Diyet İndüklü Obeziteyi Modellemek için Güvenilir Bir Yöntem: Kafeterya Diyeti

Yıl 2023, Cilt: 2 Sayı: 3, 28 - 36, 30.09.2023

Ebru Yazıcı

https://doi.org/10.59518/farabimedj.1210558

Öz

Obezite, hem gelişmiş hem de gelişmekte olan ülkelerde tüm yaş gruplarında görülen, birçok hastalığa neden olan oldukça yaygın metabolik bir hastalıktır. İnsan fizyolojisine ve metabolik özelliklerine benzerlik gösteren kemirgenlerde obezite gibi hastalıklar çeşitli diyetler kullanılarak taklit edilebilmektedir. Diyet indüklü obezite (DİO) modelleri, obezite gibi metabolik hastalıkların araştırılmasında oldukça önemlidir. Buna rağmen hangi DİO modelinin insanlardaki obezite patolojisini en iyi şekilde yansıttığı hala tartışma konusudur. Deney hayvanlarında kullanılan kafeterya diyeti (KD) modeli, batı toplumlarında sıklıkla tüketilen sağlıksız besinlerin bir araya getirilmesiyle oluşturulur. KD modeli, insanlardaki yeme alışkanlıklarını diğer modellere göre daha iyi yansıtır. Bu derlemede, diyet indüklü obezite modelleri arasında obeziteyi diğer modellere göre daha iyi yansıtan KD değerlendirilmiştir.

Anahtar Kelimeler

Kafeterya diyeti, Obezite, Diyet indüklü obezite, yüksek şekerli diyet, yüksek yağlı diyet

New Trend in Diet Induced Obesity Models: Cafeteria Diet

Öz

Obesity is a very common metabolic disease that is seen in all age groups in both developed and developing countries and causes many diseases. Diseases such as obesity in rodents, which are similar to human physiology and metabolic characteristics, can be mimicked by using various diets. Diet-induced obesity (DIO) models are very important in the investigation of metabolic diseases such as obesity. However, it is still a matter of debate which DIO model best reflects the pathology of obesity in humans. The cafeteria (CAF) diet model used in experimental animals is created by combining unhealthy foods that are frequently consumed in Western societies. It is formed by combining a wide variety of foods with high energy value and delicious, such as The CAF diet model better reflects human eating habits than other models. In this review, the CAF diet, which reflects obesity better than other models, was evaluated among diet-induced obesity models.

Anahtar Kelimeler

Cafeteria diet, Obesity, Diet induced obesity, high sugar diet, high fat diet

Kaynakça

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