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Hemoptizi olan ve hemoptizi olmayan hastaların cerrahi tedavi sonuçları

Yıl 2021, Cilt 14, Sayı 4, 892 - 898, 01.10.2021
https://doi.org/10.31362/patd.864790

Öz

Amaç: Hemoptizi hastalarında uygulanan cerrahi girişimlerin artmış komplikasyon riski cerrahlar arasında yaygın bir endişedir. Bu nedenle burada hemoptizi olan tüberküloz hastalarının cerrahi sonuçlarını araştırdık.
Gereç ve yöntem: 1985-2018 yılları arasında cerrahi olarak tüberküloz tanısı alan hastalar retrospektif olarak incelendi. Hastalar iki gruba ayrıldı; hemoptizi olmayanlar (Grup 1) ve hemoptizi olanlar (Grup 2). Analiz yaş, cinsiyet, semptomlar, komorbiditeler, Pozitron Emisyon Tomografisi-Bilgisayarlı Tomografi (PET-CT) bulguları, cerrahi müdahaleler, perioperatif komplikasyonlar, hastanede kalış süreleri, hemoptizi nüksü ve Grup 1 ve 2'nin karşılaştırmasını içeriyordu.
Bulgular: Cerrahi olarak teşhis edilen akciğer tüberkülozu olan 541 hasta incelendi. Grup 1'de 448 hasta, Grup 2'de 93 hasta vardı. Grup 2'deki hastalar Grup 1'deki hastalara göre anlamlı olarak daha gençti (Grup 1 ortalama yaş 57,8±6,2, Grup 2 ortalama yaş 31,2±5,3, p<0,01). Her iki grupta da en sık komorbidite maligniteydi. Grup 2'de kavitasyon daha sıktı (Grup 1 92 (%20,5), Grup 2 79 (%84,9), p<0,01). Postoperatif komplikasyonlar ve hastanede kalış süresi her iki grupta benzerdi ve Grup 2'de hemoptizi rekürrensi yoktu. Grup 1'de perioperatif ölüm görülmezken Grup 2'de 3 (%3) hasta öldü.
Sonuç: Hemoptizi tanısı veya tedavisi için yapılan cerrahi girişim sonrası tüberküloz tanısı alan hastaların cerrahi morbidite ve mortalitesi, hemoptizi olmayan hastalardan anlamlı olarak farklı değildi.

