Evaluation of THC and CBD Factors in Cannabis

Year 2022, , 1092 - 1104, 18.07.2022

Ayşegül Beşir , Nurdan Yazıcı Bektaş , Mustafa Mortaş , Fehmi Yazıcı

https://doi.org/10.47495/okufbed.1089331

Cited By: 1

Abstract

Cannabis has been used for different purposes since the past, and although the interest in cannabis is increasing day by day, the cannabis plant has been avoided for a while. Underlying the consumer's negative opinion of hemp is the psychoactive substance content of the plant. Contrary to popular belief, cannabis cultivated for industrial purposes is a cannabis variety with reduced psychoactive substance content and legal limits to support consumption. Although trans-Δ9-tetrahydrocannabinol (THC) in cannabis, which is responsible for the psychoactive effect, is an objectionable component that should be considered in industrial cannabis production, cannabidiol (CBD), which has the same molecular weight, has analgesic for chronic and non-chronic pain, antiepileptic, antibacterial, anti-inflammatory, anticarcinogenic, antidiabetic, antidepressant properties. THC component is not found in cannabis seeds, which are used as food for protein source purposes. In this study, the chemical properties of trans-Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) compounds, which have the same molecular properties, were compiled by examining their effects on health, applicable legal limits, and research on compounds.

Keywords

CBD, THC, Hemp, Tetrahydrocannabinol, Cannabidiol, Cannabis

Kenevirde THC ve CBD Faktörlerinin Değerlendirilmesi

Abstract

Kenevir geçmişten beri değişik amaçlarla kullanılmış ve günümüzde de kenevire olan ilgi giderek artmasına karşın bir dönem boyunca kenevir bitkisinden uzak kalınmıştır. Tüketicinin kenevire karşı olumsuz düşüncesinin sebebi, bitkinin psikoaktif madde içeriğine sahip olmasıdır. Sanılanın aksine, endüstriyel amaçla ekilen kenevir, psikoaktif madde içeriği azaltılmış ve tüketimi destekleyici olarak yasal sınırları belirlenmiş kenevir çeşididir. Kenevir bünyesinde bulunan ve psikoaktif etkiden sorumlu trans-Δ9-tetrahidrokannabinol (THC), endüstriyel kenevir üretiminde dikkat edilmesi gereken sakıncalı bir bileşen olmasına karşın aynı molekül ağırlığına sahip olan kannabidiol (CBD) ise kronik ve nonkronik ağrılar için analjezik, antiepileptik, antibakteriyel, antiinflamatuar, antikanserojen, antidiyabetik, antidepresan özellik gösteren ve psikoaktif olmayan bir bileşiktir. Protein kaynağı amaçlı gıda olarak kullanılan kenevir tohumunda ise THC bileşenine rastlanmamaktadır. Bu çalışmada, aynı moleküler özelliğe sahip olan trans-Δ9-tetrahidrokannabinol (THC) ve kannabidiol (CBD) bileşiklerinin kimyasal özellikleri, sağlık üzerine etkileri, ilgili yasal sınırlar ve bileşikler üzerine yapılan araştırmalar incelenerek derlenmiştir.

Keywords

CBD, THC, Kenevir, Tetrahidrokannabinol, Kannabidiol, Cannabis

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