard, H., Kilroy, G., Day, B.C., Wang, Z.Q., Ribnicky, D.M., Cefalu, W.T., Floyd, Z.E. (2014). An ethanolic extract of Artemisia dracunculus L. regulates gene expression of ubiquitin–proteasome system enzymes in skeletal muscle: Potential role in the treatment of sarcopenic obesity. Nutrition 30, 21-25.
  • Molina, G., Pessôa, M.G., Bicas, J.L., Fontanille, P., Larroche, C., Pastore, G.M. (2019). Optimization of limonene biotransformation for the production of bulk amounts of α-terpineol.Bioresource Technology. https://doi.org/10.1016/j.biortech.2019.122180
  • Nurzyńska-Wierdak, R., Grażyna, Z.(2014).Plant yield and bioactive compounds of tarragon (Artemisia dracunculus L.) affected by plant density.Acta Scientiarum Polonorum Hortorum Cultus,13(2),207–221
  • Obolskiy, D., Pischel, I., Feistel, B., Glotov, N., Heinrich, M. (2011). Artemisia dracunculus L.(tarragon): a critical review of its traditional use, chemical composition, pharmacology, and safety. Journal of Agricultural and Food Chemistry, 59(21), 11367-11384.
  • Öğretmen, Ö. Y. (2022). Determination of antioxidant activity of plant parts of Scilla bifolia L. (Forest hyacinth). Anatolian Journal of Environment and Animals, 7(1), 9-14. https://doi.org/10.35229/jaes.980980
  • Roberto D., Micucci P., Sebastian T., Graciela F., Anesini C. (2010). Antioxidant activity of limonene on normal murine lymphocytes: relation to H2O2 modulation and cell proliferation. Basic Clin. Pharmacol. Toxicol.,106(2010), pp.38 Sayyah, M., Nadjafnia, L., Kamalinejad, M. (2004). Anticonvulsant activity and chemical composition of Artemisia dracunculus L. essential oil.Journal of ethnopharmacology,94(2-3), 283-287
  • Sokal, R.R., Rohlf, F.J. (1987). Biostatistics.Francise Co, New York.
  • Singleton, V.L., Rossi, J.A. (1965). Colorimetry of Total Phenolics with Phosphomolybdic Phosphotungstic Acid Reagents, 16, 144-158.
  • Singh, H. P., Kaur, S., Mittal, S., Batish, D. R., Kohli, R. K. (2009). Essential oil of Artemisia scoparia inhibits plant growth by generating reactive oxygen species and causing oxidative damage.Journal of chemical ecology,35(2), 154-162.
  • Sun J.(2007). D-Limonene: safety and clinical applications. Alternative Med. Rev.,12(3), 259-264.
  • Suja, K. P., Jayalekshmy, A., Arumughan, C. (2005). Antioxidant activity of sesame cake extract.Food chemistry,91(2), 213-219.
  • URL–1,(2022).https://www.hurriyet.com.tr/mahmure/gallery-tarragon-whatis-how-used-ask-tarragon-herb-benefits-41960588, 2 July 2022.
  • Uzun, E. (2013). Bacterial Pathogens Causing Mortalities in The Sea Bass (Dicentrarchus labrax) and Determination of Seasonal Occurrence in The Eastern Black Sea. Master thesis, Karadeniz Technical University, The Graduate School of Natural and Applied Sciences, Trabzon, Turkey.
  • Uzun, E. Ogut, H., (2015). The isolation frequency of bacterial pathogens from sea bass (Dicentrarchus labrax) in the Southeastern Black Sea. Aquaculture, 437,30-37.
  • Valko, M., Rhodes, C. J. B., Moncol, J., Izakovic, M. M., Mazur, M. (2006). Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chemico-biological interactions,160(1), 1-40.
  • Vandanmagsar, B., Haynie, K., Wicks, S., Bermudez, E., Mendoza, T., Ribnicky, D., Cefalu, W. Mynatt, R. (2014). Artemisia dracunculus L. L. extract ameliorates insulin sensitivity by attenuating inflammatory signalling in human skeletal muscle culture. Diabetes, Obesity and Metabolism, 16, 728-738.
  • Yaichibe, T., Masanori, K., Kenichi, A. (1997). Morphological characters and essential oil in Artemisia dracunculus (French Tarragon) and Artemisia dracuncloides (Russian Tarragon).Tokyo Nogyo Daigaku Nogaku Shuho,41(4), 229-238.
  • Yaylacı E.U., (2019). Developing a differentiation technique for the pathogenic bacteria causing disease in sea bass (Dicentrarchus labrax) by using artifıcial neural networks. Doctoral Thesis, Karadeniz Technical University, The Graduate School of Natural and Applied Sciences, Trabzon, Turkey, 49–50.
Toplam 45 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Araştırma Makaleleri
Yazarlar

Ayşe Kara 0000-0002-8448-2144

Emre Çağlak 0000-0002-7376-1359

Yayımlanma Tarihi 30 Aralık 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 3 Sayı: 2

Kaynak Göster

APA Kara, A., & Çağlak, E. (2022). Phytochemical Research and Evaluation of Tarragon (Artemisia dracunculus L.) as a Food Additive. Recep Tayyip Erdogan University Journal of Science and Engineering, 3(2), 50-60. https://doi.org/10.53501/rteufemud.1160846

Taranılan Dizinler

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