Kaynakça

  • 1. Albay A, Güney M, Tekin K, Kısa Ö, Sığ A. Pulmoner ve ekstrapulmoner örneklerde tüberkülozun erken tanısı ve rifampisin direncinin tespiti için geneXpert MTB/RIF testinin değerlendirilmesi. Cukurova Medical Journal 2016;41:548-53
  • 2. Furin J, Cox H, Pai M. Tuberculosis. Lancet. 2019;393:1642–56
  • 3. Zhang Y, Chen C, Jiang GN. Surgery of massive hemoptysis in pulmonary tuberculosis: immediate and long-term outcomes. J ThoracCardiovasc Surg. 2014;148:651-6.
  • 4. Erdogan A, Yegin A, Gürses G, Demircan A. Surgical management of tuberculosis-related hemoptysis. Ann Thorac Surg. 2005;79:299-302.
  • 5. Cortés-Julián G, Valencia LC, Ríos-Pascual S, de la Rosa-Abarroa MA, Guzmán-de Alba E. Complications of surgery for infectious lung cavities. Asian CardiovascThorac Ann. 2018;26:120-6.
  • 6. Halezeroğlu S, Okur E. Thoracic surgery for hemoptysis in the context of tuberculosis: what is the best management approach? J Thorac Dis. 2014;6:182-5.
  • 7. Evman S, Baysungur V, Alpay L, et al. Management and Surgical Outcomes of Concurrent Tuberculosis and Lung Cancer. ThoracCardiovasc Surg. 2017;65:542-5.
  • 8. Reid MJA, Arinaminpathy N, Bloom A, Bloom BR, Boehme C, Chaisson R, et al. Building a tuberculosis-free world: The Lancet Commission on tuberculosis. Lancet. 2019;393(10178):1331-84.
  • 9. Hilderbrandt J.W., Tarver R.D., Conces D.J., Jr., Broderick L.S., Patel N.H. Diagnostic case study: Rasmussen aneurysm. SeminRespir Infect. 1998;13:160–162.
  • 10. Garay Stuart M. Pulmonary tuberculosis. In: N Rom William, Garay Stuart M., editors. Tuberculosis. second ed. Lippincott Williams & Wilkins; Philadelphia: 2004. p. 367.
  • 11. Echazarreta A, Zerbini E, De Sandro J, et al. Biomedica. Tuberculosis and comorbidities in urban areas in Argentina. A gender and age perspective. Biomedica. 2018;15;38:180-8.
  • 12. Dewan RK, PezzellaAT. Surgical aspects of pulmonary tuberculosis: an update. Asian Cardiovasc Thor Ann. 2016;24: 835-46.
  • 13. Subotic D, Yablonskiy P, Sulis G, et al. Surgery and pleuro-pulmonary tuberculosis: a scientific literature review. J Thorac Dis. 2016;8: 474-85.
  • 14. Mirsadraee M, Shafahie A, Reza Khakzad M, Sankian M. Value of the polymerase chain reaction method for detecting tuberculosis in the bronchial tissue involved by anthracosis. J BronchologyIntervPulmonol. 2014;21:131-4.
  • 15. Lowe VJ, Fletcher JW, Gobar L, et al. Prospective investigation of positron emission tomography in lung nodules. J ClinOncol.1998;16:1075-1084.
  • 16. Hashimoto Y, Tsujikawa T, Kondo C, et al. Accuracy of PET for diagnosis of solid pulmonary lesions with 18F-FDG uptake below thestandardized uptake value of 2.5. J Nucl Med. 2006;47:426-431.
  • 17. Du Toit R, Shaw JA, Irusen EM, Von Groote-Bidlingmaier F, Warwick JM, Koegelenberg CFN. The diagnostic accuracy of integrated positron emission tomography/computed tomography in the evaluation of pulmonary mass lesions in a tuberculosis-endemicarea. S Afr Med. 2015;105:1049-1052.
  • 18. Sathekge MM, Maes A, Pottel H, Stoltz A, Van de Wiele C. Dual time-point FDG PET/CT for differentiating benign from malignant solitary pulmonary nodules in a TB endemic area. S Afr Med J.2010;100:598-601.
  • 19. Marfina GY, Vladimirov KB, Avetisian AO, et al. Bilateral cavitary multidrug- or extensively drug-resistanttuberculosis: role of surgery. European Journal of Cardio-Thoracic Surgery 53 2018;4:618–624.
  • 20. Yun JS, Song SY, Na KJ, et al. Surgery for hemoptysis in patients with benign lung disease. J Thorac Dis. 2018;10:3532-8.

Surgical management outcomes of tuberculosis with hemoptysis and without hemoptysis

Yıl 2021, Cilt 14, Sayı 4, 892 - 898, 01.10.2021
https://doi.org/10.31362/patd.864790

Öz

Objective: Increased complication risk of surgical interventions performed in patients with hemoptysis is a common concern among surgeons. Therefore, here, we investigated the surgical outcomes of tuberculosis patients with hemoptysis.
Materials and methods: Patients, between 1985 and 2018, diagnosed with tuberculosis surgically, were analyzed retrospectively. The patients were divided into two groups; those without hemoptysis (Group 1) and those with hemoptysis (Group 2). The analysis included age, gender, symptoms, comorbidities, Positron Emission Tomography-Computed Tomography (PET-CT) findings, surgical interventions, perioperative complications, lengths of hospital stay, recurrence of hemoptysis, and comparison of Group 1 and 2.
Results: 541 patients with pulmonary tuberculosis diagnosed surgically were analyzed. 448 patients were in Group 1 and 93 patients were in Group 2. The patients in Group 2 were significantly younger than the patients in Group 1 (Group 1 mean age 57.8±6.2, Group 2 mean age 31.2±5.3, p<0.01). The most frequent comorbidity was malignancy in both groups. Cavitation was more common in Group 2 (Group 1 92 (20.5%), Group 2 79 (84.9%), p<0.01). Postoperative complications and hospital stay length were similar in both groups and there was no hemoptysis recurrence in Group 2. There was no perioperative death in Group 1 while 3 (3%) patients died in Group 2.
Conclusion: The surgical morbidity and mortality of patients diagnosed with tuberculosis after the surgical intervention performed for the diagnosis or treatment of the hemoptysis were not significantly different from those of the patients without hemoptysis

