Araştırma Makalesi
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Tarhun ve Kişniş Tohumunun Uçucu Yağ Bileşenleri

Yıl 2019, Cilt: 2 Sayı: 1, 26 - 33, 01.07.2019

Öz

Araştırmada, Bayburt ilinden temin edilen tarhun
(Artemisia dracunculus) ile Erzurum
ilinden temin edilen kişniş tohumu (Coriandrum
sativum)
örneklerinin su distilasyonu ile uçucu yağları elde edilmiştir.
Elde edilen yağların uçucu yağ bileşenleri gaz kromatografisi/kütle
spektrometrisi(GC/MS) ile belirlenmiştir. Kişniş tohumunda 38, tarhunda ise 48
bileşen tanımlanmıştır.  Kişniş tohumu
uçucu yağının en önemli bileşeni linalool olarak belirlenmiştir. Bunu sırasıyla
γ-terpinen, alfa pinen, geraniol ve D-limonen izlemiştir. Bütanal, pentanal,
hekzanal, 2-hekzanal, heptanal, benzaldehit, kopaen, alfa-fellandren ve 3-karen
ise oldukça düşük miktarlarda belirlenmiştir. Tarhun uçucu yağında major
bileşen olarak estragol  belirlenmiş ve
bunu sırasıyla metil öjenol, elemisin, isoelemisin, β-osimen, terpinen-4-ol ve
D-limonen izlemiştir.

