Yıl 2021, Cilt 14 , Sayı 1, Sayfalar 125 - 129 2021-01-04

Trizomi 13 ve 18 ile ilişkili prenatal sonografik bulgular; tek bir merkezde prenatal tanı konmuş olguların sunumu
Prenatal sonographic findings associated with trisomy 13 and 18; report of prenatally diagnosed cases in a single center

Emre EKMEKCİ [1] , Özlem ÖZ [2] , Ebru TUNÇEZ [3] , Fedi ERCAN [4] , Emine DEMİR [5]


Amaç: Bu retrospektif çalışmada trizomi 13 ve 18 olan fetüslerin prenatal sonografik bulgularını değerlendirmeyi amaçladık. Gereç ve Yöntem: Doğum öncesi 13 ve 18 trizomi tanısı konan fetusların sonografik bulguları, tek bir tersiyer perinatal merkezde iki yıllık dönemde retrospektif olarak incelendi. Her bir anöploidi için en yaygın bulgular tanımlandı. Bulgular: İki yıl boyunca toplam 13 olguya trizomi 13 veya 18 tanısı konuldu, bunlardan üçü trizomi 13 ve 10'u trizomi 18 idi. Trizomi 13 ile ilişkili majör sonografik anormallik holoprosensefali iken kardiyak anormallikler trizomi 18 için önde gelen bulgudur. Sonuç: Trizomi 13 ve 18, sonografik inceleme ile saptanabilecek majör prenatal sonografik bulgulara sahiptir. Fetal kardiyak ve santral sinir sistemi anormallikleri trizomi 13 ve 18 ile ilişkili başlıca başlıca bulgulardır.
Purpose: In this retrospective study, we aimed to evaluate the prenatal sonographic findings of the fetuses with trisomy 13 and 18. Materials and Methods: The sonographic findings of fetuses which were prenatally diagnosed as trisomy 13 and 18 were retrospectively reviewed in two years’ period at a single tertiary perinatal center. The most common findings for each aneuploidy were described. Results: Total 13 cases were diagnosed as trisomy 13 or 18 during two years’ period of which three cases were trisomy 13 and 10 cases were trisomy 18. Major sonographic abnormality associated with trisomy 13 was holoprosencephaly while cardiac abnormalities were the leading finding for trisomy 18. Conclusion: Trisomy 13 and 18 have major prenatal sonographic findings that may be detected with a targeted sonographic examination. Fetal cardiac and central nervous system abnormalities are the primary major findings associated with trisomy 13 and 18.
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Birincil Dil en
Konular Kadın Hastalıkları ve Doğum
Yayınlanma Tarihi Ocak 2021
Bölüm Araştırma Makalesi
Yazarlar

Orcid: 0000-0003-2494-3073
Yazar: Emre EKMEKCİ
Kurum: ŞANLIURFA EĞİTİM VE ARAŞTIRMA HASTANESİ
Ülke: Turkey


Orcid: 0000-0002-5533-6025
Yazar: Özlem ÖZ
Kurum: HARRAN ÜNİVERSİTESİ, TIP FAKÜLTESİ
Ülke: Turkey


Orcid: 0000-0002-0258-7779
Yazar: Ebru TUNÇEZ
Kurum: Ankara Şehir Hastanesi
Ülke: Turkey


Orcid: 0000-0003-2175-5405
Yazar: Fedi ERCAN
Kurum: ŞANLIURFA EĞİTİM VE ARAŞTIRMA HASTANESİ
Ülke: Turkey


Orcid: 0000-0003-3799-3432
Yazar: Emine DEMİR (Sorumlu Yazar)
Kurum: DENİZLİ DEVLET HASTANESİ
Ülke: Turkey


