Doğu Karadeniz’in Önemli Bir Tarım Zararlısı Orosanga japonica (Melichar, 1898) (Homoptera: Ricaniidae)’ya Karşı Bitkisel Asetilkolinesteraz İnhibitörlerinin Değerlendirilmesi Değerlendirilmesi

Demet Kızıl

doi:10.35229/jaes.1862726

EN TR

Evaluation of Plant-Based Acetylcholinesterase Inhibitors Against Orosanga japonica (Melichar, 1898) (Homoptera: Ricaniidae), an Important Agricultural Pest in the Eastern Black Sea Regionl Pest in the Eastern Black Sea Region

Öz

Acetylcholinesterase (AChE) is an important enzyme that plays a critical role in nerve transmission and is the primary target of many insecticides. Orosanga japonica is an invasive pest species that causes serious economic losses in agricultural production. Due to the environmental effects of synthetic insecticides, the development of natural and environmentally friendly alternatives has become important. In this study, the inhibitory effects of aqueous extracts obtained from sumac (Rhus coriaria L.), laurel (Laurus nobilis L.), Goji berry (Lycium barbarum L.), cornelian cherry (Cornus mas L.), and aronia (Aronia melanocarpa (Michx.) Elliott) were investigated for their inhibitory effects on AChE enzymes isolated from the nymph and adult stages of O. japonica under in vitro conditions. Among the positive controls, edrophonium chloride exhibited the strongest inhibitory effect, with IC₅₀ values of 0.76 ± 0.1 and 2.6 ± 0.5 µM for nymph and adult AChE, respectively. Among plant extracts, sumac fruit stood out as the most effective natural extract, exhibiting the lowest IC₅₀ values for both nymph (48.3 ± 8.2 µg dry matter/mL) and adult (66.1 ± 11.5 µg dry matter/mL) stages. In general, it was determined that AChE obtained from adult individuals showed lower sensitivity to inhibitors compared to the nymph stage. The findings indicate that all plant aqueous extracts studied exhibited inhibitory effects on O. japonica AChE at different levels and that sumac fruit extract, in particular, stands out as a promising candidate for the development of natural and environmentally friendly bioinsecticides due to its lower IC₅₀ values compared to other extracts.

Anahtar Kelimeler

Acetylcholinesterase, Biopesticides, İnhibition, Orosanga japonica, Pest Management

Doğu Karadeniz’in Önemli Bir Tarım Zararlısı Orosanga japonica (Melichar, 1898) (Homoptera: Ricaniidae)’ya Karşı Bitkisel Asetilkolinesteraz İnhibitörlerinin Değerlendirilmesi Değerlendirilmesi

Öz

Asetilkolinesteraz (AChE), sinir iletiminde kritik rol oynayan ve birçok insektisitin temel hedefi olan önemli bir enzimdir. Orosanga japonica, tarımsal üretimde ciddi ekonomik kayıplara yol açan istilacı bir zararlı tür olup, sentetik insektisitlerin çevresel etkileri nedeniyle doğal ve çevre dostu alternatiflerin geliştirilmesi önem kazanmaktadır. Bu çalışmada, sumak (Rhus coriaria L.), defne (Laurus nobilis L.), kurt üzümü (Lycium barbarum L.), kızılcık (Cornus mas L.) ve aronya (Aronia melanocarpa (Michx.) Elliott) bitkilerinden elde edilen sulu ekstraktların, O. japonica’nın nimf ve ergin dönemlerinden izole edilen AChE enzimleri üzerindeki inhibitör etkileri in vitro koşullarda araştırılmıştır. Pozitif kontrollerden edrofonyum klorit, nimf ve ergin AChE için sırasıyla 0,76 ± 0,1 ve 2,6 ± 0,5 µM IC₅₀ değerleriyle en güçlü inhibitör etkiyi göstermiştir. Bitkisel ekstraktlar arasında ise sumak meyvesi, nimf (48,3 ± 8,2 µg kuru madde/mL) ve ergin (66,1 ± 11,5 µg kuru madde/mL) dönemlerde en düşük IC₅₀ değerlerini sergileyerek en etkili doğal ekstrakt olarak öne çıkmıştır. Genel olarak, ergin bireylerden elde edilen AChE’nin nimf dönemine kıyasla inhibitörlere karşı daha düşük duyarlılık gösterdiği belirlenmiştir. Bulgular, incelenen tüm bitkisel sulu ekstraktların O. japonica AChE’si üzerinde farklı düzeylerde inhibitör etki gösterdiğini ve özellikle sumak meyvesi ekstraktının diğer ekstraktlara kıyasla daha düşük IC₅₀ değerleri sergilemesi nedeniyle doğal kökenli ve çevre dostu biyoinsektisitlerin geliştirilmesine yönelik umut verici bir aday olarak öne çıktığını göstermektedir