Kaynakça

  • [1] Bayrak, A . (1985). Turunçgil uçucu yağları ve aromalarına etkili bazı bileşenler. Gıda, 10 (1) . Retrieved from http://dergipark.gov.tr/gida/issue/6924/92497.
  • [2] Ríos, J. L. (2016). Essential oils: What they are and how the terms are used and defined. In Essential Oils in Food Preservation, Flavor and Safety (pp. 3-10). Academic Press.
  • [3] Dima, C., & Dima, S. (2015). Essential oils in foods: extraction, stabilization, and toxicity. Current Opinion in Food Science, 5, 29-35.
  • [4] Deans, S. G., & Ritchie, G. (1987). Antibacterial properties of plant essential oils. International journal of food microbiology, 5(2), 165-180.
  • [5] Kalemba, D. A. A. K., & Kunicka, A. (2003). Antibacterial and antifungal properties of essential oils. Current medicinal chemistry, 10(10), 813-829.
  • [6] Soković, M., Glamočlija, J., Marin, P. D., Brkić, D., & van Griensven, L. J. (2010). Antibacterial effects of the essential oils of commonly consumed medicinal herbs using an in vitro model. Molecules, 15(11), 7532-7546.
  • [7] Koch, C., Reichling, J., Schneele, J., & Schnitzler, P. (2008). Inhibitory effect of essential oils against herpes simplex virus type 2. Phytomedicine, 15(1-2), 71-78.
  • [8] Orhan, İ. E., Özçelik, B., Kartal, M., & Kan, Y. (2012). Antimicrobial and antiviral effects of essential oils from selected Umbelliferae and Labiatae plants and individual essential oil components. Turkish Journal of Biology, 36(3), 239-246.
  • [9] Soylu, E. M., Kurt, Ş., & Soylu, S. (2010). In vitro and in vivo antifungal activities of the essential oils of various plants against tomato grey mould disease agent Botrytis cinerea. International Journal of Food Microbiology, 143(3), 183-189.
  • [10] Akgül, A., & Kivanc, M. (1988). Inhibitory effects of selected Turkish spices and oregano components on some foodborne fungi. International Journal of Food Microbiology, 6(3), 263-268.
  • [11] Graßmanna, J., Hippelia, S., Dornischa, K., Rohnerta, U., Beuscherb, N., & Elstnera, E. F. (2000). Antioxidant properties of essential oils. Arzneimittelforschung, 50(02), 135-139.
  • [12] Paranagama, P. A., Abeysekera, K. H. T., Abeywickrama, K., & Nugaliyadde, L. (2003). Fungicidal and anti‐aflatoxigenic effects of the essential oil of Cymbopogon citratus (DC.) Stapf.(lemongrass) against Aspergillus flavus Link. isolated from stored rice. Letters in Applied Microbiology, 37(1), 86-90.
  • [13] Ultee, A., & Smid, E. J. (2001). Influence of carvacrol on growth and toxin production by Bacillus cereus. International journal of food microbiology, 64(3), 373-378.
  • [14] Burt, S. (2004). Essential oils: their antibacterial properties and potential applications in foods—a review. International journal of food microbiology, 94(3), 223-253.
  • [15] Bakkali, F., Averbeck, S., Averbeck, D., & Idaomar, M. (2008). Biological effects of essential oils–a review. Food and chemical toxicology, 46(2), 446-475.
  • [16] Kordali, S., Kotan, R., Mavi, A., Cakir, A., Ala, A., & Yildirim, A. (2005). Determination of the chemical composition and antioxidant activity of the essential oil of Artemisia dracunculus and of the antifungal and antibacterial activities of Turkish Artemisia absinthium, A. dracunculus, Artemisia santonicum, and Artemisia spicigera essential oils. Journal of agricultural and food chemistry, 53(24), 9452-9458.
  • [17] Obolskiy, D., Pischel, I., Feistel, B., Glotov, N., & Heinrich, M. (2011). Artemisia dracunculus L.(tarragon): a critical review of its traditional use, chemical composition, pharmacology, and safety. Journal of Agricultural and Food Chemistry, 59(21), 11367-11384.
  • [18] Abad, M. J., Bedoya, L. M., Apaza, L., & Bermejo, P. (2012). The Artemisia L. genus: a review of bioactive essential oils. Molecules, 17(3), 2542-2566.
