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A REVIEW OF THE GLOBAL BURDEN OF CHRONIC KIDNEY DISEASE

Yıl 2024, , 354 - 365, 01.11.2024
https://doi.org/10.35232/estudamhsd.1475552

Öz

The top 10 causes of death globally account for more than half of all deaths. Kidney diseases rose from 13th in 2000 to 10th in 2019. Chronic kidney disease (CKD) has risen from 14th to 11th among Level 3 causes of death and is projected to rise to 5th place in 2040. The number of patients receiving renal replacement therapy (RRT) in the world in 2010 was 2.6 million, calculated as 379 people per million population. This number increased to 3.9 million in 2017 and is estimated to increase to 5.4 million in 2030. For kidney transplantation, one of the RRTs, there are some challenges, such as low socioeconomic status. Limited access to RRT results in more than 2 million deaths each year, with most of these deaths occurring in low- and middle-low-income countries. CKD reduces an individual’s quality of life, increases psychosocial problems, and leads to significant employment-related problems. Moreover, employment is negatively affected not only by CKD but also by hemodialysis/peritoneal dialysis. CKD also leads to high treatment costs and loss of productivity due to reduced labor force. When CKD is evaluated with some economic, labor, quality of life and burden rates, it’s reported that its global burden is increasing, and RRT should be considered. The aim of this review is to examine the global importance of the burden of CKD, its place in Türkiye with data and to draw the attention of health professionals and decision makers by emphasizing the increasing importance of the issue.

