KONVANSİYONEL EKSTRAKSİYONA ALTERNATİF: YEŞİL TEKNOLOJİLER

Öz

Ekstraksiyon, endüstriyel uygulamalar ve analitik amaçlar için oldukça önemlidir. Bu alandaki çalışmalar çoğunlukla gıdaların fonksiyonel özelliklerinin zenginleştirilmesinde kullanılan antosiyanin, fenolik bileşikler gibi gıda bileşiklerinin eldesinde yoğunlaşmaktadır. Bu noktada, çalışılan ekstraksiyon tekniğinin çevre dostu olması yanında, ekstraksiyonu hedeflenen bileşik üzerinde meydana gelebilecek olumsuz etkilerin de azaltılması önem taşımaktadır. Bu amaçla birçok yeni teknik geliştirilmekte ve çeşitli gıdalarda çalışmalar yürütülmektedir. Son yıllarda, geleneksel ekstraksiyon yöntemlerine alternatif olarak geliştirilen yeşil ekstraksiyon yöntemleri ile solvent kullanımının ve ekstraksiyon süresinin azaltılması yanında verimin arttırılması da hedeflenmektedir. Bu derleme, son yıllarda sıklıkla kullanılan yeşil ekstraksiyon tekniklerinin (mikrodalga, ultrases, yüksek basınç, vurgulu elektrik alan, ohmik ve süperkritik akışkan ekstraksiyon) prensiplerine, avantajlarına ve kullanım alanlarına odaklanmaktadır.

Anahtar Kelimeler

• : Mikrodalga destekli ekstraksiyon,ultrases destekli ekstraksiyon,ohmik destekli ekstraksiyon,vurgulu elektrik alan destekli ekstraksiyon,yüksek basınç destekli ekstraksiyon,süperkritik akışkan ekstraksiyon

ALTERNATIVE TO CONVENTIONAL EXTRACTION: GREEN TECHNOLOGIES

Öz

Extraction is an important method for analytical and industrial applications. The studies related to this subject mostly focus on the extraction of compounds such as anthocyanins, phenolic compounds which can be used for the production of functional foods. It is important to protect not only the extracted compounds from the adverse effects of extraction but also the environment by employing green extraction techniques. Hence, new technologies are being developed and studies are being conducted with different foods. Recently, it is aimed to reduce the solvent consumption and extraction time by employing new green extraction methods which are developed as alternatives to conventional methods. This article reviews the most commonly employed green extraction methods (microwave, ultrasound, high pressure, pulsed electric field, ohmic and supercritical fluid extraction) by focusing on the principals, advantages and applications of the new methods.

Anahtar Kelimeler

• Microwave assisted extraction,ultrasound assisted extraction,ohmic assisted extraction,pulsed electric field assisted extraction,high pressure assisted extraction,supercritical fluid extraction