  • [19] İzgi, M. N. (2017). Farklı kişniş (Coriandrum sativum L.) popülasyon ve çeşitlerinde sıra arası mesafesinin tarımsal özellikleri ve sabit yağ oranına etkisi. KSÜ Doğa Bilimleri Dergisi, 20, 318-322.
  • [20] Diederichsen, A. (1996). Coriander: Coriandrum Sativum L (Vol. 3). Bioversity International.
  • [21] Eikani, M. H., Golmohammad, F., & Rowshanzamir, S. (2007). Subcritical water extraction of essential oils from coriander seeds (Coriandrum sativum L.). Journal of Food Engineering, 80(2), 735-740.
  • [22] Chatzifragkou, A., Petrou, I., Gardeli, C., Komaitis, M., & Papanikolaou, S. (2011). Effect of Origanum vulgare L. essential oil on growth and lipid profile of Yarrowia lipolytica cultivated on glycerol‐based media. Journal of the American Oil Chemists' Society, 88(12), 1955-1964.
  • [23] Telci, İ., Hışıl, Y. 2008. “Biomass Yield and Herb Essential Oil Characters at different Harvest Stages of Spring and Autumn Sown Coriandrum sativum”, European Journal of Horticultural Science, 73, 267-272.
  • [24] Linck, M.V., da Silva, A. L., Figueiró, M., Piato, A. L., Herrmann, A. P., Birck, F. D., ... & Elisabetsky, E. (2009). Inhaled linalool-induced sedation in mice. Phytomedicine, 16(4), 303-307.
  • [25] Sugawara, Y., Hara, C., Tamura, K., Fujii, T., Nakamura, K. I., Masujima, T., & Aoki, T. (1998). Sedative effect on humans of inhalation of essential oil of linalool:: Sensory evaluation and physiological measurements using optically active linalools. Analytica Chimica Acta, 365(1-3), 293-299.
  • [26] Peana, A. T., D'Aquila, P. S., Panin, F., Serra, G., Pippia, P., & Moretti, M. D. L. (2002). Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils. Phytomedicine, 9(8), 721-726.
  • [27] Suzuki, Y., Sakai, H., Shimada, T., Omura, M., Kumazawa, S., & Nakayama, T. (2004). Characterization of γ‐terpinene synthase from Citrus unshiu (Satsuma mandarin). BioFactors, 21(1‐4), 79-82.
  • [28] Yang, J., Nie, Q., Ren, M., Feng, H., Jiang, X., Zheng, Y., ... & Xian, M. (2013). Metabolic engineering of Escherichia coli for the biosynthesis of alpha-pinene. Biotechnology for biofuels, 6(1), 60.
  • [29] Gachkar, L., Yadegari, D., Rezaei, M. B., Taghizadeh, M., Astaneh, S. A., & Rasooli, I. (2007). Chemical and biological characteristics of Cuminum cyminum and Rosmarinus officinalis essential oils. Food chemistry, 102(3), 898-904.
  • [30] Ciriminna, R., Lomeli-Rodriguez, M., Cara, P. D., Lopez-Sanchez, J. A., & Pagliaro, M. (2014). Limonene: a versatile chemical of the bioeconomy. Chemical Communications, 50(97), 15288-15296.
  • [31] Chen, W., & Viljoen, A. M. (2010). Geraniol—a review of a commercially important fragrance material. South African Journal of Botany, 76(4), 643-651.
  • [32] Başer, K. H. C., Demirci, B., Dekebo, A., & Dagne, E. (2003). Essential oils of some Boswellia spp., myrrh and opopanax. Flavour and Fragrance Journal, 18(2), 153-156.
  • [33] Khani, A., & Rahdari, T. (2012). Chemical composition and insecticidal activity of essential oil from Coriandrum sativum seeds against Tribolium confusum and Callosobruchus maculatus. ISRN pharmaceutics, 2012.
  • [34] Pino, J. A., Rosado, A., & Fuentes, V. (1996a). Chemical composition of the seed oil of Coriandrum sativum L. from Cuba. Journal of essential oil research, 8(1), 97-98.
  • [35] Zoubiri, S., & Baaliouamer, A. (2010). Essential oil composition of Coriandrumsativum seed cultivated in Algeria as food grains protectant. Food chemistry, 122(4), 1226-1228.
  • [36] Bhuiyan, M. N. I., Begum, J., & Sultana, M. (2009). Chemical composition of leaf and seed essential oil of Coriandrum sativum L. from Bangladesh. Bangladesh Journal of Pharmacology, 4(2), 150-153.
  • [37] De Vincenzi, M., Silano, M., Maialetti, F., & Scazzocchio, B. (2000). Constituents of aromatic plants: II. Estragole. Fitoterapia, 71(6), 725-729.
