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Cyclodextrin Based Nanoencapsule Applications In Foods

Yıl 2025, Cilt: 39 Sayı: 3, 694 - 707, 27.12.2025
https://doi.org/10.15316/selcukjafsci.1612121

Öz

This research explores the significance of cyclodextrin-based nanoencapsulation applications in the food industry and the benefits that this technology offers. Nanoencapsulation represents a novel technique that offers protection and enables the controlled release of bioactive compounds from environmental influences. In particular, the effects on increasing stability and preserving the functional properties of sensitive substances such as vitamins, antioxidants and flavor components are discussed within the scope of this review. The amphiphilic nature of cyclodextrins with a hydrophobic inner cavity and a hydrophilic outer surface is vital for encapsulating ingredients and enhancing their shelf life. Cyclodextrin-based nanoencapsulation has a wide application potential in the food industry. This technology offers significant advantages in terms of maintaining and improving the quality of functional foods, as well as improving the sensory and nutritional properties of bioactive ingredients. Although it has some limitations such as high costs and production difficulties, it is predicted that this technology will make a significant contribution to improving the quality of food products with further development in the future.

Kaynakça

  • Adeyeye, S. A. O., & Fayemi, O. E. (2019). Nanotechnology and food processing: Between innovations and consumer safety. Journal of Culinary Science and Technology 17(5): 435-452.
  • Agarwal, S., Jha, A., & Bhandari, V. (2018). Role of encapsulation in probiotic delivery. Current Research in Microbiology and Biotechnology 6(4): 234-240.
  • Aloğlu, H. Ş., & Öner, Z. (2010). Peyniraltı suyu proteinlerinin mikroenkapsülasyon teknolojisinde kaplama materyali olarak kullanım olanakları. Akademik Gıda 8(3): 38-42.
  • Avcı, A., & Dönmez, S. (2010). Siklodekstrinler ve Gıda Endüstrisinde Kullanımları. Gıda Dergisi 35(4): 305-312. Awuchi, C. G., Morya, S., Dendegh, T. A., Okpala, C. O. R., & Korzeniowska, M. (2022). Nanoencapsulation of food bioactive constituents and its associated processes: A revisit. Bioresource Technology Reports, 19, 101088.
  • Bayrak, A. (2006). Gıda Aromaları. Gıda Teknolojisi Derneği No: 32, 497 s.
  • Çetin, H. (2014). Karanfil uçucu yağinin siklodekstrinler ile mikroenkapsülasyonu (Master's thesis, Ankara Universitesi (Turkey)).
  • Couvreur, P., Dubernet, C., & Puisieux, F. (1995). Controlled drug delivery with nanoparticles: current possibilities and future trends. European journal of pharmaceutics and biopharmaceutics 41(1): 2-13.
  • Couvreur, P., Tulkenst, P., Roland, M., Trouet, A., & Speiser, P., (1977). Nanocapsules: a new type of lysosomotropic carrier. FEBS letters 84(2): 323-326. https://doi.org/10.1016/0014-5793(77)80717-5
  • de Vos, P., Bučko, M., Gemeiner, P., Navrátil, M., Švitel, J., Faas, M., Strand, B. L., Skjak-Braek, G., Morch, Y. A., Vikartovska, A., Lacik, I., Kollarikova, G., Orive, G., Poncelet, D., Pedraz, J. L., & Ansorge-Schumacher, M. B. (2009). Multiscale requirements for bioencapsulation in medicine and biotechnology. Biomaterials 30(13): 2559-2570. Doi:10.1016/j.biomaterials.2009.01.014
  • Dhiman, P., & Bhatia, M. (2020). Pharmaceutical applications of cyclodextrins and their derivatives. Journal of Inclusion Phenomena and Macrocyclic Chemistry 98(3): 171-186. https://doi.org/10.1007/s10847-020-01029-3
  • Donsì, F., Annunziata, M., Sessa, M., & Ferrari, G. (2011). Nanoencapsulation of essential oils to enhance their antimicrobial activity in foods. LWT-Food Science and Technology 44(9): 1908-1914. https://doi.org/10.1016/j.lwt.2011.03.003
  • Donsì, F., & Ferrari, G. (2016). Nanoencapsulation of essential oils to enhance their antimicrobial activity in foods. LWT - Food Science and Technology 64(1): 344-351.