Kaynakça

  • Birleşmiş Milletler [Internet]. Sürdürülebilir Kalkınma Amaçları 3: Sağlık ve Kaliteli Yaşam. [cited 2024 Mar 1]. Available from: https://turkiye.un.org/tr/sdgs/3
  • GBD 2016 Disease and Injury Incidence and Prevalence Collaborators (2017). Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet, 2017;390(10100):1211-59. doi:10.1016/S0140-6736(17)32154-2.
  • Foreman KJ, Marquez N, Dolgert A, Fukutaki K, Fullman N, McGaughey M, et al. Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016–40 for 195 countries and territories. Lancet. 2018;392(10159):2052-90. doi:10.1016/S0140-6736(18)31694-5.
  • Collaboration GCKD. Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2020;395(10225):709-33. doi:10.1016/S0140-6736(20)30045-3.
  • Hoste EAJ, Kellum JA, Selby NM, Zarbock A, Palevsky PM, Bagshaw SM, et al. Global epidemiology and outcomes of acute kidney injury. Nat Rev Nephrol. 2018;14(10):607-25. doi:10.1038/s41581-018-0052-0.
  • Rewa O, Bagshaw SM. Acute Kidney Injury-Epidemiology, Outcomes and Economics. Nat Rev Nephrol. 2014;10(4):193-207. doi:10.1038/nrneph.2013.282.
  • Qian X, Wan J, Xu J, Liu C, Zhong M, Zhang J, et al. Epidemiological Trends of Urolithiasis at the Global, Regional, and National Levels: A Population-Based Study. Int J Clin Pract. 2022;2022:6807203. doi:10.1155/2022/6807203.
  • World Health Organization [Internet]. The top 10 causes of death. [cited 2023 Nov 22]. Available from: https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death
  • Medscape [Internet]. Pradeep A;2023. Chronic Kidney Disease (CKD): Practice Essentials, Pathophysiology, Etiology [cited 2023 Nov 22]. Available from: https://emedicine.medscape.com/article/238798-overview?form=fpf
  • O’Hare AM, Choi AI, Bertenthal D, Bacchetti P, Garg AX, Kaufman JS, et al. Age affects outcomes in chronic kidney disease. J Am Soc Nephrol JASN [Internet]. 2007 [cited 2024 Mar 31];18(10):2758–65. Available from: https://journals.lww.com/jasn/fulltext/2007/10000/age_affects_outcomes_in_chronic_kidney_disease.19.aspx
  • Kovesdy CP. Epidemiology of chronic kidney disease: an update 2022. Kidney Int Suppl. 2022;12(1):7–11. doi: 10.1016/j.kisu.2021.11.003.
  • Türkiye Böbrek Hastalıkları Önleme ve Kontrol Programı Eylem Planı (2018-2023) [Internet]. T.C. Sağlık Bakanlığı Halk Sağlığı Genel Müdürlüğü; 2018 [cited 2024 Mar 13]. Available from: https://hsgm.saglik.gov.tr/depo/birimler/kronik-hastaliklar-ve-yasli-sagligi-db/Dokumanlar/Kitaplar/Turkiye_Bobrek_Hastaliklari_Onleme_ve_Kontrol_Programi_2018-2023.pdf
  • Global Burden of Disease Collaborative Network. [Internet]. Global Burden of Disease Study 2019 (GBD 2019) Results. Seattle, United States: Institute for Health Metrics and Evaluation (IHME), 2020. [cited 2023 Nov 22]. Available from https://vizhub.healthdata.org/gbd-results
  • Ying M, Shao X, Qin H, Yin P, Lin Y, Wu J, et al. Disease Burden and Epidemiological Trends of Chronic Kidney Disease at the Global, Regional, National Levels from 1990 to 2019. Nephron. 2024;148(2):113-23. doi: 10.1159/000534071.
  • Song J, Pan T, Xu Z, Yi W, Pan R, Cheng J, et al. A systematic analysis of chronic kidney disease burden attributable to lead exposure based on the global burden of disease study 2019. Sci Total Environ. 2024;908:168189. doi:10.1016/j.scitotenv.2023.168189.
  • Xie Y, Bowe B, Mokdad AH, Xian H, Yan Y, Li T, et al. Analysis of the Global Burden of Disease study highlights the global, regional, and national trends of chronic kidney disease epidemiology from 1990 to 2016. Kidney Int. 2018;94(3):567-81. doi:10.1016/j.kint.2018.04.011.
  • T.C. Sağlık Bakanlığı [Internet]. Sağlık İstatistikleri Yıllığı 2021 [cited 2024 Mar 1]. Available from: https://dosyasb.saglik.gov.tr/Eklenti/45316/0/siy2021-turkcepdf.pdf
  • Merck Manuals Professional Edition [Internet]. Overview of Renal Replacement Therapy - Genitourinary Disorders [cited 2024 Mar 13]. Available from: https://www.merckmanuals.com/professional/genitourinary-disorders/renal-replacement-therapy/overview-of-renal-replacement-therapy
  • International Society of Nephrology [Internet]. Brussels, Belgium: Bello A, Okpechi I, Levin A, Ye F, Saad S, Zaidi D, et al. ISN–Global Kidney Health Atlas: A report by the International Society of Nephrology: An Assessment of Global Kidney Health Care Status focussing on Capacity, Availability, Accessibility, Affordability and Outcomes of Kidney Disease; 2023 [cited 2023 Nov 29]. Available from: https://www.theisn.org/initiatives/global-kidney-health-atlas/#publications