Kaynakça

1. Álvarez-Casas, M., García-Jares, C., Llompart, M., Lores, M. (2014). Effect of experimental parameters in the pressurized solvent extraction of polyphenolic compounds from white grape marc. Food Chem, 157, 524-532.
2. Angersbach, A., Heinz, V., Knorr, D. (2000). Effects of pulsed electric fields on cell membranes in real food systems. Innov Food Sci Emerg Technol, 1(2), 135-149.
3. Azmir, J., Zaidul, I., Rahman, M., Sharif, K., Mohamed, A., Sahena, F., Omar, A. (2013). Techniques for extraction of bioactive compounds from plant materials: a review. J Food Eng 117(4), 426-436.
4. Balaban, M. (1989). Supercritical extraction: Recovering process materials. Agr Eng, 24-25. Barbosa-Cánovas, G.V., Zhang, Q.H. (2001). Pulsed electric fields in food processing: fundamental aspects and applications: CRC Press.
5. Baysal, T., İçier, F., Baysal, A. (2011). Güncel Elektriksel Isıtma Yöntemleri. Sidas Yayınları, İzmir. Bernardo-Gil, M.G., Roque, R., Roseiro, L.B., Duarte, L.C., Gírio, F., Esteves, P. (2011). Supercritical extraction of carob kibbles (Ceratonia siliqua L.). J Supercrit Fluid, 59, 36-42. Bimakr, M., Rahman, R.A., Ganjloo, A., Taip, F.S., Adzahan, N.M., Sarker, M.Z.I. (2016). Characterization of valuable compounds from winter melon (Benincasa hispida (Thunb.) Cogn.) seeds using supercritical carbon dioxide extraction combined with pressure swing technique. Food Bioprocess Technol, 9(3), 396-406.
6. Bozkurt, P.A. (2011). Atık Lastik-Kömür Karışımlarının Piroliz Ve Kritik Üstü Ekstraksiyonla Değerli Ürünlere Dönüştürülmesi (Doktora Tezi), Ankara Üniversitesi, Ankara.
7. Cai, Z., Qu, Z., Lan, Y., Zhao, S., Ma, X., Wan, Q., Li, P. (2016). Conventional, ultrasound-assisted, and accelerated-solvent extractions of anthocyanins from purple sweet potatoes. Food Chem, 197, 266-272.
8. Cannell, R.J.P. 1998. Natural Products Isolation, Humana Press lnc 999 Rtvervtew Drive, Suite 208 Totowa, New Jersey, 475 s.