  • Elkalla, E., Khizar, S., Tarhini, M., Lebaz, N., Zine, N., Jaffrezic-Renault, N., ... & Elaissari, A. (2023). Core-shell micro/nanocapsules: from encapsulation to applications. Journal of Microencapsulation, 40(3), 125-156.
  • Estevinho, B. N., & López-Rubio, A. (2024). Recent Advances in Encapsulation for Food Applications. Foods, 13(4), 579.
  • Fathi, M., Mozafari, M. R., & Mohebbi, M. (2014). Nanoencapsulation of food ingredients using lipid based delivery systems. Trends in food science & technology 23(1): 13-27. https://doi.org/10.1016/j.tifs.2011.08.003
  • Feng, J., Zhou, B., & Xu, Y. (2016). Nisin nanoencapsulation and its antimicrobial efficacy. Journal of Food Science and Technology 53(12): 4375-4382. https://doi.org/10.1016/B978-0-323-99546-7.00015-X
  • Gharsallaoui, A., Roudaut, G., Chambin, O., Voilley, A., & Saurel, R. (2007). Applications of spray-drying in microencapsulation of food ingredients: An overview. Food research international 40(9): 1107-1121. https://doi.org/10.1016/j.foodres.2007.07.004
  • Gökmen, S., Palamutoğlu, R., & Sarıçoban, C. (2012). Gıda endüstrisinde enkapsülasyon uygulamaları. Gıda Teknolojileri Elektronik Dergisi 7(1): 36-50.
  • Gouin, S. (2004). Microencapsulation: industrial appraisal of existing technologies and trends. Trends in food science & technology 15(7-8): 330-347. https://doi.org/10.1016/j.tifs.2003.10.005
  • Huq, T., Khan, A., & Nychas, G. J. (2019). Probiotics and nanoencapsulation. Trends in Food Science & Technology 91: 64-72.
  • Iskineyeva, A., Fazylov, S., Bakirova, R., Sarsenbekova, A., Pustolaikina, I., Seilkhanov, O., ... & Metwaly, A. M. (2022). Combined in silico and experimental investigations of resveratrol encapsulation by beta-cyclodextrin. Plants, 11(13), 1678.
  • Ju, J. (2023). Essential Oils as Antimicrobial Agents in Food Preservation. CRC Press. https://doi.org/10.1201/9781003329268
  • Kawashima, Y. (2001). The design of nanoparticles for the oral delivery of peptide and protein drugs. Expert Opinion on Drug Delivery 6(5): 557-572.
  • King, A. H. (1995). Encapsulation of food ingredients: a review of available technology, focusing on hydrocolloids. DOI: 10.1021/bk-1995-0590.ch003
  • Lesmes, U., & McClements, D. J. (2009). Structure–function relationships to guide rational design and fabrication of particulate food delivery systems. Trends in Food Science & Technology 20(10): 448-457. https://doi.org/10.1016/j.tifs.2009.05.006
  • Li, H., Cui, Y., Wang, H., Zhu, Y., & Wang, B. (2017). Preparation and application of polysulfone microcapsules containing tung oil in self-healing and self-lubricating epoxy coating. Colloids and Surfaces A: Physicochemical and Engineering Aspects 518: 181-187. https://doi.org/10.1016/j.colsurfa.2017.01.046
  • Li, S., Purdy, & W. C. (1992). Cyclodextrins and their applications in analytical chemistry. Chemical Reviews 92(6): 1457-1470.
  • Li, Z., & McClements, D. J. (2011). Influence of encapsulation technology on food functionality. Trends in Food Science & Technology 22(5): 260-269.
  • Li, J., Xu, F., Dai, Y., Zhang, J., Shi, Y., Lai, D., ... & Hu, J. (2022). A Review of Cyclodextrin Encapsulation and Intelligent Response for the Release of Curcumin. Polymers, 14(24), 5421.
  • Lima PS, Lucchese AM, Araujo-Filho HG, Menezes, PP, Araujo AA, Quintans-Junior LJ, & Quintans JS (2016). Inclusion of terpenes in cyclodextrins: Preparation, characterization and pharmacological approaches. Carbohydr. Polym. 151: 965–987. https://doi.org/10.1016/j.carbpol.2016.06.040
  • Madene, A., Jacquot, M., Scher, J., & Desobry, S. (2006). Flavour encapsulation and controlled release–a review. International journal of food science & technology 41(1): 1-21. https://doi.org/10.1111/j.1365-2621.2005.00980.x
  • Martin Del Valle, E. M. (2004). Cyclodextrins and their uses: a review. Process Biochemistry 39(9): 1033-1046. https://doi.org/10.1016/S0032-9592(03)00258-9
  • McClements, D. J. (2014). Nanoparticle-and microparticle-based delivery systems: Encapsulation, protection and release of active compounds. CRC press.