  • NHS-UK [Internet]. Dialysis – Overview; 2017 [cited 2024 Apr 12]. Available from: https://www.nhs.uk/conditions/dialysis/
  • NHS-UK [Internet]. Kidney transplant – Overview; 2017 [cited 2024 Mar 29]. Available from: https://www.nhs.uk/conditions/kidney-transplant/
  • Liyanage T, Ninomiya T, Jha V, Neal B, Patrice HM, Okpechi I, et al. Worldwide access to treatment for end-stage kidney disease: a systematic review. Lancet. 2015;385(9981):1975-82. doi:10.1016/S0140-6736(14)61601-9.
  • Jager KJ, Kovesdy C, Langham R, Rosenberg M, Jha V, Zoccali C. A single number for advocacy and communication—worldwide more than 850 million individuals have kidney diseases. Kidney Int. 2019;96(5):1048-50. doi:10.1016/j.kint.2019.07.012
  • Bello AK, Okpechi IG, Osman MA, Cho Y, Htay H, Jha V, et al. Epidemiology of haemodialysis outcomes. Nat Rev Nephrol. 2022;18(6):378-95. doi:10.1038/s41581-022-00542-7
  • United States Renal Data System [Internet]. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases. 2022 USRDS Annual Data Report: Epidemiology of kidney disease in the United States; 2022 [cited 2024 Apr 10]. Available from: https://usrds-adr.niddk.nih.gov/2022
  • Crews DC, Bello AK, Saadi G; World Kidney Day Steering Committee. Burden, Access, and Disparities in Kidney Disease. Braz J Med Biol Res. 2019;52(3):e8338. doi:10.1590/1414-431X20198338.
  • Garcia-Garcia G, Jha V; World Kidney Day Steering Committee. Chronic kidney disease in disadvantaged populations. Braz J Med Biol Res. 2015;48(5):377-81. doi:10.1590/1414-431X20144519.
  • Jha V, Al-Ghamdi SMG, Li G, Wu MS, Stafylas P, Retat L, et al. Global Economic Burden Associated with Chronic Kidney Disease: A Pragmatic Review of Medical Costs for the Inside CKD Research Programme. Adv Ther. 2023;40(10):4405-20. doi:10.1007/s12325-023-02608-9.
  • TÜİK [Internet]. Sağlık Harcamaları İstatistikleri; 2022. [cited 2024 Mar 1]. Available from: https://data.tuik.gov.tr/Bulten/Index?p=Saglik-Harcamalari-Istatistikleri-2022-49676
  • Kirkeskov L, Carlsen RK, Lund T, Buus NH. Employment of patients with kidney failure treated with dialysis or kidney transplantation—a systematic review and meta-analysis. BMC Nephrol. 2021;22(1):348. doi:10.1186/s12882-021-02552-2.
  • van der Mei SF, Alma MA, de Rijk AE, Brouwer S, Gansevoort RT, Franssen CFM, et al. Barriers to and Facilitators of Sustained Employment: A Qualitative Study of Experiences in Dutch Patients With CKD. Am J Kidney Dis. 2021;78(6):780-92. doi:10.1053/j.ajkd.2021.04.008.
  • Alma MA, van der Mei SF, Brouwer S, Hilbrands LB, van der Boog PJM, Uiterwijk H, et al. Sustained employment, work disability and work functioning in CKD patients: a cross-sectional survey study. J Nephrol. 2023;36(3):731-43. doi:10.1007/s40620-022-01476-w.
  • Sharma S, Kalra D, Rashid I, Mehta S, Maity MK, Wazir K, et al. Assessment of Health-Related Quality of Life in Chronic Kidney Disease Patients: A Hospital-Based Cross-Sectional Study. Medicina (Kaunas). 2023;59(10):1788. doi:10.3390/medicina59101788.
  • Jesky MD, Dutton M, Dasgupta I, Yadav P, Ng KP, Fenton A, et al. Health-Related Quality of Life Impacts Mortality but Not Progression to End-Stage Renal Disease in Pre-Dialysis Chronic Kidney Disease: A Prospective Observational Study. PLoS One. 2016;11(11):e0165675. doi:10.1371/journal.pone.0165675.
  • Kim S, Nigatu Y, Araya T, Assefa Z, Dereje N. Health related quality of life (HRQOL) of patients with End Stage Kidney Disease (ESKD) on hemodialysis in Addis Ababa, Ethiopia: a cross-sectional study. BMC Nephrol. 2021;22(1):280. doi:10.1186/s12882-021-02494-9.
  • Fletcher BR, Damery S, Aiyegbusi OL, Anderson N, Calvert M, Cockwell P, et al. Symptom burden and health-related quality of life in chronic kidney disease: A global systematic review and meta-analysis. PLoS Med. 2022;19(4):e1003954. doi:10.1371/journal.pmed.1003954.
  • Mahato SKS, Apidechkul T, Sriwongpan P, Hada R, Sharma GN, Nayak SK, et al. Factors associated with quality of life among chronic kidney disease patients in Nepal: a cross-sectional study. Health Qual Life Outcomes. 2020;18(1):207. doi:10.1186/s12955-020-01458-1.
  • Mayo Clinic [Internet]. Chronic kidney disease - Symptoms and causes [cited 2024 Apr 13]. Available from: https://www.mayoclinic.org/diseases-conditions/chronic-kidney-disease/symptoms-causes/syc-20354521

