Asparuh Nikolov currently works at the Institute for Scientific Research, Medical University of Pleven. Asparuh does research in Internal Medicine (General Medicine), Diabetology and Cardiology. His research focuses on investigation of the immunological aspects of normal and pathological connective tissue turnover in patients with arterial hypertension, diabetes mellitus and heart failure. (Extracellular matrix metabolism in pathological conditions). Most recent studies are devoted on MMP/TIMPs.