Caryophyllaceae Familyasına Ait Karakteristik Sekonder Metabolitler ve Biyolojik Aktiviteleri

Gamze Erikci; Hatice Çölgeçen; Havva Karahan

doi:10.53433/yyufbed.1688381

EN TR

The Characteristic Secondary Metabolites and Biological Activities of Caryophyllaceae Family

Öz

Various species within the family Caryophyllaceae have been used in traditional medicinal practices by diverse ethnic communities worldwide, particularly in Chinese medicine. The family is notably rich in secondary metabolites-including saponins, steroids, alkaloids, terpenoids, and phenolic compounds-whose positive effects on human health have been widely investigated. These secondary metabolites are bioactive compounds that contribute to ecological balance by enhancing plants’ ability to respond to environmental stresses, and they play a critical role in defence mechanisms against pests, pathogens, and other environmental threats. Owing to their pharmacological potential, such compounds have been utilized in traditional medical systems for centuries and have contributed to the development of novel therapeutic approaches in modern medicine. Studies on the secondary metabolites of Caryophyllaceae species indicate that members of this family exhibit anticancer, antibacterial, antifungal, antiviral, antioxidant, anti-inflammatory, and other therapeutic properties. The aim of this study is to review the ethnobotanical significance of Caryophyllaceae species and to summarize the key secondary metabolites characteristic of the family. This review highlights the medicinal importance of these metabolites and provides a valuable foundation for future research on the Caryophyllaceae family.

Anahtar Kelimeler

Caryophyllaceae, Secondary metabolites, Biological activity

Caryophyllaceae Familyasına Ait Karakteristik Sekonder Metabolitler ve Biyolojik Aktiviteleri

Öz

Caryophyllaceae familyasında bulunan çeşitli türler dünya çapında birçok etnik topluluk tarafından geleneksel tıpta ağırlıklı olarak Çin tıbbında kullanılmaktadır. Caryophyllaceae sekonder metabolitlerce zengin bir familya olup içerdiği saponinler, steroidler, alkaloidler, terpenoidler ve fenolik bileşikler in insan sağlığı üzerindeki olumlu etkileri çeşitli bilim insanları tarafından araştırılmıştır. Sekonder metabolitler, bitkilerin çevresel streslere yanıt verme kabiliyetini artırarak ekosistem dengesinin korunmasına katkıda bulunan; zararlılara, patojenlere ve diğer çevresel tehditlere karşı savunma mekanizmalarında kritik bir rol oynayan biyoaktif bileşiklerdir. Bu bileşikler farmakolojik potansiyeli sayesinde geleneksel tıpta uzun yıllar kullanılmış ve modern tıpta yeni tedavi yöntemlerinin geliştirilmesine olanak tanımıştır. Bu familyanın sekonder metabolitlerinin çalışılması, familyada mevcut bitkilerin antikanser, antibakteriyel, antifungal, antiviral, antioksidan, antiinflamatuar ve terapötik özelliklere sahip olduğunu göstermektedir. Bu çalışma, Caryophyllaceae familyasına ait bitkilerin sekonder metabolitlerinin derlenmesi, bu bileşiklerin fitokimyasal çeşitliliğinin ortaya konması ve literatürde raporlanan farmakolojik, biyolojik ve etnomedikal etkilerini bütüncül bir bakış açısıyla değerlendirmeyi amaçlamıştır. Bu derleme, familyanın sekonder metabolitlerini ve tıbbi özelliklerinin önemine dikkat çekerek Caryophyllaceae familyasında gelecekte yapılacak araştırmalar için değerli bilgiler sağlamaktadır.

Anahtar Kelimeler

Caryophyllaceae, Sekonder metabolit, Biyolojik aktivite

Etik Beyan

Bu çalışmada araştırma ve yayın etiği ilkelerine uyulmuş, verilerde herhangi bir tahrifat yapılmamış ve yararlanılan tüm kaynaklar uygun şekilde atıf yapılarak belirtilmiştir. Bu çalışma kapsamında insan ya da hayvan denekler kullanılmadığından etik kurul onayı gerekmemektedir.