KRONİK BÖBREK HASTALIĞININ KÜRESEL YÜKÜNÜN İNCELENMESİ

Yıl 2024, , 354 - 365, 01.11.2024
https://doi.org/10.35232/estudamhsd.1475552

Öz

Küresel ölçekteki ilk 10 ölüm sebebi, tüm ölümlerin yarısından fazlasını oluşturmaktadır. Böbrek hastalıkları 2000 yılında bu listede 13. sıradayken, 2019’da 10. sıraya yükselmiştir. Kronik böbrek hastalığı (KBH) düzey 3 ölüm nedenleri listesinde 14. sıradan 11’e yükselmiş olup 2040’ta 5. sıraya çıkacağı öngörülmektedir. Dünyada 2010’da böbrek replasman tedavisi (BRT) alan hasta sayısı 2,6 milyon olup milyon nüfus başına 379 kişi olarak hesaplanmıştır. Bu sayının 2017’de 3,9 milyona yükseldiği, 2030’da 5,4 milyona çıkacağı tahmin edilmektedir. BRT’lerden biri olan böbrek nakli için düşük sosyoekonomik durum gibi bazı güçlükler bulunmaktadır. BRT’ye erişimin sınırlı kalmasıyla her yıl 2 milyondan fazla insan yaşamını yitirmekte ve bu ölümlerin çoğu düşük ve orta-düşük gelirli ülkelerde meydana gelmektedir. KBH, bireyin yaşam kalitesini düşürmekte, psikososyal sorunlarını artırmakta ve istihdamla ilgili önemli sorunlara yol açmaktadır. Ayrıca istihdam sadece KBH’den değil, hemodiyaliz/periton diyalizinden de olumsuz etkilenmektedir. KBH yüksek tedavi maliyetlerine ve azalan iş gücü nedeniyle üretkenlik kaybına da yol açmaktadır. KBH ekonomik, iş gücü, yaşam kalitesi ve yüke dair bazı hızlarla değerlendirildiğinde; küresel yükünün arttığı ve BRT’nin mutlaka göz önünde bulundurulması gerektiği bildirilmektedir. Bu derleme ile KBH yükünün küresel öneminin incelenmesi, verilerle Türkiye’deki yeri, konunun artan öneminin vurgulanarak sağlık profesyonellerinin ve karar vericilerin dikkatinin çekilmesi amaçlanmıştır.

Etik Beyan

Derleme türünde bir çalışma olduğu için etik kurul iznine gerek duyulmamıştır.

Destekleyen Kurum

Herhangi bir kurumdan destek alınmamıştır.

