PROPOLİSİN BİYOAKTİF BİLEŞENLERİ ÜZERİNE EKSTRAKSİYON YÖNTEMLERİNİN VE EKSTRAKSİYON DEĞİŞKENLERİNİN ETKİLERİ

Öz

Propolis içeriğinde bulundurduğu biyoaktif bileşenler sayesinde antik çağlardan beri geleneksel tıpta kullanılan, günümüzde ise zengin içeriği sayesinde çok sayıda çalışmaya konu olmuş ve olacak bir arı ürünüdür. Doğal antioksidan ve antimikrobiyal maddelere olan ilgi tüketicinin bilinçlenmesi ile artmaktadır. Bilimin bir şeyi etkili ve en verimli yapma çabası biyoaktif bileşenlerin ekstraksiyonunu konu alan birçok çalışmaya yol açmıştır. Propolisten biyoaktif bileşenlerin ekstraksiyonunu inceleyen, geleneksel metotlardan modern tekniklere kadar birçok yöntemin kullanıldığı araştırmalar bu çalışmada incelenmiş olup, yöntemlerin birbirine karşı etkinliği vurgulanmıştır. Farklı çözücü tiplerinin, farklı ekstraksiyon süresi ve sıcaklıklarının araştırdığı çalışmalar literatürde mevcuttur. Ekstraksiyon işlemine etki eden birçok değişkenin mevcut olması nedeniyle propolis ekstraksiyonunda ekstraksiyon değişkenlerinin optimizasyonu konu alan çalışmalara ihtiyaç duyulmaktadır.

Anahtar Kelimeler

• Propolis
• ekstraksiyon
• biyoaktif bileşen

EFFECTS OF EXTRACTION METHODS AND EXTRACTION VARIABLES ON BIOACTIVE COMPOUNDS OF PROPOLIS

Öz

Propolis is a bee product that has been used in traditional medicine since ancient times due to its bioactive components, and has been and will be the subject of many studies today because of its rich content. The interest in natural antioxidant and antimicrobial substances is increasing with the awareness of the consumer. The effort of science to make something effective and most efficient has led to many studies on the extraction of bioactive components. Studies investigating the extraction of bioactive components from propolis, using many methods from traditional methods to modern techniques, were examined in this study, and the effectiveness of this methods agains each others were emphasized. There are lots of studies in the literature investigating different solvent types, extraction times and temperatures. Since there are many variables affecting the extraction process, studies on optimization of extraction variables in propolis extraction are needed.

Anahtar Kelimeler

• Propolis
• extraction
• bioactive compounds

Kaynakça

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