9. Chen, F., Sun, Y., Zhao, G., Liao, X., Hu, X., Wu, J., Wang, Z. (2007). Optimization of ultrasound-assisted extraction of anthocyanins in red raspberries and identification of anthocyanins in extract using high-performance liquid chromatography–mass spectrometry. Ultrason Sonochem, 14(6), 767-778.
10. Chen, M., Zhao, Y., Yu, S. (2015). Optimisation of ultrasonic-assisted extraction of phenolic compounds, antioxidants, and anthocyanins from sugar beet molasses. Food Chem, 172, 543-550.
11. Cheok, C., Chin, N., Yusof, Y., Talib, R., Law, C. (2013). Optimization of total monomeric anthocyanin (TMA) and total phenolic content (TPC) extractions from mangosteen (Garcinia mangostana Linn.) hull using ultrasonic treatments. Ind Crops Prod, 50, 1-7.
12. Çam, M., Hışıl, Y. (2010). Pressurised water extraction of polyphenols from pomegranate peels. Food Chem, 123(3), 878-885.
13. Çolak, N., Tülek, Y. (2003). Süperkritik Akışkan Ekstraksiyonu. GIDA, 28(3).
14. D’Alessandro, L.G., Dimitrov, K., Vauchel, P., Nikov, I. (2014). Kinetics of ultrasound assisted extraction of anthocyanins from Aronia melanocarpa (black chokeberry) wastes. Chem Eng Res Des, 92(10), 1818-1826.
15. Dahmoune, F., Nayak, B., Moussi, K., Remini, H., Madani, K. (2015). Optimization of microwave-assisted extraction of polyphenols from Myrtus communis L. leaves. Food Chem, 166, 585-595.
16. Donsì, F., Ferrari, G., Pataro, G. (2010). Applications of pulsed electric field treatments for the enhancement of mass transfer from vegetable tissue. Food Eng Rev, 2(2), 109-130.
17. El Darra, N., Grimi, N., Vorobiev, E., Louka, N., Maroun, R. (2013). Extraction of polyphenols from red grape pomace assisted by pulsed ohmic heating. Food Bioproc Technol, 6(5), 1281-1289. Garofulić, I.E., Dragović-Uzelac, V., Jambrak, A.R., Jukić, M. (2013). The effect of microwave assisted extraction on the isolation of anthocyanins and phenolic acids from sour cherry Marasca (Prunus cerasus var. Marasca). J Food Eng, 117(4), 437-442.
18. Gavahian, M., Farahnaky, A., Javidnia, K., Majzoobi, M. (2013). A novel technology for extraction of essential oil from Myrtus communis: Ohmic-assisted hydrodistillation. J Essent Oil Res, 25(4), 257-266.
19. Gavahian, M., Farhoosh, R., Javidnia, K., Shahidi, F., Farahnaky, A. (2015). Effect of applied voltage and frequency on extraction parameters and extracted essential oils from Mentha piperita by ohmic assisted hydrodistillation. Innov Food Sci Emerg Technol, 29, 161-169. Gizir, A.M., Turker, N., Artuvan, E. (2008). Pressurized acidified water extraction of black carrot [Daucus carota ssp. sativus var. atrorubens Alef.] anthocyanins. Eur Food Res Technol, 226(3), 363-370.
20. Grigoras, C.G., Destandau, E., Zubrzycki, S., Elfakir, C. (2012). Sweet cherries anthocyanins: An environmental friendly extraction and purification method. Sep Purif Technol, 100, 51-58.
21. Gupta, A., Naraniwal, M., Kothari, V. (2012). Modern extraction methods for preparation of bioactive plant extracts. Int J Appl N Sci, 1(1), 8-26.
22. Güvenç, A. (1997). Etanolün fermantasyon çözeltisinden süperkritik CO2 ile ekstraksiyonu. . (Doktora tezi), Ankara Üniversitesi, Ankara.
23. Handa, S.S., Khanuja, S.P.S., Longo, G., Rakesh, D.D. 2008. Extraction Technologies for Medicinal and Aromatic Plants, International Centre For Science and High Technology, Trieste, Italy, 266 s.
24. Herrero, M., Mendiola, J.A., Cifuentes, A., Ibáñez, E. (2010). Supercritical fluid extraction: Recent advances and applications. J Chromatogr A 1217(16), 2495-2511.
25. Herzi, N., Bouajila, J., Camy, S., Romdhane, M., Condoret, J.S. (2013). Comparison of different methods for extraction from Tetraclinis articulata: Yield, chemical composition and antioxidant activity. Food Chem, 141(4), 3537-3545.
26. Hosseini, S.S., Khodaiyan, F., Yarmand, M.S. (2016). Optimization of microwave assisted extraction of pectin from sour orange peel and its physicochemical properties. Carbohydr Polym 140, 59-65.