Kaynakça

  • Birleşmiş Milletler [Internet]. Sürdürülebilir Kalkınma Amaçları 3: Sağlık ve Kaliteli Yaşam. [cited 2024 Mar 1]. Available from: https://turkiye.un.org/tr/sdgs/3
  • GBD 2016 Disease and Injury Incidence and Prevalence Collaborators (2017). Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet, 2017;390(10100):1211-59. doi:10.1016/S0140-6736(17)32154-2.
  • Foreman KJ, Marquez N, Dolgert A, Fukutaki K, Fullman N, McGaughey M, et al. Forecasting life expectancy, years of life lost, and all-cause and cause-specific mortality for 250 causes of death: reference and alternative scenarios for 2016–40 for 195 countries and territories. Lancet. 2018;392(10159):2052-90. doi:10.1016/S0140-6736(18)31694-5.
  • Collaboration GCKD. Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2020;395(10225):709-33. doi:10.1016/S0140-6736(20)30045-3.
  • Hoste EAJ, Kellum JA, Selby NM, Zarbock A, Palevsky PM, Bagshaw SM, et al. Global epidemiology and outcomes of acute kidney injury. Nat Rev Nephrol. 2018;14(10):607-25. doi:10.1038/s41581-018-0052-0.
  • Rewa O, Bagshaw SM. Acute Kidney Injury-Epidemiology, Outcomes and Economics. Nat Rev Nephrol. 2014;10(4):193-207. doi:10.1038/nrneph.2013.282.
  • Qian X, Wan J, Xu J, Liu C, Zhong M, Zhang J, et al. Epidemiological Trends of Urolithiasis at the Global, Regional, and National Levels: A Population-Based Study. Int J Clin Pract. 2022;2022:6807203. doi:10.1155/2022/6807203.
  • World Health Organization [Internet]. The top 10 causes of death. [cited 2023 Nov 22]. Available from: https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death
  • Medscape [Internet]. Pradeep A;2023. Chronic Kidney Disease (CKD): Practice Essentials, Pathophysiology, Etiology [cited 2023 Nov 22]. Available from: https://emedicine.medscape.com/article/238798-overview?form=fpf
  • O’Hare AM, Choi AI, Bertenthal D, Bacchetti P, Garg AX, Kaufman JS, et al. Age affects outcomes in chronic kidney disease. J Am Soc Nephrol JASN [Internet]. 2007 [cited 2024 Mar 31];18(10):2758–65. Available from: https://journals.lww.com/jasn/fulltext/2007/10000/age_affects_outcomes_in_chronic_kidney_disease.19.aspx
  • Kovesdy CP. Epidemiology of chronic kidney disease: an update 2022. Kidney Int Suppl. 2022;12(1):7–11. doi: 10.1016/j.kisu.2021.11.003.
  • Türkiye Böbrek Hastalıkları Önleme ve Kontrol Programı Eylem Planı (2018-2023) [Internet]. T.C. Sağlık Bakanlığı Halk Sağlığı Genel Müdürlüğü; 2018 [cited 2024 Mar 13]. Available from: https://hsgm.saglik.gov.tr/depo/birimler/kronik-hastaliklar-ve-yasli-sagligi-db/Dokumanlar/Kitaplar/Turkiye_Bobrek_Hastaliklari_Onleme_ve_Kontrol_Programi_2018-2023.pdf
  • Global Burden of Disease Collaborative Network. [Internet]. Global Burden of Disease Study 2019 (GBD 2019) Results. Seattle, United States: Institute for Health Metrics and Evaluation (IHME), 2020. [cited 2023 Nov 22]. Available from https://vizhub.healthdata.org/gbd-results
  • Ying M, Shao X, Qin H, Yin P, Lin Y, Wu J, et al. Disease Burden and Epidemiological Trends of Chronic Kidney Disease at the Global, Regional, National Levels from 1990 to 2019. Nephron. 2024;148(2):113-23. doi: 10.1159/000534071.
  • Song J, Pan T, Xu Z, Yi W, Pan R, Cheng J, et al. A systematic analysis of chronic kidney disease burden attributable to lead exposure based on the global burden of disease study 2019. Sci Total Environ. 2024;908:168189. doi:10.1016/j.scitotenv.2023.168189.
  • Xie Y, Bowe B, Mokdad AH, Xian H, Yan Y, Li T, et al. Analysis of the Global Burden of Disease study highlights the global, regional, and national trends of chronic kidney disease epidemiology from 1990 to 2016. Kidney Int. 2018;94(3):567-81. doi:10.1016/j.kint.2018.04.011.
  • T.C. Sağlık Bakanlığı [Internet]. Sağlık İstatistikleri Yıllığı 2021 [cited 2024 Mar 1]. Available from: https://dosyasb.saglik.gov.tr/Eklenti/45316/0/siy2021-turkcepdf.pdf
  • Merck Manuals Professional Edition [Internet]. Overview of Renal Replacement Therapy - Genitourinary Disorders [cited 2024 Mar 13]. Available from: https://www.merckmanuals.com/professional/genitourinary-disorders/renal-replacement-therapy/overview-of-renal-replacement-therapy
  • International Society of Nephrology [Internet]. Brussels, Belgium: Bello A, Okpechi I, Levin A, Ye F, Saad S, Zaidi D, et al. ISN–Global Kidney Health Atlas: A report by the International Society of Nephrology: An Assessment of Global Kidney Health Care Status focussing on Capacity, Availability, Accessibility, Affordability and Outcomes of Kidney Disease; 2023 [cited 2023 Nov 29]. Available from: https://www.theisn.org/initiatives/global-kidney-health-atlas/#publications
  • NHS-UK [Internet]. Dialysis – Overview; 2017 [cited 2024 Apr 12]. Available from: https://www.nhs.uk/conditions/dialysis/