Anahtar Kelimeler

Asetilkolinesteraz, Biyopestisitler, Haşere Kontrolü, İnhibisyon, Orosanga japonica

Kaynakça

Abu-Reidah, I.M., Ali-Shtayeh, M.S., Jamous, R.M., Arráez-Román, D., & Segura-Carretero, A. (2015). HPLC-DAD-ESI-MS/MS screening of bioactive components from Rhus coriaria L. (Sumac) fruits. Food Chemistry, 166, 179-191. https://doi.org/10.1016/j.foodchem.2014.06.011
Al-Mijalli, S.H., Mrabti, H.N., Ouassou, H., Flouchi, R., Abdallah, E.M., Sheikh, R.A., Alshahrani, M.M., Awadh, A.A. Al, Harhar, H., Omari, N. El, Qasem, A., Assaggaf, H., Moursi, N.H., Bouyahya, A., Gallo, M., & Faouzi, M. E. A. (2022). Chemical Composition, Antioxidant, Anti-Diabetic, Anti-Acetylcholinesterase, Anti- Inflammatory, and Antimicrobial Properties of Arbutus unedo L. and Laurus nobilis L. Essential Oils. Life, 12(11), 1-21. https://doi.org/10.3390/life12111876
Alsamri, H., Athamneh, K., Pintus, G., Eid, A.H., & Iratni, R. (2021). Pharmacological and Antioxidant Activities of. antioxidants Review, 10(73), 1-27.
Altın, S., Işık, M., Alp, C., Dikici, E., Köksal, E., Kırboğa, K. K., Rudrapal, M., Rakshit, G., Beydemir, Ş., & Khan, J. (2025). Therapeutic potential of Laurus nobilis extract by experimental and computational approaches: phenolic content and bioactivities for antioxidant, antidiabetic, and anticholinergic properties. Frontiers in Chemistry, 13(February), 1-23. https://doi.org/10.3389/fchem.2025.1541250
Andrisano, V., Bartolini, M., Gotti, R., Cavrini, V., & Felix, G. (2001). Determination of inhibitors’ potency (IC50) by a direct high-performance liquid chromatographic method on an immobilised acetylcholinesterase column. Journal of Chromatography B: Biomedical Sciences and Applications, 753(2), 375-383. https://doi.org/10.1016/S0378-4347(00)00571-5
Bal, S., Kaya, R., Gök, Y., Taslimi, P., Aktaş, A., Karaman, M., & Gülçin, İ. (2020). Novel 2- methylimidazolium salts: Synthesis, characterization, molecular docking, and carbonic anhydrase and acetylcholinesterase inhibitory properties. Bioorganic Chemistry, 94. https://doi.org/10.1016/j.bioorg.2019.103468
Brinza, I., Boiangiu, R. S., Hancianu, M., Cioanca, O., Orhan, I.E., & Hritcu, L. (2021). Bay leaf (Laurus nobilis l.) incense improved scopolamine-induced amnesic rats by restoring cholinergic dysfunction and brain antioxidant status. Antioxidants, 10(2), 1-15. https://doi.org/10.3390/antiox10020259
Bughio, F.M., & Wilkins, R.M. (2004). Influence of malathion resistance status on survival and growth of Tribolium castaneum (Coleoptera: Tenebrionidae), when fed on flour from insect- resistant and susceptible grain rice cultivars. Journal of Stored Products Research, 40(1), 65- 75. https://doi.org/10.1016/S0022-474X(02)00077-2
Colovic, M.B., Krstic, D.Z., Lazarevic-Pasti, T.D., Bondzic, A.M., & Vasic, V.M. (2013). Acetylcholinesterase inhibitors: Pharmacology and toxicology. Current Neuropharmacology, 11(3), 315-335. https://doi.org/10.2174/1570159x11311030006
Czerwinska, M.E., & Melzig, M.F. (2018). Cornus mas and cornus officinalis-analogies and differences of two medicinal plants traditionally used. Frontiers in Pharmacology, 9(AUG), 1-28. https://doi.org/10.3389/fphar.2018.00894

