Sigara içiminin semen kalitesi üzerine etkisi

Yıl 2002, Cilt: 33 Sayı: 4, 48 - 52, 01.05.2002

Cem Fıçıcıoğlu Belgin Devranoğlu Selçuk Özden Serap Yaltı Birgül Gürbüz Gözde Erkanlı

Öz

Amaç: Sigara içen infertil vakalar ile sigara içmeyen infertil vakaların semen parametrelerinin karşılaştırılması. Metod: En az bir yıldır infertil olan 224 (122 olgu sigara içen, 102 olgu sigara içmeyen) olgu çalışma grubuna dahil edildi. Her olgunun anamnezi alındı, fizik muayenesi yapıldı ve her olgudan yedi günlük aralarla iki kez semen analizi istendi. Semenin fiziksel ve kimyasal özellikleri ile birlikte morfolojik değerlendirmeside yapıldı. Bulgular: Sigara içenlerin ortalama sperm volümü, kontrol grubundan anlamlı ölçüde düşükdü (p

Anahtar Kelimeler

Sigara içme, Semen, Kısırlık, erkek, Araştırma teknikleri

Effect of cigarette smoking on human semen quality

Öz

Objective: Semen parameters of infertile smokers were compared with semen parameters of infertile non-smokers. Materials and Methods: 224 men (122 smokers, 102 non smokers) with infertility for at least one year were evaluated. Evaluation included medical history, physical examination and two semen analyses taken seven days period. Physical, chemical and morphological features of semen was evaluated. Results: Mean semen volume and sperm number of smokers were significantly lower than non-smokers (p0.05). Conclusion: Fertilization capacity of males was not effected by cigarette smoking if the number of sperm and the morphology of sperm are normal enough. If these values are subnormal may be effected by cigarette smoking and may result with male infertility.

Anahtar Kelimeler

Smoking, Semen, Infertility, Male, Investigative Techniques

Kaynakça

• 1. Langgasner, J. Rauchgew wohnheiten der österre- ichischen Bevölkerung. Statistiche Nachrichten 1999;5:319-326
• 2. Shaban FS. Male Factor Infertility.lnfertility and Reproductive Medicine Clinics of North America 1995;6:1:229 3. Kase GN. Male infertility. In: Speroff L, Glass RH, Kase GN eds. Clinical Gynecologic Endocrinology and Infertility. 5th ed. Portland: Williams and Wilkins co, 1994:873-896 4. Godfrey B.Sperm Morphology in Smokers.Lancet 1982,1:948-952 5. Sokal RZ. The diagnosis and treatment of male infertility: Current Opinion in Obst. And Gynecology 1995;7:177-181 6. Lewin A.,Gonem O.,Orvieto R. And Schenker, JG
• Effect of smoking on concentration, motility and zona free hamster test on human sperm. Arch
• Androl 1991;27:51-54
• 7. Sofikitis N, Miyagawa I, Dimitriadis D, Zavos P,Sikka S. andnd Hellstrom W. Effects of smoking on testicular function, semen quality and sperm fertil¬izing capacity. J Urol 1995;154:1030-1034
• 8. Zineman, MJ.,Brown, CC, Selevan, SG. and Clegg, ED. Semen quality and human fertility: a prospective study with healthy couples. J Androl 2000;21:145-153
• 9. Vine, M.F. Smoking and male reproductions review.lntj Androl 1996;19:323-337. : 10. Klaibr, EL., Broverman, DM., Pokoly, TB., Albert AJ., Howard PJ., and Sherer, JF. Interrelationships of cigarette smoking,testicular varicoceles, and seminal fluid indexes. Fertil.Steril 1987;47:481-486
• 11. Saaranen M. Cigarette smoking and semen qual¬ ity in of reproductive age Andrologia 1987;19:670-677 12. Blaired DD, Wilcox AJ. Cigarette smoking asso¬ ciated with delayed conception. JAMA 1985;253:2979-2983 13. Hughes, EG. Cigarette smoking on the out¬ comes of in vitro fertilization: measurement of effect size and levels of action. Fertil steril 1994;62:807-814 14. Klonoff-Cohen H, Natarjan L. Marrs R. Effects of female and male smoking on success rates of IVF and gamete intra Fallopion transfer Human Reproduction 2001; 16: 1382-1390
• 15. Dikshit R, Buch J, Effect of tobacco consumption on semen quality of a population of hypofertile males.Fertil Steril 1987;48:334-336 16. Osser S. Semen quality of smoking and non smoking men in infertile couples in a Swedish popu¬ lation. Acta Obstet Gynecol Scand 1992;71:215-218 17. Chia SE, Ong CN. Effects of cigarette smoking on human semen quality. Arch Androl 1994;33:163-168 18. Kolikauskas V.Cigarette smoking and its possi¬ ble effects on sperm. Fertil Steril 1985;44:526-531 19. Vogt HJ. Sperm quality of healty smokers, ex smokers and never smokers. Fertil Steril 1986;45:106-110 20. Saaranen M. Human seminal plasma codmium :comparison with fertility and smoking habits
• Andrologia 1989;21:140-145 21. Effendy I. Krause W. Environmental risk factors in the history of malepatients of an infertility clin- ic.Andrologia 1987; 19:262-265 22. Dunphy BC, BarratCL. Male cigarette smoking and fecundity in couples attending an infertility clin- ic.Andrologia 1991;23:223-225 23. Rodriguez-Rigau LS. Cigarette smoking and semen quality. Fertil Steril 1982;38:115-116 24. Marshburn PB. Semen quality and association with cöfee drinking, cigarette smoking and ethanol consumption. Fertil Steril 1989;52:162-165 25. Hoidas S. Scoring sperm morphology from fertile and infertile cigarette smokers using the scaning electron microscope and image analysis. Fertil Steril 1985;43:595-598 26. Gerhard I, Frochlich E. Relationship of sperm acrosin activity to semen and clinical parameters in infertile patients. Andrologia 1989;21:146-154 27. Klaiber EL, Broverman DM, Dynamics of estra- diol and testesteron and seminal fluid indexes in smokers and non smokers. Fertil Steril 1988;50:630- 634 28. Klaiber EL, Broverman DM, Dalen SE. Serum estradiol levels in male cigarette smokers. Am J Med 1984;77:858-862 29. Shaarawy M, Mahmoud KZ. Endocrine profile and semen charecteristics in male smokers. Fertil Steril. 1982;38:255-257