  • [38] Johnson, J. D., Ryan, M. J., Toft, J. D., Graves, S. W., Hejtmancik, M. R., Cunningham, M. L., ... & Abdo, K. M. (2000). Two-year toxicity and carcinogenicity study of methyleugenol in F344/N rats and B6C3F1 mice. Journal of agricultural and food chemistry, 48(8), 3620-3632.
  • [39] Zeller, A., Horst, K., & Rychlik, M. (2009). Study of the metabolism of estragole in humans consuming fennel tea. Chemical research in toxicology, 22(12), 1929-1937.
  • [40] Gori, L., Gallo, E., Mascherini, V., Mugelli, A., Vannacci, A., & Firenzuoli, F. (2012). Can estragole in fennel seed decoctions really be considered a danger for human health? A fennel safety update. Evidence-Based Complementary and Alternative Medicine, 2012.
  • [41] Williams, G. M., Iatropoulos, M. J., Jeffrey, A. M., & Duan, J. D. (2013). Methyleugenol hepatocellular cancer initiating effects in rat liver. Food and chemical toxicology, 53, 187-196.
  • [42] Smith, R. L., Adams, T. B., Doull, J., Feron, V. J., Goodman, J. I., Marnett, L. J., ... & Caldwell, J. (2002). Safety assessment of allylalkoxybenzene derivatives used as flavouring substances—methyl eugenol and estragole. Food and chemical Toxicology, 40(7), 851-870.
  • [43] De Vincenzi, M., De Vincenzi, A., & Silano, M. (2004). Constituents of aromatic plants: elemicin. Fitoterapia, 75(6), 615-618.
  • [44] Yildizhan, S., & Schulz, S. (2011). Easy access to (E)-β-ocimene. Synlett, 2011(19), 2831-2833.
  • [45] Loughlin, R., Gilmore, B. F., McCarron, P. A., & Tunney, M. M. (2008). Comparison of the cidal activity of tea tree oil and terpinen‐4‐ol against clinical bacterial skin isolates and human fibroblast cells. Letters in applied microbiology, 46(4), 428-433.
  • [46] Mondello, F., De Bernardis, F., Girolamo, A., Cassone, A., & Salvatore, G. (2006). In vivo activity of terpinen-4-ol, the main bioactive component of Melaleuca alternifolia Cheel (tea tree) oil against azole-susceptible and-resistant human pathogenic Candida species. BMC infectious diseases, 6(1), 158.
  • [47] Pazyar, N., Yaghoobi, R., Bagherani, N., & Kazerouni, A. (2013). A review of applications of tea tree oil in dermatology. International Journal of Dermatology, 52(7), 784-790.
  • [48] De Sousa, D. P., Nóbrega, F. F., de Morais, L. C., & de Almeida, R. N. (2009). Evaluation of the anticonvulsant activity of terpinen-4-ol. Zeitschrift für Naturforschung C, 64(1-2), 1-5.
  • [49] Shapira, S., Pleban, S., Kazanov, D., Tirosh, P., & Arber, N. (2016). Terpinen-4-ol: A novel and promising therapeutic agent for human gastrointestinal cancers. PLoS One, 11(6), e0156540.
  • [50] Kim, Y. W., Kim, M. J., Chung, B. Y., Bang, D. Y., Lim, S. K., Choi, S. M., ... & Kim, K. B. (2013). Safety evaluation and risk assessment of d-limonene. Journal of Toxicology and Environmental Health, Part B, 16(1), 17-38.
  • [51] Crowell, P. L., Ayoubi, A. S., & Burke, Y. D. (1996). Antitumorigenic effects of limonene and perillyl alcohol against pancreatic and breast cancer. In Dietary Phytochemicals in Cancer Prevention and Treatment (pp. 131-136). Springer, Boston, MA.
  • [52] Pino, J. A., Rosado, A., Correa, M. T., & Fuentes, V. (1996b). Chemical composition of the essential oil of Artemisia dracunculus L. from Cuba. Journal of Essential Oil Research, 8(5), 563-564.
  • [53] Eisenman, S. W., Juliani, H. R., Struwe, L., & Simon, J. E. (2013). Essential oil diversity in North American wild tarragon (Artemisia dracunculus L.) with comparisons to French and Kyrgyz tarragon. Industrial crops and products, 49, 220-232.
  • [54] Lopes-Lutz, D., Alviano, D. S., Alviano, C. S., & Kolodziejczyk, P. P. (2008). Screening of chemical composition, antimicrobial and antioxidant activities of Artemisia essential oils. Phytochemistry, 69(8), 1732-1738.
  • [55] Sayyah, M., Nadjafnia, L., & Kamalinejad, M. (2004). Anticonvulsant activity and chemical composition of Artemisia dracunculus L. essential oil. Journal of Ethnopharmacology, 94(2-3), 283-287.
Yıl 2019, Cilt: 2 Sayı: 1, 26 - 33, 01.07.2019