Dawood, D.H., & Anwar, M.M. (2025). Recent advances in the therapeutic insights of thiazole scaffolds as acetylcholinesterase inhibitors. European Journal of Medicinal Chemistry, 287(January), 117331. https://doi.org/10.1016/j.ejmech.2025.117331
Demir, E. (2009). Ricania Germar, 1818 species of Western Palaearctic Region (Hemiptera: Fulgoromorpha: Ricaniidae). Munis Entomology Zoology, 4(1), 271-275.
Dinçer, B., & Akpınar, H. (2023). Purification of acetylcholinesterase from Halyomorpha halys (Stål) (Heteroptera: Pentatomidae) and management of control of the Pest through inhibition of the enzyme. International Journal of Tropical Insect Science, 43(5), 1421-1429. https://doi.org/10.1007/s42690-023-01047-x
Dinçer, B., & Kizil, D. (2022). Inhibition and purification of acetylcholinesterases from adults and nymphs of Ricania simulans (Walker, 1851) (Hemiptera: Ricaniidae). International Journal of Tropical Insect Science, 42(5), 3363-3372. https://doi.org/10.1007/s42690-022-00835-1
Dos Reis, V.E.N., Dinamarco, T.M., & Cardoso, C.L. (2025). Purification, characterization, and inhibition studies of a new acetylcholinesterase obtained from the neotropical brown stink bug Euschistus heros. International Journal of Biological Macromolecules, 287(October 2024), 138578. https://doi.org/10.1016/j.ijbiomac.2024.138578
Duranay, S., Anil, S., Hasbal, G., & Özsoy, N. (2019). Purification of acethylcholinesterase from the mollusc Mytilus galloprovincialis Lam. and investigation of its kinetic properties. Journal of Research in Pharmacy, 23(4), 759-769. https://doi.org/10.12991/jrp.2019.185
Dzydzan, O., Brodyak, I., Strugała-Danak, P., Strach, A., Kucharska Z., A., Gabrielska, J., & Sybirna, N. (2022). Biological Activity of Extracts of Red and Yellow Fruits of Cornus mas L.-An In Vitro Evaluation of Antioxidant Activity, Inhibitory Activity against α. Molecules, 27. https://www.mdpi.com/1420-3049/27/7/2244
Ellman, G.L., Courtney, K.D., Andres, V., & Featherstone, R.M. (1961). A new and rapid colorimetric determination of acetylcholinesterase activity. Biochemical Pharmacology, 7(2), 2-3. https://doi.org/10.1016/0006-2952(61)90145-9
Falade, A.O., Omolaiye, G.I., Adewole, K.E., Agunloye, O.M., Ishola, A.A., Okaiyeto, K., Oboh, G., & Oguntibeju, O.O. (2022). Aqueous Extracts of Bay Leaf (Laurus nobilis) and Rosemary (Rosmarinus officinalis) Inhibit Iron-Induced Lipid Peroxidation and Key-Enzymes Implicated in Alzheimer’s Disease in Rat Brain-in Vitro. American Journal of Biochemistry and Biotechnology, 18(1), 9-22. https://doi.org/10.3844/ajbbsp.2022.9.22
Farag, M.R., Alagawany, M., Bilal, R.M., Gewida, A.G.A., Dhama, K., Abdel-Latif, H.M.R., Amer, M.S., Rivero-Perez, N., Zaragoza- Bastida, A., Binnaser, Y.S., Batiha, G.E.S., & Naiel, M.A.E. (2021). An overview on the potential hazards of pyrethroid insecticides in fish, with special emphasis on cypermethrin toxicity. Animals, 11(7). https://doi.org/10.3390/ani11071880
Ferreira, A., Proença, C., Serralheiro, M.L.M., & Araújo, M.E.M. (2006). The in vitro screening for acetylcholinesterase inhibition and antioxidant activity of medicinal plants from Portugal. Journal of Ethnopharmacology, 108(1), 31-37. https://doi.org/10.1016/j.jep.2006.04.010
Gazwi, H.S.S., Yassien, E.E., & Hassan, H.M. (2020). Mitigation of lead neurotoxicity by the ethanolic extract of Laurus leaf in rats. Ecotoxicology and Environmental Safety, 192(January), 110297. https://doi.org/10.1016/j.ecoenv.2020.110297
Gezici, S. (2019). Neuroprotective Effect, Antimicrobial and Antioxidant Potentials of Sumac (Rhus coriaria L.) Fruit Extracts. Hacettepe Journal of Biology and Chemistry, 47(2), 165-170. https://doi.org/10.15671/hjbc.621202