27. Ivanovic, J., Tadic, V., Dimitrijevic, S., Stamenic, M., Petrovic, S., Zizovic, I. (2014). Antioxidant properties of the anthocyanin-containing ultrasonic extract from blackberry cultivar “Čačanska Bestrna”. Ind Crops Prod, 53, 274-281.
28. Kala H. K., Metha R., Sen K. K., Tandey R., Mandal V. (2017). Strategizing method optimization of microwaveassisted extraction of plant phenolics by developing standard working principles for universal robust optimization. Analytical Methods, 9, 2089-2103.
29. Kaufmann, B., Christen, P. (2002). Recent extraction techniques for natural products: microwave-assisted extraction and pressurised solvent extraction. Phytochem Anal 13(2), 105-113.
30. Kayahan M, Tekin A. (2006). Zeytinyağı Üretim Teknolojisi. TMMOB Gıda Mühendisleri Odası, Kitaplar Serisi.15 198.s Ankara.
31. Kayan, B. (2009). Taxus baccata l’nin farklı ekstraksiyon yöntemleri ile ekstraksiyonu ve ekstraksiyon verimlerinin karşılaştırılması. (Doktora tezi), Mersin Üniversitesi.
32. Kim, J.W., Nagaoka, T., Ishida, Y., Hasegawa, T., Kitagawa, K., Lee, S.C. (2009). Subcritical water extraction of nutraceutical compounds from citrus pomaces. Separ Sci Technol, 44(11), 2598-2608.
33. Lakkakula, N.R., Lima, M., Walker, T. (2004). Rice bran stabilization and rice bran oil extraction using ohmic heating. Bioresource Technol, 92(2), 157-161.
34. Lamanauskas, N., Bobinaitė, R., Satkauskas, S., Viškelis, P., Pataro, G., Ferrari, G. (2015). Pulsed electric field-assisted juice extraction of frozen/thawed blueberries. Zemdirbyste-Agri, 102(1), 59-66.
35. Lebovka, N., Vorobiev, E., Chemat, F. (2011). Enhancing extraction processes in the food industry: CRC Press.
36. Liazid, A., Guerrero, R., Cantos, E., Palma, M., Barroso, C. (2011). Microwave assisted extraction of anthocyanins from grape skins. Food Chem, 124(3), 1238-1243.
37. Loeffler, M.J. (2006). Generation and application of high intensity pulsed electric fields Pulsed Electric Fields Technology for the Food Industry (pp. 27-72): Springer
38. Loginova, K., Lebovka, N., Vorobiev, E. (2011). Pulsed electric field assisted aqueous extraction of colorants from red beet. J Food Eng, 106(2), 127-133.
39. Loypimai, P., Moongngarm, A., Chottanom, P., Moontree, T. (2015). Ohmic heating-assisted extraction of anthocyanins from black rice bran to prepare a natural food colourant. Innov Food Sci Emerg Technol, 27, 102-110.
40. Luque de Castro, M.D., Priego-Capote, F. (2010). Soxhlet extraction: Past and present panacea. Journal of Chromatography A, 1217, 2383-2389.
41. Martın-Belloso, O., Soliva-Fortuny, R. (2011). Pulsed electric fields processing basics. In V. M. B.-C.G.H.Q. Zhang, V. Balasubramaniam, C.P. Dunne, D.F. Farkas, J. T. C. Yuan (Ed.), Nonthermal processing technologies for food (pp. 155–175): Blackwell Publishing Ltd.
42. Mohamed, M.E.A., Eissa, A.H.A. (2012). Structure and Function of Food Engineering. In A.A. Eissa (Ed.), Pulsed Electric Fields for Food Processing Technology (pp. 275-306 )
43. Nakamura, K., Chi, Y.M., Yamada, Y. (1986). Lipase activity and stability in supercritical carbon dioxide. Chem Eng Commun, 45, 207-212. Ong, E.S., Heng, M.Y., Tan, S.N., Hong Yong, J.W., Koh, H., Teo, C.C., Hew, C.S. (2007). Determination of gastrodin and vanillyl alcohol in Gastrodia elata Blume by pressurized liquid extraction at room temperature. J Sep Sci, 30(13), 2130-2137. doi: 10.1002/jssc.200700002
44. Ortiz, R.W.P., Benincá, C., Zanoelo, E.F. (2015). Cyclically pressurized extraction of solutes from ground coffee: Kinetic experiments and modeling. Sep Purif Technol, 141, 256-262. Paes, J., Dotta, R., Barbero, G.F., Martínez, J. (2014). Extraction of phenolic compounds and anthocyanins from blueberry (Vaccinium myrtillus L.) residues using supercritical CO2 and pressurized liquids. J Supercrit Fluid, 95, 8-16.
45. Parniakov, O., Lebovka, N., Van Hecke, E., Vorobiev, E. (2014). Pulsed electric field assisted pressure extraction and solvent extraction from mushroom (Agaricus bisporus). Food Bioprocess Technol, 7(1), 174-183.
46. Petersson, E.V., Liu, J., Sjöberg, P.J., Danielsson, R., Turner, C. (2010). Pressurized hot water extraction of anthocyanins from red onion: A study on extraction and degradation rates. Analytica chimica acta, 663(1), 27-32.