Öz

Kaynakça

  • [1] Bayrak, A . (1985). Turunçgil uçucu yağları ve aromalarına etkili bazı bileşenler. Gıda, 10 (1) . Retrieved from http://dergipark.gov.tr/gida/issue/6924/92497.
  • [2] Ríos, J. L. (2016). Essential oils: What they are and how the terms are used and defined. In Essential Oils in Food Preservation, Flavor and Safety (pp. 3-10). Academic Press.
  • [3] Dima, C., & Dima, S. (2015). Essential oils in foods: extraction, stabilization, and toxicity. Current Opinion in Food Science, 5, 29-35.
  • [4] Deans, S. G., & Ritchie, G. (1987). Antibacterial properties of plant essential oils. International journal of food microbiology, 5(2), 165-180.
  • [5] Kalemba, D. A. A. K., & Kunicka, A. (2003). Antibacterial and antifungal properties of essential oils. Current medicinal chemistry, 10(10), 813-829.
  • [6] Soković, M., Glamočlija, J., Marin, P. D., Brkić, D., & van Griensven, L. J. (2010). Antibacterial effects of the essential oils of commonly consumed medicinal herbs using an in vitro model. Molecules, 15(11), 7532-7546.
  • [7] Koch, C., Reichling, J., Schneele, J., & Schnitzler, P. (2008). Inhibitory effect of essential oils against herpes simplex virus type 2. Phytomedicine, 15(1-2), 71-78.
  • [8] Orhan, İ. E., Özçelik, B., Kartal, M., & Kan, Y. (2012). Antimicrobial and antiviral effects of essential oils from selected Umbelliferae and Labiatae plants and individual essential oil components. Turkish Journal of Biology, 36(3), 239-246.
  • [9] Soylu, E. M., Kurt, Ş., & Soylu, S. (2010). In vitro and in vivo antifungal activities of the essential oils of various plants against tomato grey mould disease agent Botrytis cinerea. International Journal of Food Microbiology, 143(3), 183-189.
  • [10] Akgül, A., & Kivanc, M. (1988). Inhibitory effects of selected Turkish spices and oregano components on some foodborne fungi. International Journal of Food Microbiology, 6(3), 263-268.
  • [11] Graßmanna, J., Hippelia, S., Dornischa, K., Rohnerta, U., Beuscherb, N., & Elstnera, E. F. (2000). Antioxidant properties of essential oils. Arzneimittelforschung, 50(02), 135-139.
  • [12] Paranagama, P. A., Abeysekera, K. H. T., Abeywickrama, K., & Nugaliyadde, L. (2003). Fungicidal and anti‐aflatoxigenic effects of the essential oil of Cymbopogon citratus (DC.) Stapf.(lemongrass) against Aspergillus flavus Link. isolated from stored rice. Letters in Applied Microbiology, 37(1), 86-90.
  • [13] Ultee, A., & Smid, E. J. (2001). Influence of carvacrol on growth and toxin production by Bacillus cereus. International journal of food microbiology, 64(3), 373-378.
  • [14] Burt, S. (2004). Essential oils: their antibacterial properties and potential applications in foods—a review. International journal of food microbiology, 94(3), 223-253.
  • [15] Bakkali, F., Averbeck, S., Averbeck, D., & Idaomar, M. (2008). Biological effects of essential oils–a review. Food and chemical toxicology, 46(2), 446-475.
  • [16] Kordali, S., Kotan, R., Mavi, A., Cakir, A., Ala, A., & Yildirim, A. (2005). Determination of the chemical composition and antioxidant activity of the essential oil of Artemisia dracunculus and of the antifungal and antibacterial activities of Turkish Artemisia absinthium, A. dracunculus, Artemisia santonicum, and Artemisia spicigera essential oils. Journal of agricultural and food chemistry, 53(24), 9452-9458.
  • [17] Obolskiy, D., Pischel, I., Feistel, B., Glotov, N., & Heinrich, M. (2011). Artemisia dracunculus L.(tarragon): a critical review of its traditional use, chemical composition, pharmacology, and safety. Journal of Agricultural and Food Chemistry, 59(21), 11367-11384.
  • [18] Abad, M. J., Bedoya, L. M., Apaza, L., & Bermejo, P. (2012). The Artemisia L. genus: a review of bioactive essential oils. Molecules, 17(3), 2542-2566.
  • [19] İzgi, M. N. (2017). Farklı kişniş (Coriandrum sativum L.) popülasyon ve çeşitlerinde sıra arası mesafesinin tarımsal özellikleri ve sabit yağ oranına etkisi. KSÜ Doğa Bilimleri Dergisi, 20, 318-322.
