Review

Exploring the Anticancer Potential of Monoterpenes: Mechanistic Basis and Synergistic Effects

Number: 2026 July 18, 2026
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Exploring the Anticancer Potential of Monoterpenes: Mechanistic Basis and Synergistic Effects

Abstract

Cancer, marked by uncontrolled cell growth and the ability to spread to other tissues, remains a growing global health challenge. Natural compounds are gaining attention in cancer treatment for their potential to improve therapeutic outcomes and reduce harmful side effects. Recent studies have shown that these compounds can improve treatment outcomes while minimizing side effects. Among these, monoterpenes have shown promising anticancer properties, making them valuable candidates for cancer therapy. Due to their wide range of biological activities and natural abundance, monoterpenes are increasingly being explored as promising agents in cancer treatment. Research has shown that monoterpenes can boost the efficacy of conventional anticancer therapies by modulating key signaling pathways and cellular processes. Although preclinical studies strongly support the potential of monoterpenes in cancer therapy, several challenges limit their clinical application such as toxicity and low bioavailability. Continued research on structural modifications and advanced delivery systems is essential to fully realize their therapeutic potential in clinical settings. This review explores the effects of monoterpenes on cancer cells, their potential in combination therapies, the limitations associated with their clinical use, and future directions for their therapeutic development.

Keywords

natural compounds, monoterpenes, cancer therapy, drug resistance

References

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APA
İpek Baloğlu, K., & Erdoğan, A. (2026). Exploring the Anticancer Potential of Monoterpenes: Mechanistic Basis and Synergistic Effects. Journal of Anatolian Environmental and Animal Sciences, 2026. https://doi.org/10.35229/jaes.1926404
AMA
1.İpek Baloğlu K, Erdoğan A. Exploring the Anticancer Potential of Monoterpenes: Mechanistic Basis and Synergistic Effects. JAES. 2026;(2026). doi:10.35229/jaes.1926404
Chicago
İpek Baloğlu, Kevser, and Ayşe Erdoğan. 2026. “Exploring the Anticancer Potential of Monoterpenes: Mechanistic Basis and Synergistic Effects”. Journal of Anatolian Environmental and Animal Sciences, nos. 2026. https://doi.org/10.35229/jaes.1926404.
EndNote
İpek Baloğlu K, Erdoğan A (July 1, 2026) Exploring the Anticancer Potential of Monoterpenes: Mechanistic Basis and Synergistic Effects. Journal of Anatolian Environmental and Animal Sciences 2026
IEEE
[1]K. İpek Baloğlu and A. Erdoğan, “Exploring the Anticancer Potential of Monoterpenes: Mechanistic Basis and Synergistic Effects”, JAES, no. 2026, July 2026, doi: 10.35229/jaes.1926404.
ISNAD
İpek Baloğlu, Kevser - Erdoğan, Ayşe. “Exploring the Anticancer Potential of Monoterpenes: Mechanistic Basis and Synergistic Effects”. Journal of Anatolian Environmental and Animal Sciences. 2026 (July 1, 2026). https://doi.org/10.35229/jaes.1926404.
JAMA
1.İpek Baloğlu K, Erdoğan A. Exploring the Anticancer Potential of Monoterpenes: Mechanistic Basis and Synergistic Effects. JAES. 2026. doi:10.35229/jaes.1926404.
MLA
İpek Baloğlu, Kevser, and Ayşe Erdoğan. “Exploring the Anticancer Potential of Monoterpenes: Mechanistic Basis and Synergistic Effects”. Journal of Anatolian Environmental and Animal Sciences, no. 2026, July 2026, doi:10.35229/jaes.1926404.
Vancouver
1.Kevser İpek Baloğlu, Ayşe Erdoğan. Exploring the Anticancer Potential of Monoterpenes: Mechanistic Basis and Synergistic Effects. JAES. 2026 Jul. 1;(2026). doi:10.35229/jaes.1926404