Göktürk, T. (2020). Bazı entomopatojenlerin Orosanga japonica (Hemiptera: Ricaniidae) üzerindeki öldürücü etkilerinin belirlenmesi. Türkiye Tarımsal Araştırmalar Dergisi, 7(3), 305-314. https://doi.org/10.19159/tutad.771088
Gokturk, T., Kordali, S., & Bozhuyuk Usanmaz, A. (2017). Insecticidal effects of essential oils against nymphal and adult stage of Ricania simulans (Hemiptera: Ricanidae). Natural Product Communications, 12(8.5.2017), 973-976.
Göktürk, T., & Mıhlı, A. (2015). Doğu Karadeniz sahil şeridinin önemli zararlısı Ricania simulans (Walker) 1851 (Hemiptera: Ricaniidae)’un mücadelesi üzerine araştırmalar. Artvin Çoruh Üniversitesi Orman Fakültesi Dergisi, 16(1). https://doi.org/10.17474/acuofd.44749
Ismaylova, G. (2021). New record of. Punjab University Journal of Zoology, 36(2), 141-145.
Guo, Y., Yang, H., Huang, Z., Tian, S., Li, Q., Du, C., Chen, T., Liu, Y., Sun, H., & Liu, Z. (2020). Design, synthesis, and evaluation of acetylcholinesterase and butyrylcholinesterase dual-target inhibitors against Alzheimer’s diseases. Molecules, 25, 1-21. https://doi.org/10.3390/molecules25030489
Jurikova, T., Tinakova, S.M., Ziarovska, J., Szekeres, L., Mlcek, J., Fatrcova-Sramkova, K., Knazicka, Z., & Skrovankova, S. (2025). Polyphenolic Spectrum of Goji Berries and Their Health-Promoting Activity. Foods, 14(8), 1-23. https://doi.org/10.3390/foods14081387
Kızıl, D. (2025a). Inhibition Effect of Some Plant Extracts on Calliteara pudibunda (Linneaus, 1758) Acetylcholinesterase. Journal of Anatolian Environmental and Animal Sciences, 10(2), 151- 158. https://doi.org/10.35229/jaes.1613209, https://izlik.org/JA99UR24FK
Kızıl, D. (2025b). Investigation of Biopesticides for the Pest Control Through Inhibition of the Acetylcholinesterase Purified from Loxostege sticticalis (L.) (Lepidoptera: Crambidae). Applied Biochemistry and Biotechnology, 0123456789. https://doi.org/10.1007/s12010-025-05363-5
Komloova, M., Musilek, K., Horova, A., Holas, O., Dohnal, V., Gunn-Moore, F., & Kuca, K. (2011). Preparation, in vitro screening and molecular modelling of symmetrical bis- quinolinium cholinesterase inhibitors - Implications for early Myasthenia gravis treatment. Bioorganic and Medicinal Chemistry Letters, 21(8), 2505-2509. https://doi.org/10.1016/j.bmcl.2011.02.047
Lingk, W. (1991). Health risk evaluation of pesticide contaminations in drinking water.
Martín-Blosca, Y., Asensi-Bernardi, L., Villanueva- Camañas, R.M., Sagrado, S., & Medina- Hernández, M.J. (2009). Screening of acetylcholinesterase inhibitors by CE after enzymatic reaction at capillary inlet. Journal of Separation Science, 32(10), 1748-1756. https://doi.org/10.1002/jssc.200800701
Mishra, A.K., & Dubey, N.K. (1990). Fungitoxicity of essential oil of Amomum subulatum Against Aspergillus flavus. Economic Botany, 44(4), 530- 533.
Mocan, A., Moldovan, C., Zengin, G., Bender, O., Locatelli, M., Simirgiotis, M., Atalay, A., Vodnar, D. C., Rohn, S., ve Crișan, G. (2018). UHPLC-QTOF-MS analysis of bioactive constituents from two Romanian Goji (Lycium barbarum L.) berries cultivars and their antioxidant, enzyme inhibitory, and real-time cytotoxicological evaluation. Food and Chemical Toxicology, 115(February), 414-424. https://doi.org/10.1016/j.fct.2018.01.054
Mutunga, J.M., Anderson, T.D., Wong, D.M., Carlier, P.R., & Bloomquist, J.R. (2009). Inhibition of Blattella germanica acetylcholinesterase by Bis(n)-tacrines: Prospects for the molecular design of a selective insecticide for a household pest. ACS Symposium Series, 1015, 41-51. https://doi.org/10.1021/bk-2009-1015.ch004
Nasar-Abbas, S.M., & Halkman, A.K. (2004). Antimicrobial effect of water extract of sumac (Rhus coriaria L.) on the growth of some food borne bacteria including pathogens. International Journal of Food Microbiology, 97(1), 63-69. https://doi.org/10.1016/j.ijfoodmicro.2004.04.009