  • [20] Diederichsen, A. (1996). Coriander: Coriandrum Sativum L (Vol. 3). Bioversity International.
  • [21] Eikani, M. H., Golmohammad, F., & Rowshanzamir, S. (2007). Subcritical water extraction of essential oils from coriander seeds (Coriandrum sativum L.). Journal of Food Engineering, 80(2), 735-740.
  • [22] Chatzifragkou, A., Petrou, I., Gardeli, C., Komaitis, M., & Papanikolaou, S. (2011). Effect of Origanum vulgare L. essential oil on growth and lipid profile of Yarrowia lipolytica cultivated on glycerol‐based media. Journal of the American Oil Chemists' Society, 88(12), 1955-1964.
  • [23] Telci, İ., Hışıl, Y. 2008. “Biomass Yield and Herb Essential Oil Characters at different Harvest Stages of Spring and Autumn Sown Coriandrum sativum”, European Journal of Horticultural Science, 73, 267-272.
  • [24] Linck, M.V., da Silva, A. L., Figueiró, M., Piato, A. L., Herrmann, A. P., Birck, F. D., ... & Elisabetsky, E. (2009). Inhaled linalool-induced sedation in mice. Phytomedicine, 16(4), 303-307.
  • [25] Sugawara, Y., Hara, C., Tamura, K., Fujii, T., Nakamura, K. I., Masujima, T., & Aoki, T. (1998). Sedative effect on humans of inhalation of essential oil of linalool:: Sensory evaluation and physiological measurements using optically active linalools. Analytica Chimica Acta, 365(1-3), 293-299.
  • [26] Peana, A. T., D'Aquila, P. S., Panin, F., Serra, G., Pippia, P., & Moretti, M. D. L. (2002). Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils. Phytomedicine, 9(8), 721-726.
  • [27] Suzuki, Y., Sakai, H., Shimada, T., Omura, M., Kumazawa, S., & Nakayama, T. (2004). Characterization of γ‐terpinene synthase from Citrus unshiu (Satsuma mandarin). BioFactors, 21(1‐4), 79-82.
  • [28] Yang, J., Nie, Q., Ren, M., Feng, H., Jiang, X., Zheng, Y., ... & Xian, M. (2013). Metabolic engineering of Escherichia coli for the biosynthesis of alpha-pinene. Biotechnology for biofuels, 6(1), 60.
  • [29] Gachkar, L., Yadegari, D., Rezaei, M. B., Taghizadeh, M., Astaneh, S. A., & Rasooli, I. (2007). Chemical and biological characteristics of Cuminum cyminum and Rosmarinus officinalis essential oils. Food chemistry, 102(3), 898-904.
  • [30] Ciriminna, R., Lomeli-Rodriguez, M., Cara, P. D., Lopez-Sanchez, J. A., & Pagliaro, M. (2014). Limonene: a versatile chemical of the bioeconomy. Chemical Communications, 50(97), 15288-15296.
  • [31] Chen, W., & Viljoen, A. M. (2010). Geraniol—a review of a commercially important fragrance material. South African Journal of Botany, 76(4), 643-651.
  • [32] Başer, K. H. C., Demirci, B., Dekebo, A., & Dagne, E. (2003). Essential oils of some Boswellia spp., myrrh and opopanax. Flavour and Fragrance Journal, 18(2), 153-156.
  • [33] Khani, A., & Rahdari, T. (2012). Chemical composition and insecticidal activity of essential oil from Coriandrum sativum seeds against Tribolium confusum and Callosobruchus maculatus. ISRN pharmaceutics, 2012.
  • [34] Pino, J. A., Rosado, A., & Fuentes, V. (1996a). Chemical composition of the seed oil of Coriandrum sativum L. from Cuba. Journal of essential oil research, 8(1), 97-98.
  • [35] Zoubiri, S., & Baaliouamer, A. (2010). Essential oil composition of Coriandrumsativum seed cultivated in Algeria as food grains protectant. Food chemistry, 122(4), 1226-1228.
  • [36] Bhuiyan, M. N. I., Begum, J., & Sultana, M. (2009). Chemical composition of leaf and seed essential oil of Coriandrum sativum L. from Bangladesh. Bangladesh Journal of Pharmacology, 4(2), 150-153.
  • [37] De Vincenzi, M., Silano, M., Maialetti, F., & Scazzocchio, B. (2000). Constituents of aromatic plants: II. Estragole. Fitoterapia, 71(6), 725-729.
  • [38] Johnson, J. D., Ryan, M. J., Toft, J. D., Graves, S. W., Hejtmancik, M. R., Cunningham, M. L., ... & Abdo, K. M. (2000). Two-year toxicity and carcinogenicity study of methyleugenol in F344/N rats and B6C3F1 mice. Journal of agricultural and food chemistry, 48(8), 3620-3632.