  • Mozafari, M. R. (2006). Nanocarrier technologies: Frontiers of nanotherapy. Springer Science & Business Media.
  • Neves, A. R., Queiroz, J. F., & Reis, S. (2016). Brain-targeted delivery of resveratrol using solid lipid nanoparticles functionalized with apolipoprotein E. Journal of nanobiotechnology 14: 1-11. DOI 10.1186/s12951-016-0177-x
  • Orive, G., Anitua, E., Pedraz, J. L., & Emerich, D. F. (2009). Biomaterials for promoting brain protection, repair and regeneration. Nature Reviews Neuroscience 10(9): 682-692. doi:10.1038/nrn2685
  • Pinho, E., Grootveld, M., Soares, G., & Henriques, M. (2014a). Cyclodextrins as encapsulation agents for plant bioactive compounds. Carbohydrate Polymers 101: 121–135. https://doi.org/10.1016/j.carbpol.2013.08.078
  • Quintanilla-Carvajal, M. X., Camacho-Díaz, B. H., Meraz-Torres, L. S., Chanona-Pérez, J. J., Alamilla-Beltrán, L., Jimenéz-Aparicio, A., & Gutiérrez-López, G. F. (2010). Nanoencapsulation: a new trend in food engineering processing. Food Engineering Reviews 2: 39-50. DOI 10.1007/s12393-009-9012-6
  • Rajam, R., & Subramanian, P. (2022). Encapsulation of probiotics: past, present and future. Beni-Suef University Journal of Basic and Applied Sciences, 11(1), 46.
  • Ravichandran, R. (2010). Nanotechnology applications in food and food processing: innovative green approaches, opportunities and uncertainties for global market. International Journal of Green Nanotechnology: Physics and Chemistry 1(2): P72-P96. https://doi.org/10.1080/19430871003684440
  • Ribeiro, A. M., Estevinho, B. N., & Rocha, F. (2020). Microencapsulation of vitamin D: A review. Trends in Food Science & Technology 99: 620-635.
  • Salgado, D., Guerra-Rodriguez, E., & Romero, J. (2015). Nanoencapsulation of antimicrobials. Journal of Applied Microbiology 119(1): 52-63.
  • Schardinger, F. (1903). Über thermophile Bakterien aus verschiedenen Speisen und Milch: sowie über einige Umsetzungsprodukte derselben in kohlenhydrathaltigen Nährlösungen, darunter krystallisierte Polysaccharide (Dextrine) aus Stärke. Zeitschrift für Untersuchung der Nahrungs-und Genussmittel, sowie der Gebrauchsgegenstände 6: 865-880.
  • Shah, B. R., Li, Y., Jin, W., An, Y., He, L., & Li, Z. (2014). Preparation and optimization of pickering emulsion stabilized by chitosan-tripolyphosphate nanoparticles. RSC Advances 4(41): 20877-20885. https://doi.org/10.1016/j.foodhyd.2015.07.015
  • Sharma, K., Porat, Z. E., & Gedanken, A. (2021). Designing natural polymer-based capsules and spheres for biomedical applications—a review. Polymers, 13(24), 4307.
  • Shi, C., Fang, D., Xia, S., Wang, J., Guo, Y., Lyu, L., ... & Li, W. (2023). Preparation and characterization of lemon essential oil@ β-cyclodextrin inclusion for blackberry postharvest preservation. Food Control, 154, 109979.
  • Soyuçok, A., Kılıç, B., & Kılıç, G. B. (2019). Et Ürünlerinde Enkapsülasyon Teknolojisinin Kullanımı. Mehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü Dergisi 10(1): 102-110. https://doi.org/10.29048/makufebed.530102
  • Szejtli, J. (1998). Introduction and General Overview of Cyclodextrin Chemistry. Chemical Reviews 98(5): 1743-1754.
  • Szente, L., & Szejtli, J. (2004). Cyclodextrins as food ingredients. Trends in Food Science & Technology 15: 137-142. https://doi.org/10.1016/j.tifs.2003.09.019
  • Torchilin, V. P. (2006). Nanoparticulates as drug carriers. Imperial college press.
  • Wang, N., Wang, J. Q., Wang, Y. F., & Ding, H. (2016). Preparation of sodium alginate/porous starch oreoil microcapsules. Food Sci. Technol. 9: 037–044. https://doi.org/10.1080/10408398.2018.1503590
  • Wang, H., Wang, S., Zhu, H., Wang, S., & Xing, J. (2019). Inclusion complexes of lycopene and β-cyclodextrin: Preparation, characterization, stability and antioxidant activity. Antioxidants, 8(8), 314.
  • Zhang, R., McClements, D. J., & Weiss, J. (2015). Structuring of emulsions using biopolymer-based delivery systems for functional foods. Annual Review of Food Science and Technology 6: 75-99.