Teşekkür

Bu çalışma, 2025-84906727-05 No’ lu proje ile desteklenmiş olup, katkılarından dolayı ZBEUN Bilimsel Araştırma Projeleri Birimi (B.A.P.)’ne teşekkür ederiz. Bu çalışma, Gamze ERİKCİ'nin Zonguldak Bülent Ecevit Üniversitesi, Fen Bilimleri Enstitüsü'nde Prof.Dr. Hatice ÇÖLGEÇEN danışmanlığında tamamladığı Sabulina mesogıtana subsp. Flaccıda Endemik Türününde Organogenez Ve İnce Yapı başlıklı Yüksek Lisans tezinden üretilmiştir.

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Bitki Bilimi (Diğer)

Bölüm

Derleme

Yazarlar

Gamze Erikci ^*
0009-0008-0188-8941
Türkiye

Hatice Çölgeçen
0000-0001-8246-4279
Türkiye

Havva Karahan
0000-0003-0518-6265
Türkiye

Yayımlanma Tarihi

4 Mayıs 2026

Gönderilme Tarihi

1 Mayıs 2025

Kabul Tarihi

26 Ocak 2026

Yayımlandığı Sayı

Yıl 2026 Cilt: 31

DOI

https://doi.org/10.53433/yyufbed.1688381

IZ

https://izlik.org/JA37TJ92BR

APA

Erikci, G., Çölgeçen, H., & Karahan, H. (2026). Caryophyllaceae Familyasına Ait Karakteristik Sekonder Metabolitler ve Biyolojik Aktiviteleri. Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 31, 309-330. https://doi.org/10.53433/yyufbed.1688381

AMA

1.Erikci G, Çölgeçen H, Karahan H. Caryophyllaceae Familyasına Ait Karakteristik Sekonder Metabolitler ve Biyolojik Aktiviteleri. YYUFBED. 2026;31:309-330. doi:10.53433/yyufbed.1688381

Chicago

Erikci, Gamze, Hatice Çölgeçen, ve Havva Karahan. 2026. “Caryophyllaceae Familyasına Ait Karakteristik Sekonder Metabolitler ve Biyolojik Aktiviteleri”. Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi 31 (Mayıs): 309-30. https://doi.org/10.53433/yyufbed.1688381.

EndNote

Erikci G, Çölgeçen H, Karahan H (01 Mayıs 2026) Caryophyllaceae Familyasına Ait Karakteristik Sekonder Metabolitler ve Biyolojik Aktiviteleri. Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi 31 309–330.

IEEE

[1]G. Erikci, H. Çölgeçen, ve H. Karahan, “Caryophyllaceae Familyasına Ait Karakteristik Sekonder Metabolitler ve Biyolojik Aktiviteleri”, YYUFBED, c. 31, ss. 309–330, May. 2026, doi: 10.53433/yyufbed.1688381.

ISNAD

Erikci, Gamze - Çölgeçen, Hatice - Karahan, Havva. “Caryophyllaceae Familyasına Ait Karakteristik Sekonder Metabolitler ve Biyolojik Aktiviteleri”. Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi 31 (01 Mayıs 2026): 309-330. https://doi.org/10.53433/yyufbed.1688381.

JAMA

1.Erikci G, Çölgeçen H, Karahan H. Caryophyllaceae Familyasına Ait Karakteristik Sekonder Metabolitler ve Biyolojik Aktiviteleri. YYUFBED. 2026;31:309–330.

MLA

Erikci, Gamze, vd. “Caryophyllaceae Familyasına Ait Karakteristik Sekonder Metabolitler ve Biyolojik Aktiviteleri”. Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi, c. 31, Mayıs 2026, ss. 309-30, doi:10.53433/yyufbed.1688381.

Vancouver

1.Gamze Erikci, Hatice Çölgeçen, Havva Karahan. Caryophyllaceae Familyasına Ait Karakteristik Sekonder Metabolitler ve Biyolojik Aktiviteleri. YYUFBED. 01 Mayıs 2026;31:309-30. doi:10.53433/yyufbed.1688381

The Characteristic Secondary Metabolites and Biological Activities of Caryophyllaceae Family

Öz

Anahtar Kelimeler

Caryophyllaceae Familyasına Ait Karakteristik Sekonder Metabolitler ve Biyolojik Aktiviteleri

Öz

Anahtar Kelimeler

Etik Beyan

Teşekkür

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

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