Kaynakça

  • 1. Albay A, Güney M, Tekin K, Kısa Ö, Sığ A. Pulmoner ve ekstrapulmoner örneklerde tüberkülozun erken tanısı ve rifampisin direncinin tespiti için geneXpert MTB/RIF testinin değerlendirilmesi. Cukurova Medical Journal 2016;41:548-53
  • 2. Furin J, Cox H, Pai M. Tuberculosis. Lancet. 2019;393:1642–56
  • 3. Zhang Y, Chen C, Jiang GN. Surgery of massive hemoptysis in pulmonary tuberculosis: immediate and long-term outcomes. J ThoracCardiovasc Surg. 2014;148:651-6.
  • 4. Erdogan A, Yegin A, Gürses G, Demircan A. Surgical management of tuberculosis-related hemoptysis. Ann Thorac Surg. 2005;79:299-302.
  • 5. Cortés-Julián G, Valencia LC, Ríos-Pascual S, de la Rosa-Abarroa MA, Guzmán-de Alba E. Complications of surgery for infectious lung cavities. Asian CardiovascThorac Ann. 2018;26:120-6.
  • 6. Halezeroğlu S, Okur E. Thoracic surgery for hemoptysis in the context of tuberculosis: what is the best management approach? J Thorac Dis. 2014;6:182-5.
  • 7. Evman S, Baysungur V, Alpay L, et al. Management and Surgical Outcomes of Concurrent Tuberculosis and Lung Cancer. ThoracCardiovasc Surg. 2017;65:542-5.
  • 8. Reid MJA, Arinaminpathy N, Bloom A, Bloom BR, Boehme C, Chaisson R, et al. Building a tuberculosis-free world: The Lancet Commission on tuberculosis. Lancet. 2019;393(10178):1331-84.
  • 9. Hilderbrandt J.W., Tarver R.D., Conces D.J., Jr., Broderick L.S., Patel N.H. Diagnostic case study: Rasmussen aneurysm. SeminRespir Infect. 1998;13:160–162.
  • 10. Garay Stuart M. Pulmonary tuberculosis. In: N Rom William, Garay Stuart M., editors. Tuberculosis. second ed. Lippincott Williams & Wilkins; Philadelphia: 2004. p. 367.
  • 11. Echazarreta A, Zerbini E, De Sandro J, et al. Biomedica. Tuberculosis and comorbidities in urban areas in Argentina. A gender and age perspective. Biomedica. 2018;15;38:180-8.
  • 12. Dewan RK, PezzellaAT. Surgical aspects of pulmonary tuberculosis: an update. Asian Cardiovasc Thor Ann. 2016;24: 835-46.
  • 13. Subotic D, Yablonskiy P, Sulis G, et al. Surgery and pleuro-pulmonary tuberculosis: a scientific literature review. J Thorac Dis. 2016;8: 474-85.
  • 14. Mirsadraee M, Shafahie A, Reza Khakzad M, Sankian M. Value of the polymerase chain reaction method for detecting tuberculosis in the bronchial tissue involved by anthracosis. J BronchologyIntervPulmonol. 2014;21:131-4.
  • 15. Lowe VJ, Fletcher JW, Gobar L, et al. Prospective investigation of positron emission tomography in lung nodules. J ClinOncol.1998;16:1075-1084.
  • 16. Hashimoto Y, Tsujikawa T, Kondo C, et al. Accuracy of PET for diagnosis of solid pulmonary lesions with 18F-FDG uptake below thestandardized uptake value of 2.5. J Nucl Med. 2006;47:426-431.
  • 17. Du Toit R, Shaw JA, Irusen EM, Von Groote-Bidlingmaier F, Warwick JM, Koegelenberg CFN. The diagnostic accuracy of integrated positron emission tomography/computed tomography in the evaluation of pulmonary mass lesions in a tuberculosis-endemicarea. S Afr Med. 2015;105:1049-1052.
  • 18. Sathekge MM, Maes A, Pottel H, Stoltz A, Van de Wiele C. Dual time-point FDG PET/CT for differentiating benign from malignant solitary pulmonary nodules in a TB endemic area. S Afr Med J.2010;100:598-601.
  • 19. Marfina GY, Vladimirov KB, Avetisian AO, et al. Bilateral cavitary multidrug- or extensively drug-resistanttuberculosis: role of surgery. European Journal of Cardio-Thoracic Surgery 53 2018;4:618–624.
  • 20. Yun JS, Song SY, Na KJ, et al. Surgery for hemoptysis in patients with benign lung disease. J Thorac Dis. 2018;10:3532-8.