Gıdalarda Siklodekstrin Bazlı Nanoenkapsül Uygulamaları

Yıl 2025, Cilt: 39 Sayı: 3, 694 - 707, 27.12.2025
https://doi.org/10.15316/selcukjafsci.1612121

Öz

Bu araştırma, siklodekstrin bazlı nanoenkapsülasyon uygulamalarının gıda endüstrisindeki önemini ve bu teknolojinin sunduğu faydaları incelemektedir. Nanoenkapsülasyon, biyoaktif bileşiklerin çevresel etkilerden korunmasını ve kontrollü salınımını sağlayan yeni bir tekniktir. Özellikle, vitaminler, antioksidanlar ve aroma bileşenleri gibi hassas maddelerin stabilitesinin artırılması ve fonksiyonel özelliklerinin korunması üzerindeki etkileri bu inceleme kapsamında ele alınmaktadır. Hidrofobik iç boşluğa ve hidrofilik dış yüzeye sahip siklodekstrinlerin amfifilik yapısı, bileşenlerin kapsüllenmesi ve raf ömrünün uzatılması için hayati önem taşımaktadır. Siklodekstrin bazlı nanoenkapsülasyon, gıda endüstrisinde geniş bir uygulama potansiyeline sahiptir. Bu teknoloji, fonksiyonel gıdaların kalitesinin korunması ve iyileştirilmesinin yanı sıra biyoaktif bileşenlerin duyusal ve besleyici özelliklerinin iyileştirilmesi açısından önemli avantajlar sunmaktadır. Yüksek maliyetler ve üretim zorlukları gibi bazı sınırlamaları olmasına rağmen, bu teknolojinin gelecekte daha da geliştirilmesiyle gıda ürünlerinin kalitesinin iyileştirilmesine önemli bir katkı sağlayacağı öngörülmektedir.