47. Puértolas, E., Cregenzán, O., Luengo, E., Álvarez, I., Raso, J. (2013). Pulsed-electric-field-assisted extraction of anthocyanins from purple-fleshed potato. Food Chem, 136(3), 1330-1336.
48. Ramaswamy, H.S., Marcotte, M., Sastry, S., Abdelrahim, K. (2014). Ohmic heating in food processing: CRC press.
49. Rodriguez, J., Melo, E., Mulet, A., Bon, J. (2013). Optimization of the antioxidant capacity of thyme (Thymus vulgaris L.) extracts: Management of the convective drying process assisted by power ultrasound. J Food Eng, 119(4), 793-799.
50. Ruiz-Aceituno, L., García-Sarrió, M.J., Alonso-Rodriguez, B., Ramos, L., Sanz, M.L. (2016). Extraction of bioactive carbohydrates from artichoke (Cynara scolymus L.) external bracts using microwave assisted extraction and pressurized liquid extraction. Food Chem, 196, 1156-1162.
51. Setyaningsih, W., Saputro, I., Palma, M., Barroso, C. (2015). Optimisation and validation of the microwave-assisted extraction of phenolic compounds from rice grains. Food Chem, 169, 141-149.
52. Strati, I.F., Gogou, E., Oreopoulou, V. (2015). Enzyme and high pressure assisted extraction of carotenoids from tomato waste. Food Bioprod Process, 94, 668-674.
53. Sumnu, G. (2001). A review on microwave baking of foods. Int J Food Sci Technol, 36(2), 117-127.
54. Švarc-Gajić, J., Stojanović, Z., Carretero, A.S., Román, D.A., Borrás, I., Vasiljević, I. (2013). Development of a microwave-assisted extraction for the analysis of phenolic compounds from Rosmarinus officinalis. J Food Eng, 119(3), 525-532.
55. Tao, Y., Wu, D., Zhang, Q.A., Sun, D.W. (2014). Ultrasound-assisted extraction of phenolics from wine lees: Modeling, optimization and stability of extracts during storage. Ultrason Sonochem, 21(2), 706-715.
56. Tchabo, W., Ma, Y., Engmann, F.N., Zhang, H. (2015). Ultrasound-assisted enzymatic extraction (UAEE) of phytochemical compounds from mulberry (Morus nigra) must and optimization study using response surface methodology. Ind Crop Prod, 63, 214-225.
57. Teh, S.S., Niven, B.E., Bekhit, A.E.D.A., Carne, A., Birch, E.J. (2015). Microwave and pulsed electric field assisted extractions of polyphenols from defatted canola seed cake. Int J Food Sci Technol, 50(5), 1109-1115.
58. Tekin, K., Akalın, M.K., Şeker, M.G. (2015). Ultrasound bath-assisted extraction of essential oils from clove using central composite design. Ind Crops Prod, 77, 954-960.
59. Teo, C.C., Tan, S.N., Yong, J.W.H., Hew, C.S., Ong, E.S. (2010). Pressurized hot water extraction (PHWE). J Chromatogr A 1217(16), 2484-2494.
60. Thirugnanasambandham, K., Sivakumar, V., Maran, J.P. (2015). Microwave-assisted extraction of polysaccharides from mulberry leaves. Int J Biol Macromol, 72, 1-5.
61. Truong, V.D., Hu, Z., Thompson, R., Yencho, G.C., Pecota, K. (2012). Pressurized liquid extraction and quantification of anthocyanins in purple-fleshed sweet potato genotypes. J Food Comp Anal, 26(1), 96-103.
62. Vergara-Salinas, J., Vergara, M., Altamirano, C., Gonzalez, Á., Pérez-Correa, J. (2015). Characterization of pressurized hot water extracts of grape pomace: chemical and biological antioxidant activity. Food Chem, 171, 62-69.
63. Wan, H., Wong, M. (1996). Minimization of solvent consumption in pesticide residue analysis. J Chromatogr A 754(1), 43-47.
64. Xi, J., He, L., Yan, L. (2015). Kinetic modeling of pressure-assisted solvent extraction of polyphenols from green tea in comparison with the conventional extraction. Food Chem, 166, 287-291.
65. Zaghdoudi, K., Framboisier, X., Frochot, C., Vanderesse, R., Barth, D., Kalthoum-Cherif, J., Guiavarch, Y. (2016). Response surface methodology applied to Supercritical Fluid Extraction (SFE) of carotenoids from Persimmon (Diospyros kaki L.). Food Chem, 208, 209-219.
66. Zheng, X., Xu, X., Liu, C., Sun, Y., Lin, Z., Liu, H. (2013). Extraction characteristics and optimal parameters of anthocyanin from blueberry powder under microwave-assisted extraction conditions. Sep Purif Technol, 104, 17-25.