Myocardial performance index is associated with Systematic Coronary Risk Estimation (SCORE) system in chronic coronary syndrome

Yıl 2021, Cilt: 14 Sayı: 4, 818 - 827, 01.10.2021

Hazar Harbalıoğlu , Omer Genc , Abdullah Yıldırım

https://doi.org/10.31362/patd.910961

Öz

Objective: The Systematic Coronary Risk Estimation (SCORE) system is used to determine 10-year cardiovascular risk. Myocardial performance index (MPI), a well-accepted echocardiographic parameter, is used to provide an information about global function of the ventricle. We aimed to investigate the relationship between MPI and SCORE.
Methods: A total of 168 participants with chronic coronary syndrome (CCS) presented to cardiology outpatient clinic between 1 June and 31 December 2020 were retrospectively enrolled in the study. Cardiovascular risk estimation was calculated by SCORE assessment. The participants were divided into two groups as 46 patients with low cardiovascular risk, and 122 patients with moderate-high-very high risk, according to the SCORE. Laboratory parameters and echocardiography findings of the patients were recorded.
Results: There was no difference in body mass index, office systolic, and diastolic blood pressure between the groups. While blood glucose was 94.5 (83.0-110.3) in the low-risk group, it was 101.0 (90.0-130.5) in the moderate-high risk patient group (p = 0.007). Similarly, Urea, creatinine, lactate dehydrogenase, total cholesterol, NT pro-BNP, and Troponin T in the moderate-high risk group were significantly higher than was the low-risk group. MPI was significantly higher in the moderate-high risk patient group (p <0.001). MPI (OR = 2.358, 95 % CI: 1.033-5.382, p = 0.042), urea (OR = 1.090, 95 % CI: 1.019-1.166, p = 0.012), and glucose (OR = 1.023, 95 % CI: 1.003-1.043, p = 0.025) were independently associated with the moderate-high SCORE.
Conclusion: We found that MPI predicted moderate-high SCORE system. Further studies are warranted to better clarify the association of SCORE with echocardiographic parameters including MPI.

Anahtar Kelimeler

myocardial performance index, Systematic Coronary Risk Estimation (SCORE) system, chronic coronary syndrome, cardiovascular risk

Kronik koroner sendromda miyokardial performans indeks ile Sistematik Koroner Risk Tahmini (SCORE) arasındaki ilişki

Öz

Amaç: Sistematik Koroner Risk Tahmin (SCORE) sistemi, 10 yıllık kardiyovasküler riski belirlemek için kullanılır. Kabul gören bir ekokardiyografik parametre olan miyokardiyal performans indeksi (MPI), ventrikülün global işlevi hakkında bilgi sağlamak için kullanılır. Biz; MPI ve SCORE arasındaki ilişkiyi araştırmayı amaçladık.
Gereç ve Yöntem: 1 Haziran - 31 Aralık 2020 tarihleri arasında kardiyoloji polikliniğine başvuran kronik koroner sendromlu (KKS) toplam 168 hasta retrospektif olarak çalışmaya alındı. Kardiyovasküler risk tahmini SCORE değerlendirmesi ile hesaplandı. SCORE'a göre hastalar düşük kardiyovasküler riskli 46 hasta ve orta-yüksek-çok yüksek riskli 122 hasta olarak iki gruba ayrıldı. Hastaların laboratuvar parametreleri ve ekokardiyografi bulguları kaydedildi.
Bulgular: Gruplar arasında vücut kitle indeksi, ofis sistolik ve diyastolik kan basıncı açısından fark yoktu. Kan şekeri düşük risk grubunda 94,5 (83,0-110,3) iken, orta-yüksek riskli hasta grubunda 101,0 (90,0-130,5) idi (p = 0,007). Benzer şekilde, orta-yüksek risk grubundaki Üre, kreatinin, laktat dehidrogenaz, total kolesterol, NT pro-BNP ve Troponin T, düşük risk grubuna göre anlamlı olarak daha yüksekti. Orta-yüksek riskli hasta grubunda MPI anlamlı olarak daha yüksekti (p <0.001). MPI (OR = 2,358,% 95 CI: 1,033-5,382, p = 0,042), üre (OR = 1,090,% 95 CI: 1,019-1,166, p = 0,012) ve glikoz (OR = 1,023,% 95 CI: 1,003 -1,043, p = 0,025) bağımsız olarak orta-yüksek SCORE ile ilişkilendirildi.
Sonuç: MPI'nin orta-yüksek SCORE sistemini öngördüğünü bulduk. SCORE ile MPI de dahil olmak üzere ekokardiyografik parametreler arasındaki ilişkiyi daha iyi açıklığa kavuşturmak için ileri çalışmalara ihtiyaç vardır.

Anahtar Kelimeler

Miyokardiyal performans indeks, Sistematik Koroner Risk Tahmin (SCORE) sistemi, kronik koroner sendrom, kardiyovasküler risk

Kaynakça

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