Özbucak, T., & Gümüş, A.F. (2024). Aronya Meyvesinin Ekolojik ve Fitokimyasal Varyasyonlarının Belirlenmesi. Türk Tarım ve Doğa Bilimleri Dergisi, 11(4), 1035-1045. https://doi.org/10.30910/turkjans.1499475
Pomianek, T., Zagórska-Dziok, M., Skóra, B., Ziemlewska, A., Nizioł-Łukaszewska, Z., Wójciak, M., Sowa, I., & Szychowski, K. A. (2024). Comparison of the Antioxidant and Cytoprotective Properties of Extracts from Different Cultivars of Cornus mas L. International Journal of Molecular Sciences, 25(10). https://doi.org/10.3390/ijms25105495
Pope, C.N. (1999). Organophosphorus pesticides: Do they all have the same mechanism of toxicity. Journal of Toxicology and Environmental Health - Part B: Critical Reviews, 2(2), 161-181. https://doi.org/10.1080/109374099281205
Pundir, C.S., & Chauhan, N. (2012). Acetylcholinesterase inhibition-based biosensors for pesticide determination: A review. Analytical Biochemistry, 429(1), 19-31. https://doi.org/10.1016/j.ab.2012.06.025
Rampa, A., Bisi, A., Belluti, F., Gobbi, S., Valenti, P., Andrisano, V., Cavrini, V., Cavalli, A., & Recanatini, M. (2000). Acetylcholinesterase inhibitors for potential use in Alzheimer’s disease: Molecular modeling, synthesis and kinetic evaluation of 11H-indeno-[1,2-b]-quinolin-10- ylamine derivatives. Bioorganic and Medicinal Chemistry, 8(3), 497-506. https://doi.org/10.1016/S0968-0896(99)00306-5
Rayne, S., & Mazza, G. (2007). Biological activities of extracts from sumac (Rhus spp.): A review. Plant Foods for Human Nutrition, 62(4), 165175. https://doi.org/10.1007/s11130-007-0058-4
Scott, I.M., Jensen, H., Scott, J.G., Isman, M.B., Arnason, J.T., & Philogène, B.J.R. (2003). Botanical insecticides for controlling agricultural pests: Piperamides and the Colorado potato beetle Leptinotarsa decemlineata say (Coleoptera: Chrysomelidae). Archives of Insect Biochemistry and Physiology, 54(4), 212-225. https://doi.org/10.1002/arch.10118
Seto, Y., & Shinohara, T. (1988). Structure-activity relationship of reversible cholinesterase inhibitors including paraquat. Archives of Toxicology, 62(1), 37-40. https://doi.org/10.1007/BF00316254
Sultana, R. (2021). Aronia melanocarpa: A Review of Potential Antioxidants on Neuroprotection and Cognitive Performance. Journal of Drug Vigilance and Alternative Therapies, 1(3), 92- 100. https://doi.org/10.52816/jdvat.2021.1301
Wang, H., Yan, Z., Yang, W., Liu, R., Fan, G., Gu, Z., & Tang, Z. (2025). A strategy of monitoring acetylcholinesterase and screening of natural inhibitors from Uncaria for Alzheimer’s disease therapy based on near-infrared fluorescence probe. Sensors and Actuators B: Chemical, 424(October 2024), 136895. https://doi.org/10.1016/j.snb.2024.136895
Weinstock, M. (1999). Selectivity of cholinesterase inhibition: Clinical implications for the treatment of Alzheimer’s disease. CNS Drugs, 12(4), 307- 323. https://doi.org/10.2165/00023210- 199912040-00005
Wojdyło, A., Nowicka, P., & Bąbelewski, P. (2018). Phenolic and carotenoid profile of new goji cultivars and their anti-hyperglycemic, anti-aging and antioxidant properties. Journal of Functional Foods, 48(August), 632-642. https://doi.org/10.1016/j.jff.2018.07.061
Yamamoto, K., Sawada, Y., & Iga, T. (1996). Pharmacodynamic analysis of contractile potentiation by cholinesterase inhibitors in rats. Journal of Pharmacokinetics and Biopharmaceutics, 24(4), 327-348. https://doi.org/10.1007/BF02353516
Zdunić, G., Aradski, A.A., Gođevac, D., Živković, J., Laušević, S.D., Milošević, D.K., & Šavikin, K. (2020). In vitro hypoglycemic, antioxidant and antineurodegenerative activity of chokeberry (Aronia melanocarpa) leaves. Industrial Crops and Products, 148(August 2019). https://doi.org/10.1016/j.indcrop.2020.112328