Kaynakça

  • Adeyeye, S. A. O., & Fayemi, O. E. (2019). Nanotechnology and food processing: Between innovations and consumer safety. Journal of Culinary Science and Technology 17(5): 435-452.
  • Agarwal, S., Jha, A., & Bhandari, V. (2018). Role of encapsulation in probiotic delivery. Current Research in Microbiology and Biotechnology 6(4): 234-240.
  • Aloğlu, H. Ş., & Öner, Z. (2010). Peyniraltı suyu proteinlerinin mikroenkapsülasyon teknolojisinde kaplama materyali olarak kullanım olanakları. Akademik Gıda 8(3): 38-42.
  • Avcı, A., & Dönmez, S. (2010). Siklodekstrinler ve Gıda Endüstrisinde Kullanımları. Gıda Dergisi 35(4): 305-312. Awuchi, C. G., Morya, S., Dendegh, T. A., Okpala, C. O. R., & Korzeniowska, M. (2022). Nanoencapsulation of food bioactive constituents and its associated processes: A revisit. Bioresource Technology Reports, 19, 101088.
  • Bayrak, A. (2006). Gıda Aromaları. Gıda Teknolojisi Derneği No: 32, 497 s.
  • Çetin, H. (2014). Karanfil uçucu yağinin siklodekstrinler ile mikroenkapsülasyonu (Master's thesis, Ankara Universitesi (Turkey)).
  • Couvreur, P., Dubernet, C., & Puisieux, F. (1995). Controlled drug delivery with nanoparticles: current possibilities and future trends. European journal of pharmaceutics and biopharmaceutics 41(1): 2-13.
  • Couvreur, P., Tulkenst, P., Roland, M., Trouet, A., & Speiser, P., (1977). Nanocapsules: a new type of lysosomotropic carrier. FEBS letters 84(2): 323-326. https://doi.org/10.1016/0014-5793(77)80717-5
  • de Vos, P., Bučko, M., Gemeiner, P., Navrátil, M., Švitel, J., Faas, M., Strand, B. L., Skjak-Braek, G., Morch, Y. A., Vikartovska, A., Lacik, I., Kollarikova, G., Orive, G., Poncelet, D., Pedraz, J. L., & Ansorge-Schumacher, M. B. (2009). Multiscale requirements for bioencapsulation in medicine and biotechnology. Biomaterials 30(13): 2559-2570. Doi:10.1016/j.biomaterials.2009.01.014
  • Dhiman, P., & Bhatia, M. (2020). Pharmaceutical applications of cyclodextrins and their derivatives. Journal of Inclusion Phenomena and Macrocyclic Chemistry 98(3): 171-186. https://doi.org/10.1007/s10847-020-01029-3
  • Donsì, F., Annunziata, M., Sessa, M., & Ferrari, G. (2011). Nanoencapsulation of essential oils to enhance their antimicrobial activity in foods. LWT-Food Science and Technology 44(9): 1908-1914. https://doi.org/10.1016/j.lwt.2011.03.003
  • Donsì, F., & Ferrari, G. (2016). Nanoencapsulation of essential oils to enhance their antimicrobial activity in foods. LWT - Food Science and Technology 64(1): 344-351.
  • Elkalla, E., Khizar, S., Tarhini, M., Lebaz, N., Zine, N., Jaffrezic-Renault, N., ... & Elaissari, A. (2023). Core-shell micro/nanocapsules: from encapsulation to applications. Journal of Microencapsulation, 40(3), 125-156.
  • Estevinho, B. N., & López-Rubio, A. (2024). Recent Advances in Encapsulation for Food Applications. Foods, 13(4), 579.
  • Fathi, M., Mozafari, M. R., & Mohebbi, M. (2014). Nanoencapsulation of food ingredients using lipid based delivery systems. Trends in food science & technology 23(1): 13-27. https://doi.org/10.1016/j.tifs.2011.08.003
  • Feng, J., Zhou, B., & Xu, Y. (2016). Nisin nanoencapsulation and its antimicrobial efficacy. Journal of Food Science and Technology 53(12): 4375-4382. https://doi.org/10.1016/B978-0-323-99546-7.00015-X
  • Gharsallaoui, A., Roudaut, G., Chambin, O., Voilley, A., & Saurel, R. (2007). Applications of spray-drying in microencapsulation of food ingredients: An overview. Food research international 40(9): 1107-1121. https://doi.org/10.1016/j.foodres.2007.07.004
