Laktoferrinin Biyolojik Aktivitesi

Yıl 2011, Cilt: 9 Sayı: 6, 52 - 63, 01.12.2011

Zeliha Yıldırım Mehmet Tokatlı Nilgün Öncül Metin Yıldırım

Öz

Transferrin protein ailesi içinde yer alan laktoferrin, başta süt olmak üzere birçok sıvıda bulunan demir bağlayan bir glikoproteindir. Laktoferrin antibakteriyal, antifungal, antiviral, antiprotozoal, antioksidant, antikanserojen, kemik sağlığını iyileştirici, bağırsakta demir absorpsiyonunu düzenleyici, antienflamatuar, immünomodulatör gibi birçok biyolojik aktiviteye sahip olduğundan çok fonksiyonlu protein olarak değerlendirilmektedir. Bu derlemede inek sütü laktoferrinin kimyasal ve yapısal özellikleri ile biyolojik aktiviteleri hakkında bilgiler verilmektedir

Anahtar Kelimeler

Süt, Serum proteini, Laktoferrin, Biyolojik aktivite

Biological Activity of Lactoferrin

Öz

Lactoferrin is an iron-binding glycoprotein of the transferrin family and it is mainly found in milk and in most biological fluids. Lactoferrin is a multifunctional protein since it has many biological activities including antibacterial, antifungal, antiviral, antiprotozoal, antioxidant and anticarcinogenic activity, improvement of bone health, regulator of iron absorption in intestine, anti-inflammatory activity, and immunomodulatory. In this review article, we focus on the chemical and structural properties, and biological activities of bovine milk lactoferrin

Anahtar Kelimeler

Milk, Whey protein, Lactoferrin, Biological activities

Kaynakça

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