Ayrıntılar

Birincil Dil

Türkçe

Konular

Entomoloji, Koruma ve Biyolojik Çeşitlilik

Bölüm

Araştırma Makalesi

Yazarlar

Demet Kızıl ^*
0000-0002-2346-7514
Türkiye

Yayımlanma Tarihi

17 Mart 2026

Gönderilme Tarihi

13 Ocak 2026

Kabul Tarihi

25 Şubat 2026

Yayımlandığı Sayı

Yıl 2026 Sayı: 2026

DOI

https://doi.org/10.35229/jaes.1862726

IZ

https://izlik.org/JA37MP68LW

APA

Kızıl, D. (2026). Doğu Karadeniz’in Önemli Bir Tarım Zararlısı Orosanga japonica (Melichar, 1898) (Homoptera: Ricaniidae)’ya Karşı Bitkisel Asetilkolinesteraz İnhibitörlerinin Değerlendirilmesi Değerlendirilmesi. Journal of Anatolian Environmental and Animal Sciences, 2026. https://doi.org/10.35229/jaes.1862726

AMA

1.Kızıl D. Doğu Karadeniz’in Önemli Bir Tarım Zararlısı Orosanga japonica (Melichar, 1898) (Homoptera: Ricaniidae)’ya Karşı Bitkisel Asetilkolinesteraz İnhibitörlerinin Değerlendirilmesi Değerlendirilmesi. Journal of Anatolian Environmental and Animal Sciences. 2026;(2026). doi:10.35229/jaes.1862726

Chicago

Kızıl, Demet. 2026. “Doğu Karadeniz’in Önemli Bir Tarım Zararlısı Orosanga japonica (Melichar, 1898) (Homoptera: Ricaniidae)’ya Karşı Bitkisel Asetilkolinesteraz İnhibitörlerinin Değerlendirilmesi Değerlendirilmesi”. Journal of Anatolian Environmental and Animal Sciences, sy 2026. https://doi.org/10.35229/jaes.1862726.