  • Gökmen, S., Palamutoğlu, R., & Sarıçoban, C. (2012). Gıda endüstrisinde enkapsülasyon uygulamaları. Gıda Teknolojileri Elektronik Dergisi 7(1): 36-50.
  • Gouin, S. (2004). Microencapsulation: industrial appraisal of existing technologies and trends. Trends in food science & technology 15(7-8): 330-347. https://doi.org/10.1016/j.tifs.2003.10.005
  • Huq, T., Khan, A., & Nychas, G. J. (2019). Probiotics and nanoencapsulation. Trends in Food Science & Technology 91: 64-72.
  • Iskineyeva, A., Fazylov, S., Bakirova, R., Sarsenbekova, A., Pustolaikina, I., Seilkhanov, O., ... & Metwaly, A. M. (2022). Combined in silico and experimental investigations of resveratrol encapsulation by beta-cyclodextrin. Plants, 11(13), 1678.
  • Ju, J. (2023). Essential Oils as Antimicrobial Agents in Food Preservation. CRC Press. https://doi.org/10.1201/9781003329268
  • Kawashima, Y. (2001). The design of nanoparticles for the oral delivery of peptide and protein drugs. Expert Opinion on Drug Delivery 6(5): 557-572.
  • King, A. H. (1995). Encapsulation of food ingredients: a review of available technology, focusing on hydrocolloids. DOI: 10.1021/bk-1995-0590.ch003
  • Lesmes, U., & McClements, D. J. (2009). Structure–function relationships to guide rational design and fabrication of particulate food delivery systems. Trends in Food Science & Technology 20(10): 448-457. https://doi.org/10.1016/j.tifs.2009.05.006
  • Li, H., Cui, Y., Wang, H., Zhu, Y., & Wang, B. (2017). Preparation and application of polysulfone microcapsules containing tung oil in self-healing and self-lubricating epoxy coating. Colloids and Surfaces A: Physicochemical and Engineering Aspects 518: 181-187. https://doi.org/10.1016/j.colsurfa.2017.01.046
  • Li, S., Purdy, & W. C. (1992). Cyclodextrins and their applications in analytical chemistry. Chemical Reviews 92(6): 1457-1470.
  • Li, Z., & McClements, D. J. (2011). Influence of encapsulation technology on food functionality. Trends in Food Science & Technology 22(5): 260-269.
  • Li, J., Xu, F., Dai, Y., Zhang, J., Shi, Y., Lai, D., ... & Hu, J. (2022). A Review of Cyclodextrin Encapsulation and Intelligent Response for the Release of Curcumin. Polymers, 14(24), 5421.
  • Lima PS, Lucchese AM, Araujo-Filho HG, Menezes, PP, Araujo AA, Quintans-Junior LJ, & Quintans JS (2016). Inclusion of terpenes in cyclodextrins: Preparation, characterization and pharmacological approaches. Carbohydr. Polym. 151: 965–987. https://doi.org/10.1016/j.carbpol.2016.06.040
  • Madene, A., Jacquot, M., Scher, J., & Desobry, S. (2006). Flavour encapsulation and controlled release–a review. International journal of food science & technology 41(1): 1-21. https://doi.org/10.1111/j.1365-2621.2005.00980.x
  • Martin Del Valle, E. M. (2004). Cyclodextrins and their uses: a review. Process Biochemistry 39(9): 1033-1046. https://doi.org/10.1016/S0032-9592(03)00258-9
  • McClements, D. J. (2014). Nanoparticle-and microparticle-based delivery systems: Encapsulation, protection and release of active compounds. CRC press.
  • Mozafari, M. R. (2006). Nanocarrier technologies: Frontiers of nanotherapy. Springer Science & Business Media.
  • Neves, A. R., Queiroz, J. F., & Reis, S. (2016). Brain-targeted delivery of resveratrol using solid lipid nanoparticles functionalized with apolipoprotein E. Journal of nanobiotechnology 14: 1-11. DOI 10.1186/s12951-016-0177-x
  • Orive, G., Anitua, E., Pedraz, J. L., & Emerich, D. F. (2009). Biomaterials for promoting brain protection, repair and regeneration. Nature Reviews Neuroscience 10(9): 682-692. doi:10.1038/nrn2685
  • Pinho, E., Grootveld, M., Soares, G., & Henriques, M. (2014a). Cyclodextrins as encapsulation agents for plant bioactive compounds. Carbohydrate Polymers 101: 121–135. https://doi.org/10.1016/j.carbpol.2013.08.078