Ayrıntılar

Birincil Dil İngilizce
Konular Cerrahi
Yayınlanma Tarihi Ekim 2021
Bölüm Araştırma Makalesi
Yazarlar

Hakan KESKİN (Sorumlu Yazar)
AKDENIZ UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF THORACIC SURGERY
0000-0002-5736-5954
Türkiye


Hulya DİROL
AKDENIZ UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF THORACIC DISEASES
0000-0002-7712-6467
Türkiye


Makbule ERGİN
AKDENIZ UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF THORACIC SURGERY
0000-0002-4373-0009
Türkiye

Yayımlanma Tarihi 1 Ekim 2021
Kabul Tarihi 3 Mayıs 2021
Yayınlandığı Sayı Yıl 2021, Cilt 14, Sayı 4

Kaynak Göster

Bibtex @araştırma makalesi { patd864790, journal = {Pamukkale Tıp Dergisi}, issn = {}, eissn = {1308-0865}, address = {Pamukkale Üniversitesi Tıp Fakültesi Eğitim Blokları Kınıklı kampüsü 20070 Kınıklı, Denizli}, publisher = {Pamukkale Üniversitesi}, year = {2021}, volume = {14}, pages = {892 - 898}, doi = {10.31362/patd.864790}, title = {Surgical management outcomes of tuberculosis with hemoptysis and without hemoptysis}, key = {cite}, author = {Keskin, Hakan and Dirol, Hulya and Ergin, Makbule} }
APA Keskin, H. , Dirol, H. & Ergin, M. (2021). Surgical management outcomes of tuberculosis with hemoptysis and without hemoptysis . Pamukkale Tıp Dergisi , 14 (4) , 892-898 . DOI: 10.31362/patd.864790
MLA Keskin, H. , Dirol, H. , Ergin, M. "Surgical management outcomes of tuberculosis with hemoptysis and without hemoptysis" . Pamukkale Tıp Dergisi 14 (2021 ): 892-898 <https://dergipark.org.tr/tr/pub/patd/issue/63191/864790>
Chicago Keskin, H. , Dirol, H. , Ergin, M. "Surgical management outcomes of tuberculosis with hemoptysis and without hemoptysis". Pamukkale Tıp Dergisi 14 (2021 ): 892-898
RIS TY - JOUR T1 - Surgical management outcomes of tuberculosis with hemoptysis and without hemoptysis AU - Hakan Keskin , Hulya Dirol , Makbule Ergin Y1 - 2021 PY - 2021 N1 - doi: 10.31362/patd.864790 DO - 10.31362/patd.864790 T2 - Pamukkale Tıp Dergisi JF - Journal JO - JOR SP - 892 EP - 898 VL - 14 IS - 4 SN - -1308-0865 M3 - doi: 10.31362/patd.864790 UR - https://doi.org/10.31362/patd.864790 Y2 - 2021 ER -
EndNote %0 Pamukkale Tıp Dergisi Surgical management outcomes of tuberculosis with hemoptysis and without hemoptysis %A Hakan Keskin , Hulya Dirol , Makbule Ergin %T Surgical management outcomes of tuberculosis with hemoptysis and without hemoptysis %D 2021 %J Pamukkale Tıp Dergisi %P -1308-0865 %V 14 %N 4 %R doi: 10.31362/patd.864790 %U 10.31362/patd.864790
ISNAD Keskin, Hakan , Dirol, Hulya , Ergin, Makbule . "Surgical management outcomes of tuberculosis with hemoptysis and without hemoptysis". Pamukkale Tıp Dergisi 14 / 4 (Ekim 2021): 892-898 . https://doi.org/10.31362/patd.864790
AMA Keskin H. , Dirol H. , Ergin M. Surgical management outcomes of tuberculosis with hemoptysis and without hemoptysis. Pam Tıp Derg. 2021; 14(4): 892-898.
Vancouver Keskin H. , Dirol H. , Ergin M. Surgical management outcomes of tuberculosis with hemoptysis and without hemoptysis. Pamukkale Tıp Dergisi. 2021; 14(4): 892-898.
IEEE H. Keskin , H. Dirol ve M. Ergin , "Surgical management outcomes of tuberculosis with hemoptysis and without hemoptysis", Pamukkale Tıp Dergisi, c. 14, sayı. 4, ss. 892-898, Eki. 2021, doi:10.31362/patd.864790