  • [39] Zeller, A., Horst, K., & Rychlik, M. (2009). Study of the metabolism of estragole in humans consuming fennel tea. Chemical research in toxicology, 22(12), 1929-1937.
  • [40] Gori, L., Gallo, E., Mascherini, V., Mugelli, A., Vannacci, A., & Firenzuoli, F. (2012). Can estragole in fennel seed decoctions really be considered a danger for human health? A fennel safety update. Evidence-Based Complementary and Alternative Medicine, 2012.
  • [41] Williams, G. M., Iatropoulos, M. J., Jeffrey, A. M., & Duan, J. D. (2013). Methyleugenol hepatocellular cancer initiating effects in rat liver. Food and chemical toxicology, 53, 187-196.
  • [42] Smith, R. L., Adams, T. B., Doull, J., Feron, V. J., Goodman, J. I., Marnett, L. J., ... & Caldwell, J. (2002). Safety assessment of allylalkoxybenzene derivatives used as flavouring substances—methyl eugenol and estragole. Food and chemical Toxicology, 40(7), 851-870.
  • [43] De Vincenzi, M., De Vincenzi, A., & Silano, M. (2004). Constituents of aromatic plants: elemicin. Fitoterapia, 75(6), 615-618.
  • [44] Yildizhan, S., & Schulz, S. (2011). Easy access to (E)-β-ocimene. Synlett, 2011(19), 2831-2833.
  • [45] Loughlin, R., Gilmore, B. F., McCarron, P. A., & Tunney, M. M. (2008). Comparison of the cidal activity of tea tree oil and terpinen‐4‐ol against clinical bacterial skin isolates and human fibroblast cells. Letters in applied microbiology, 46(4), 428-433.
  • [46] Mondello, F., De Bernardis, F., Girolamo, A., Cassone, A., & Salvatore, G. (2006). In vivo activity of terpinen-4-ol, the main bioactive component of Melaleuca alternifolia Cheel (tea tree) oil against azole-susceptible and-resistant human pathogenic Candida species. BMC infectious diseases, 6(1), 158.
  • [47] Pazyar, N., Yaghoobi, R., Bagherani, N., & Kazerouni, A. (2013). A review of applications of tea tree oil in dermatology. International Journal of Dermatology, 52(7), 784-790.
  • [48] De Sousa, D. P., Nóbrega, F. F., de Morais, L. C., & de Almeida, R. N. (2009). Evaluation of the anticonvulsant activity of terpinen-4-ol. Zeitschrift für Naturforschung C, 64(1-2), 1-5.
  • [49] Shapira, S., Pleban, S., Kazanov, D., Tirosh, P., & Arber, N. (2016). Terpinen-4-ol: A novel and promising therapeutic agent for human gastrointestinal cancers. PLoS One, 11(6), e0156540.
  • [50] Kim, Y. W., Kim, M. J., Chung, B. Y., Bang, D. Y., Lim, S. K., Choi, S. M., ... & Kim, K. B. (2013). Safety evaluation and risk assessment of d-limonene. Journal of Toxicology and Environmental Health, Part B, 16(1), 17-38.
  • [51] Crowell, P. L., Ayoubi, A. S., & Burke, Y. D. (1996). Antitumorigenic effects of limonene and perillyl alcohol against pancreatic and breast cancer. In Dietary Phytochemicals in Cancer Prevention and Treatment (pp. 131-136). Springer, Boston, MA.
  • [52] Pino, J. A., Rosado, A., Correa, M. T., & Fuentes, V. (1996b). Chemical composition of the essential oil of Artemisia dracunculus L. from Cuba. Journal of Essential Oil Research, 8(5), 563-564.
  • [53] Eisenman, S. W., Juliani, H. R., Struwe, L., & Simon, J. E. (2013). Essential oil diversity in North American wild tarragon (Artemisia dracunculus L.) with comparisons to French and Kyrgyz tarragon. Industrial crops and products, 49, 220-232.
  • [54] Lopes-Lutz, D., Alviano, D. S., Alviano, C. S., & Kolodziejczyk, P. P. (2008). Screening of chemical composition, antimicrobial and antioxidant activities of Artemisia essential oils. Phytochemistry, 69(8), 1732-1738.
  • [55] Sayyah, M., Nadjafnia, L., & Kamalinejad, M. (2004). Anticonvulsant activity and chemical composition of Artemisia dracunculus L. essential oil. Journal of Ethnopharmacology, 94(2-3), 283-287.
Toplam 55 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Mühendislik
Bölüm Araştırma Makaleleri
Yazarlar