  • Quintanilla-Carvajal, M. X., Camacho-Díaz, B. H., Meraz-Torres, L. S., Chanona-Pérez, J. J., Alamilla-Beltrán, L., Jimenéz-Aparicio, A., & Gutiérrez-López, G. F. (2010). Nanoencapsulation: a new trend in food engineering processing. Food Engineering Reviews 2: 39-50. DOI 10.1007/s12393-009-9012-6
  • Rajam, R., & Subramanian, P. (2022). Encapsulation of probiotics: past, present and future. Beni-Suef University Journal of Basic and Applied Sciences, 11(1), 46.
  • Ravichandran, R. (2010). Nanotechnology applications in food and food processing: innovative green approaches, opportunities and uncertainties for global market. International Journal of Green Nanotechnology: Physics and Chemistry 1(2): P72-P96. https://doi.org/10.1080/19430871003684440
  • Ribeiro, A. M., Estevinho, B. N., & Rocha, F. (2020). Microencapsulation of vitamin D: A review. Trends in Food Science & Technology 99: 620-635.
  • Salgado, D., Guerra-Rodriguez, E., & Romero, J. (2015). Nanoencapsulation of antimicrobials. Journal of Applied Microbiology 119(1): 52-63.
  • Schardinger, F. (1903). Über thermophile Bakterien aus verschiedenen Speisen und Milch: sowie über einige Umsetzungsprodukte derselben in kohlenhydrathaltigen Nährlösungen, darunter krystallisierte Polysaccharide (Dextrine) aus Stärke. Zeitschrift für Untersuchung der Nahrungs-und Genussmittel, sowie der Gebrauchsgegenstände 6: 865-880.
  • Shah, B. R., Li, Y., Jin, W., An, Y., He, L., & Li, Z. (2014). Preparation and optimization of pickering emulsion stabilized by chitosan-tripolyphosphate nanoparticles. RSC Advances 4(41): 20877-20885. https://doi.org/10.1016/j.foodhyd.2015.07.015
  • Sharma, K., Porat, Z. E., & Gedanken, A. (2021). Designing natural polymer-based capsules and spheres for biomedical applications—a review. Polymers, 13(24), 4307.
  • Shi, C., Fang, D., Xia, S., Wang, J., Guo, Y., Lyu, L., ... & Li, W. (2023). Preparation and characterization of lemon essential oil@ β-cyclodextrin inclusion for blackberry postharvest preservation. Food Control, 154, 109979.
  • Soyuçok, A., Kılıç, B., & Kılıç, G. B. (2019). Et Ürünlerinde Enkapsülasyon Teknolojisinin Kullanımı. Mehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü Dergisi 10(1): 102-110. https://doi.org/10.29048/makufebed.530102
  • Szejtli, J. (1998). Introduction and General Overview of Cyclodextrin Chemistry. Chemical Reviews 98(5): 1743-1754.
  • Szente, L., & Szejtli, J. (2004). Cyclodextrins as food ingredients. Trends in Food Science & Technology 15: 137-142. https://doi.org/10.1016/j.tifs.2003.09.019
  • Torchilin, V. P. (2006). Nanoparticulates as drug carriers. Imperial college press.
  • Wang, N., Wang, J. Q., Wang, Y. F., & Ding, H. (2016). Preparation of sodium alginate/porous starch oreoil microcapsules. Food Sci. Technol. 9: 037–044. https://doi.org/10.1080/10408398.2018.1503590
  • Wang, H., Wang, S., Zhu, H., Wang, S., & Xing, J. (2019). Inclusion complexes of lycopene and β-cyclodextrin: Preparation, characterization, stability and antioxidant activity. Antioxidants, 8(8), 314.
  • Zhang, R., McClements, D. J., & Weiss, J. (2015). Structuring of emulsions using biopolymer-based delivery systems for functional foods. Annual Review of Food Science and Technology 6: 75-99.
Toplam 53 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Gıda Mühendisliği, Gıda Ambalajlama, Saklama ve İşleme, Gıda Güvenliği, İzlenebilirliği, Sertifikasyonu ve Özgünlüğü, Gıda Mikrobiyolojisi, Temel Gıda İşlemleri, Gıda Bilimleri (Diğer)
Bölüm Derleme
Yazarlar