  • NHS-UK [Internet]. Kidney transplant – Overview; 2017 [cited 2024 Mar 29]. Available from: https://www.nhs.uk/conditions/kidney-transplant/
  • Liyanage T, Ninomiya T, Jha V, Neal B, Patrice HM, Okpechi I, et al. Worldwide access to treatment for end-stage kidney disease: a systematic review. Lancet. 2015;385(9981):1975-82. doi:10.1016/S0140-6736(14)61601-9.
  • Jager KJ, Kovesdy C, Langham R, Rosenberg M, Jha V, Zoccali C. A single number for advocacy and communication—worldwide more than 850 million individuals have kidney diseases. Kidney Int. 2019;96(5):1048-50. doi:10.1016/j.kint.2019.07.012
  • Bello AK, Okpechi IG, Osman MA, Cho Y, Htay H, Jha V, et al. Epidemiology of haemodialysis outcomes. Nat Rev Nephrol. 2022;18(6):378-95. doi:10.1038/s41581-022-00542-7
  • United States Renal Data System [Internet]. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases. 2022 USRDS Annual Data Report: Epidemiology of kidney disease in the United States; 2022 [cited 2024 Apr 10]. Available from: https://usrds-adr.niddk.nih.gov/2022
  • Crews DC, Bello AK, Saadi G; World Kidney Day Steering Committee. Burden, Access, and Disparities in Kidney Disease. Braz J Med Biol Res. 2019;52(3):e8338. doi:10.1590/1414-431X20198338.
  • Garcia-Garcia G, Jha V; World Kidney Day Steering Committee. Chronic kidney disease in disadvantaged populations. Braz J Med Biol Res. 2015;48(5):377-81. doi:10.1590/1414-431X20144519.
  • Jha V, Al-Ghamdi SMG, Li G, Wu MS, Stafylas P, Retat L, et al. Global Economic Burden Associated with Chronic Kidney Disease: A Pragmatic Review of Medical Costs for the Inside CKD Research Programme. Adv Ther. 2023;40(10):4405-20. doi:10.1007/s12325-023-02608-9.
  • TÜİK [Internet]. Sağlık Harcamaları İstatistikleri; 2022. [cited 2024 Mar 1]. Available from: https://data.tuik.gov.tr/Bulten/Index?p=Saglik-Harcamalari-Istatistikleri-2022-49676
  • Kirkeskov L, Carlsen RK, Lund T, Buus NH. Employment of patients with kidney failure treated with dialysis or kidney transplantation—a systematic review and meta-analysis. BMC Nephrol. 2021;22(1):348. doi:10.1186/s12882-021-02552-2.
  • van der Mei SF, Alma MA, de Rijk AE, Brouwer S, Gansevoort RT, Franssen CFM, et al. Barriers to and Facilitators of Sustained Employment: A Qualitative Study of Experiences in Dutch Patients With CKD. Am J Kidney Dis. 2021;78(6):780-92. doi:10.1053/j.ajkd.2021.04.008.
  • Alma MA, van der Mei SF, Brouwer S, Hilbrands LB, van der Boog PJM, Uiterwijk H, et al. Sustained employment, work disability and work functioning in CKD patients: a cross-sectional survey study. J Nephrol. 2023;36(3):731-43. doi:10.1007/s40620-022-01476-w.
  • Sharma S, Kalra D, Rashid I, Mehta S, Maity MK, Wazir K, et al. Assessment of Health-Related Quality of Life in Chronic Kidney Disease Patients: A Hospital-Based Cross-Sectional Study. Medicina (Kaunas). 2023;59(10):1788. doi:10.3390/medicina59101788.
  • Jesky MD, Dutton M, Dasgupta I, Yadav P, Ng KP, Fenton A, et al. Health-Related Quality of Life Impacts Mortality but Not Progression to End-Stage Renal Disease in Pre-Dialysis Chronic Kidney Disease: A Prospective Observational Study. PLoS One. 2016;11(11):e0165675. doi:10.1371/journal.pone.0165675.
  • Kim S, Nigatu Y, Araya T, Assefa Z, Dereje N. Health related quality of life (HRQOL) of patients with End Stage Kidney Disease (ESKD) on hemodialysis in Addis Ababa, Ethiopia: a cross-sectional study. BMC Nephrol. 2021;22(1):280. doi:10.1186/s12882-021-02494-9.
  • Fletcher BR, Damery S, Aiyegbusi OL, Anderson N, Calvert M, Cockwell P, et al. Symptom burden and health-related quality of life in chronic kidney disease: A global systematic review and meta-analysis. PLoS Med. 2022;19(4):e1003954. doi:10.1371/journal.pmed.1003954.
  • Mahato SKS, Apidechkul T, Sriwongpan P, Hada R, Sharma GN, Nayak SK, et al. Factors associated with quality of life among chronic kidney disease patients in Nepal: a cross-sectional study. Health Qual Life Outcomes. 2020;18(1):207. doi:10.1186/s12955-020-01458-1.
  • Mayo Clinic [Internet]. Chronic kidney disease - Symptoms and causes [cited 2024 Apr 13]. Available from: https://www.mayoclinic.org/diseases-conditions/chronic-kidney-disease/symptoms-causes/syc-20354521
Toplam 38 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlığın Geliştirilmesi
Bölüm Derlemeler
Yazarlar

Murat Özbek 0000-0002-6875-4082

Nüket Paksoy Erbaydar 0000-0001-8004-4342

Yayımlanma Tarihi 1 Kasım 2024
Gönderilme Tarihi 8 Mayıs 2024
Kabul Tarihi 21 Ağustos 2024
Yayımlandığı Sayı Yıl 2024

Kaynak Göster

Vancouver Özbek M, Paksoy Erbaydar N. KRONİK BÖBREK HASTALIĞININ KÜRESEL YÜKÜNÜN İNCELENMESİ. ESTÜDAM Halk Sağlığı Dergisi. 2024;9(3):354-65.

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