Özlem Yılmaz 0000-0001-7113-8574

Güzin Kaban 0000-0001-6720-7231

Mükerrem Kaya 0000-0001-6340-828X

Yayımlanma Tarihi 1 Temmuz 2019
Yayımlandığı Sayı Yıl 2019 Cilt: 2 Sayı: 1

Kaynak Göster

APA Yılmaz, Ö., Kaban, G., & Kaya, M. (2019). Tarhun ve Kişniş Tohumunun Uçucu Yağ Bileşenleri. Bayburt Üniversitesi Fen Bilimleri Dergisi, 2(1), 26-33.
AMA Yılmaz Ö, Kaban G, Kaya M. Tarhun ve Kişniş Tohumunun Uçucu Yağ Bileşenleri. Bayburt Üniversitesi Fen Bilimleri Dergisi. Temmuz 2019;2(1):26-33.
Chicago Yılmaz, Özlem, Güzin Kaban, ve Mükerrem Kaya. “Tarhun Ve Kişniş Tohumunun Uçucu Yağ Bileşenleri”. Bayburt Üniversitesi Fen Bilimleri Dergisi 2, sy. 1 (Temmuz 2019): 26-33.
EndNote Yılmaz Ö, Kaban G, Kaya M (01 Temmuz 2019) Tarhun ve Kişniş Tohumunun Uçucu Yağ Bileşenleri. Bayburt Üniversitesi Fen Bilimleri Dergisi 2 1 26–33.
IEEE Ö. Yılmaz, G. Kaban, ve M. Kaya, “Tarhun ve Kişniş Tohumunun Uçucu Yağ Bileşenleri”, Bayburt Üniversitesi Fen Bilimleri Dergisi, c. 2, sy. 1, ss. 26–33, 2019.
ISNAD Yılmaz, Özlem vd. “Tarhun Ve Kişniş Tohumunun Uçucu Yağ Bileşenleri”. Bayburt Üniversitesi Fen Bilimleri Dergisi 2/1 (Temmuz 2019), 26-33.
JAMA Yılmaz Ö, Kaban G, Kaya M. Tarhun ve Kişniş Tohumunun Uçucu Yağ Bileşenleri. Bayburt Üniversitesi Fen Bilimleri Dergisi. 2019;2:26–33.
MLA Yılmaz, Özlem vd. “Tarhun Ve Kişniş Tohumunun Uçucu Yağ Bileşenleri”. Bayburt Üniversitesi Fen Bilimleri Dergisi, c. 2, sy. 1, 2019, ss. 26-33.
Vancouver Yılmaz Ö, Kaban G, Kaya M. Tarhun ve Kişniş Tohumunun Uçucu Yağ Bileşenleri. Bayburt Üniversitesi Fen Bilimleri Dergisi. 2019;2(1):26-33.

Taranılan Dizinler