Damla Özışık 0009-0006-9406-1518

Nihat Akın 0000-0002-0966-1126

Gönderilme Tarihi 2 Ocak 2025
Kabul Tarihi 22 Temmuz 2025
Yayımlanma Tarihi 27 Aralık 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 39 Sayı: 3

Kaynak Göster

APA Özışık, D., & Akın, N. (2025). Cyclodextrin Based Nanoencapsule Applications In Foods. Selcuk Journal of Agriculture and Food Sciences, 39(3), 694-707. https://doi.org/10.15316/selcukjafsci.1612121
AMA Özışık D, Akın N. Cyclodextrin Based Nanoencapsule Applications In Foods. Selcuk J Agr Food Sci. Aralık 2025;39(3):694-707. doi:10.15316/selcukjafsci.1612121
Chicago Özışık, Damla, ve Nihat Akın. “Cyclodextrin Based Nanoencapsule Applications In Foods”. Selcuk Journal of Agriculture and Food Sciences 39, sy. 3 (Aralık 2025): 694-707. https://doi.org/10.15316/selcukjafsci.1612121.
EndNote Özışık D, Akın N (01 Aralık 2025) Cyclodextrin Based Nanoencapsule Applications In Foods. Selcuk Journal of Agriculture and Food Sciences 39 3 694–707.
IEEE D. Özışık ve N. Akın, “Cyclodextrin Based Nanoencapsule Applications In Foods”, Selcuk J Agr Food Sci, c. 39, sy. 3, ss. 694–707, 2025, doi: 10.15316/selcukjafsci.1612121.
ISNAD Özışık, Damla - Akın, Nihat. “Cyclodextrin Based Nanoencapsule Applications In Foods”. Selcuk Journal of Agriculture and Food Sciences 39/3 (Aralık2025), 694-707. https://doi.org/10.15316/selcukjafsci.1612121.
JAMA Özışık D, Akın N. Cyclodextrin Based Nanoencapsule Applications In Foods. Selcuk J Agr Food Sci. 2025;39:694–707.
MLA Özışık, Damla ve Nihat Akın. “Cyclodextrin Based Nanoencapsule Applications In Foods”. Selcuk Journal of Agriculture and Food Sciences, c. 39, sy. 3, 2025, ss. 694-07, doi:10.15316/selcukjafsci.1612121.
Vancouver Özışık D, Akın N. Cyclodextrin Based Nanoencapsule Applications In Foods. Selcuk J Agr Food Sci. 2025;39(3):694-707.

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