EndNote

Kızıl D (01 Mart 2026) Doğu Karadeniz’in Önemli Bir Tarım Zararlısı Orosanga japonica (Melichar, 1898) (Homoptera: Ricaniidae)’ya Karşı Bitkisel Asetilkolinesteraz İnhibitörlerinin Değerlendirilmesi Değerlendirilmesi. Journal of Anatolian Environmental and Animal Sciences 2026

IEEE

[1]D. Kızıl, “Doğu Karadeniz’in Önemli Bir Tarım Zararlısı Orosanga japonica (Melichar, 1898) (Homoptera: Ricaniidae)’ya Karşı Bitkisel Asetilkolinesteraz İnhibitörlerinin Değerlendirilmesi Değerlendirilmesi”, Journal of Anatolian Environmental and Animal Sciences, sy 2026, Mar. 2026, doi: 10.35229/jaes.1862726.

ISNAD

Kızıl, Demet. “Doğu Karadeniz’in Önemli Bir Tarım Zararlısı Orosanga japonica (Melichar, 1898) (Homoptera: Ricaniidae)’ya Karşı Bitkisel Asetilkolinesteraz İnhibitörlerinin Değerlendirilmesi Değerlendirilmesi”. Journal of Anatolian Environmental and Animal Sciences. 2026 (01 Mart 2026). https://doi.org/10.35229/jaes.1862726.

JAMA

1.Kızıl D. Doğu Karadeniz’in Önemli Bir Tarım Zararlısı Orosanga japonica (Melichar, 1898) (Homoptera: Ricaniidae)’ya Karşı Bitkisel Asetilkolinesteraz İnhibitörlerinin Değerlendirilmesi Değerlendirilmesi. Journal of Anatolian Environmental and Animal Sciences. 2026. doi:10.35229/jaes.1862726.

MLA

Kızıl, Demet. “Doğu Karadeniz’in Önemli Bir Tarım Zararlısı Orosanga japonica (Melichar, 1898) (Homoptera: Ricaniidae)’ya Karşı Bitkisel Asetilkolinesteraz İnhibitörlerinin Değerlendirilmesi Değerlendirilmesi”. Journal of Anatolian Environmental and Animal Sciences, sy 2026, Mart 2026, doi:10.35229/jaes.1862726.

Vancouver

1.Demet Kızıl. Doğu Karadeniz’in Önemli Bir Tarım Zararlısı Orosanga japonica (Melichar, 1898) (Homoptera: Ricaniidae)’ya Karşı Bitkisel Asetilkolinesteraz İnhibitörlerinin Değerlendirilmesi Değerlendirilmesi. Journal of Anatolian Environmental and Animal Sciences. 01 Mart 2026;(2026). doi:10.35229/jaes.1862726

JAES, 2016- 11.yıl

Evaluation of Plant-Based Acetylcholinesterase Inhibitors Against Orosanga japonica (Melichar, 1898) (Homoptera: Ricaniidae), an Important Agricultural Pest in the Eastern Black Sea Regionl Pest in the Eastern Black Sea Region

Öz

Anahtar Kelimeler

Doğu Karadeniz’in Önemli Bir Tarım Zararlısı Orosanga japonica (Melichar, 1898) (Homoptera: Ricaniidae)’ya Karşı Bitkisel Asetilkolinesteraz İnhibitörlerinin Değerlendirilmesi Değerlendirilmesi

Öz

Anahtar Kelimeler

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

Kaynak Göster