Tarihler

Yayımlanma Tarihi : 4 Ocak 2021

Bibtex @araştırma makalesi { patd757219, journal = {Pamukkale Tıp Dergisi}, issn = {}, eissn = {1308-0865}, address = {Pamukkale Üniversitesi Tıp Fakültesi Eğitim Blokları Kınıklı kampüsü 20070 Kınıklı, Denizli}, publisher = {Pamukkale Üniversitesi}, year = {2021}, volume = {14}, pages = {125 - 129}, doi = {10.31362/patd.757219}, title = {Prenatal sonographic findings associated with trisomy 13 and 18; report of prenatally diagnosed cases in a single center}, key = {cite}, author = {Ekmekci̇, Emre and Öz, Özlem and Tunçez, Ebru and Ercan, Fedi and Demi̇r, Emine} }
APA Ekmekci̇, E , Öz, Ö , Tunçez, E , Ercan, F , Demi̇r, E . (2021). Prenatal sonographic findings associated with trisomy 13 and 18; report of prenatally diagnosed cases in a single center . Pamukkale Tıp Dergisi , 14. Cilt 1. Sayı , 125-129 . DOI: 10.31362/patd.757219
MLA Ekmekci̇, E , Öz, Ö , Tunçez, E , Ercan, F , Demi̇r, E . "Prenatal sonographic findings associated with trisomy 13 and 18; report of prenatally diagnosed cases in a single center" . Pamukkale Tıp Dergisi 14 (2021 ): 125-129 <https://dergipark.org.tr/tr/pub/patd/issue/56734/757219>
Chicago Ekmekci̇, E , Öz, Ö , Tunçez, E , Ercan, F , Demi̇r, E . "Prenatal sonographic findings associated with trisomy 13 and 18; report of prenatally diagnosed cases in a single center". Pamukkale Tıp Dergisi 14 (2021 ): 125-129
RIS TY - JOUR T1 - Prenatal sonographic findings associated with trisomy 13 and 18; report of prenatally diagnosed cases in a single center AU - Emre Ekmekci̇ , Özlem Öz , Ebru Tunçez , Fedi Ercan , Emine Demi̇r Y1 - 2021 PY - 2021 N1 - doi: 10.31362/patd.757219 DO - 10.31362/patd.757219 T2 - Pamukkale Tıp Dergisi JF - Journal JO - JOR SP - 125 EP - 129 VL - 14 IS - 1 SN - -1308-0865 M3 - doi: 10.31362/patd.757219 UR - https://doi.org/10.31362/patd.757219 Y2 - 2020 ER -
EndNote %0 Pamukkale Tıp Dergisi Prenatal sonographic findings associated with trisomy 13 and 18; report of prenatally diagnosed cases in a single center %A Emre Ekmekci̇ , Özlem Öz , Ebru Tunçez , Fedi Ercan , Emine Demi̇r %T Prenatal sonographic findings associated with trisomy 13 and 18; report of prenatally diagnosed cases in a single center %D 2021 %J Pamukkale Tıp Dergisi %P -1308-0865 %V 14 %N 1 %R doi: 10.31362/patd.757219 %U 10.31362/patd.757219
ISNAD Ekmekci̇, Emre , Öz, Özlem , Tunçez, Ebru , Ercan, Fedi , Demi̇r, Emine . "Prenatal sonographic findings associated with trisomy 13 and 18; report of prenatally diagnosed cases in a single center". Pamukkale Tıp Dergisi 14 / 1 (Ocak 2021): 125-129 . https://doi.org/10.31362/patd.757219
AMA Ekmekci̇ E , Öz Ö , Tunçez E , Ercan F , Demi̇r E . Prenatal sonographic findings associated with trisomy 13 and 18; report of prenatally diagnosed cases in a single center. Pamukkale Tıp Dergisi. 2021; 14(1): 125-129.
Vancouver Ekmekci̇ E , Öz Ö , Tunçez E , Ercan F , Demi̇r E . Prenatal sonographic findings associated with trisomy 13 and 18; report of prenatally diagnosed cases in a single center. Pamukkale Tıp Dergisi. 2021; 14(1): 125-129.
IEEE E. Ekmekci̇ , Ö. Öz , E. Tunçez , F. Ercan ve E. Demi̇r , "Prenatal sonographic findings associated with trisomy 13 and 18; report of prenatally diagnosed cases in a single center", Pamukkale Tıp Dergisi, c. 14, sayı. 1, ss. 125-129, Oca. 2021, doi:10.31362/patd.757219